América vs Guadalajara Prediction, Betting Tips, Lineups & Odds | 13 Sep 2025

Liga MX Betting Preview: América vs Guadalajara

América host Guadalajara in this Liga MX clash at Estadio Azteca, with kick-off set for 23:15 on Saturday 13 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

Will the Favourites Cover the Line?

One way of backing América to get the better of Guadalajara is taking them at -0.75 on the Asian Handicap. You can bet at odds of -127, with your stake evenly split between -0.5 and -1.

Thinking of placing an Asian Handicap wager? Use the latest BetMGM promo code and check out our comprehensive expert site review before putting money down.

América 4-0 Winners in Most Recent H2H

Club América last Liga MX game was a 2-0 home victory. This win over Pachuca at Estadio Azteca was their fourth consecutive league victory. The Mexico City outfit recorded 47% possession and managed five shots on target, with Igor Lichnovsky and Allan Saint-Maximin each scoring one goal.

Guadalajara lost their previous game, being beaten at home to Cruz Azul by a 2-1 scoreline at Estadio Akron. Gabriel Milito's team enjoyed 61% possession and had six shots on goal, with Diego Campillo on the scoresheet.

Head-to-Head Statistics

América had the edge in the most recent encounter between these teams, recording a 4-0 CONCACAF Champions Cup home win over Guadalajara at Estadio de la Ciudad de los Deportes. In the past 10 H2H meetings, we have seen five América wins, two Guadalajara victories and three draws.

Liga MX		G	W	D	L	GF	GA	GD	GD	P
2	América	7	5	2	0	15	6	9	15:6	17
16	Guadalajara	6	1	1	4	9	12	-3	9:12	4

View Full Table

6 wins, 1 loss and 3 draws, averaging 1.7 goals from 4.2 shots on goal and 8.7 attempts. Club América have had 60.1% possession and 4.6 corners per game. On average, they have conceded 0.9 goals from 2.8 shots on goal and 6.9 attempts, while the opposition have been awarded 3.6 corners.

Top goalscorer Brian Rodriguez has found the net 3 times, with Allan Saint-Maximin and Erick Sanchez scoring 2 each. Isaias Violante, Cristian Borja and Brian Rodriguez have racked up the most assists with 2 each.

Chivas have won 2, lost 5 and drawn 3, averaging 11.7 attempts, 4.9 shots on goal and 1.3 goals. Gabriel Milito's men average 57.9% possession, 6.2 corners awarded and 4.3 corners against them, while 1.7 goals have been conceded from 4.8 shots on goal and 8.3 attempts.

Armando Gonzalez has landed 3 goals, Roberto Alvarado 2, with Diego Campillo and two others scoring 1. Look no further than Miguel Gomez for the top assist maker (2) in the last 10 games.

Predicted & Confirmed Lineups

América predicted lineup (4-4-2): Luis Malagón (GK), Dagoberto Espinoza, Sebastián Cáceres, Igor Lichnovsky, Cristian Borja, Israel Reyes Romero, Álvaro Fidalgo, Erick Sánchez, Allan Saint-Maximin, Alejandro Zendejas, José Zúñiga.

Guadalajara predicted lineup (3-4-1-2): José Raúl Rangel (GK), Diego Campillo, Gilberto Sepúlveda, Miguel Tapias, Roberto Alvarado, Luis Francisco Romo, Érick Gutiérrez, Bryan González, Santiago Sandoval, Armando González, Efrain Álvarez.

América vs Guadalajara Prediction & Betting Tips

Get set for América vs Guadalajara with our full betting breakdown, complete with an expert match prediction, a likely final score, top corners play, player prop picks and a value-driven bet builder.

Match Prediction

América look like excellent value at -127 on the Asian Handicap. You can take the favourites at -0.75 for this Liga MX match and there’s a strong case that they’ll have the upper hand here.

When it comes to making our expert football predictions, it’s important to study team news and observe the latest form. There are lots of Liga MX stats that can also help to shape our picks.

Key América vs Guadalajara league stats:

• The -0.75 line has been covered by América in 4 consecutive games.
• The -0.75 line has been covered by América in 8 of their last 10 games at home.
• The -0.75 line has been covered by América in 14 of their last 20 games at home.
• The +0.75 line hasn’t been covered by Guadalajara in 3 of their last 5 games.
• The +0.75 line hasn’t been covered by Guadalajara in 10 of their last 18 games on the road.

América -0.75 Probability

According to the top betting sites, our pick has a 55.9% chance of landing a return. After careful examination, our experts calculate this probability to be somewhere between 60-65%. It’s the reason why we are recommending this bet.

It’s great to place a Winning Margin wager if you want an alternative to Asian Handicap. Choose whether a team will achieve a close victory or something bigger.

Before placing your bets, explore the latest betting offers. Our comprehensive guide features a wide range of welcome bonuses to choose from.

Our Match Prediction

América Asian Hcp -0.75 @ -127 Watch Live Bet Now

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Correct Score Prediction

América 2 - 0 Guadalajara

We’ve got a correct score prediction which involves América winning 2-0. Odds of +600 look appealing and we should get a run for our money here.

Player Prop Picks

Top Pick: Álex Zendejas To Score +290

Álex Zendejas (América) can be backed to score at +290. It’s worth a gamble on him to be Anytime Goalscorer as there’s plenty of juice in these betting odds.

Latest Álex Zendejas Player Prop Odds

Goalscorer

Anytime

+290

First

+800

Shots On Target

Over 0.5

+105

Under 0.5

-167

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Corners Prediction

Guadalajara Over 3.5 Corners -156

The 3.5 corners line has been covered by Guadalajara in their past eight games, while the previous 5 América matches have seen them concede an average of 4.60 corners. Guadalajara should be capable of covering the line when it comes to Team Corners and odds of -156 are on offer.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

América

Total

8.20 4.60 3.60

Home

10.00 5.90 4.10

Away

8.30 3.50 4.80

Guadalajara

Total

10.50 6.20 4.30

Home

11.10 6.20 4.90

Away

10.90 6.30 4.60

Latest Corner Odds

Total Corners

Over 10.5

-110

Under 10.5

-135

América Corners

Over 5.5

-120

Under 5.5

-120

Guadalajara Corners

Over 4.5

+110

Under 4.5

-150

Most Corners

1

-263

X

+750

2

+260

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América vs Guadalajara Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

América Made Favourites by the Bookies

For this Liga MX encounter, the bookmakers have Club América as the -172 favourites to win. This therefore implies that they have a 63% chance of triumphing. Guadalajara are the underdogs at +400 which implies a lesser percentage prospect of winning.

It sometimes pays to go down the Half-Time Result route and the draw is available at +130. Alternatively, América can be backed at +114 and Guadalajara are on offer at +375.

The Total Goals market reveals that Over 2.5 Goals is the current betting favourite. When it comes to BTTS betting, the market suggests that Both Teams to Score Yes and No are both equally as likely to happen.

The top football betting sites are on hand to provide lots of choice to bettors. It’s now the case that you can select from hundreds of markets for all of the Liga MX games.

Full-Time Result

1

-172

X

+310

2

+400

Half-Time Result

1

+114

X

+130

2

+375

Double Chance

1X

-769

12

-556

X2

+112

Draw No Bet

1

-400

2

+260

Asian Handicap

1 Hcp -0.75

-127

2 Hcp +0.75

+102

Total Goals

Under 2.5

-103

Over 2.5

-132

Both Teams to Score

Yes

-125

No

-114

Henry Martín Favourite to Be First Goalscorer

Those interested in Henry Martín to find the net anytime are able to get +170. There is the chance to back the favourite to score the first goal at odds of +450.

Henry Martín (América)

First

+170

Anytime

+450

Rodrigo Aguirre (América)

First

+180

Anytime

+480

Patricio Salas (América)

First

+220

Anytime

+575

Paul Brian Rodríguez (América)

First

+240

Anytime

+600

Álex Zendejas (América)

First

+290

Anytime

+800

Javairô Dilrosun (América)

First

+320

Anytime

+850

Alan Pulido (Guadalajara)

First

+330

Anytime

+850

Javier Hernández (Guadalajara)

First

+350

Anytime

+850

Allan Saint-Maximin (América)

First

+370

Anytime

+1000

Roberto Alvarado (Guadalajara)

First

+400

Anytime

+1000

Erick Sanchez (América)

First

+420

Anytime

+1200

Aarón Arredondo (América)

First

+450

Anytime

+1200

Álvaro Fidalgo (América)

First

+450

Anytime

+1100

Cade Cowell (Guadalajara)

First

+475

Anytime

+1150

Armando González (Guadalajara)

First

+500

Anytime

+1200

Dagoberto Espinoza (América)

First

+525

Anytime

+1400

Isaác Brizuela (Guadalajara)

First

+550

Anytime

+1400

Jonathan dos Santos (América)

First

+650

Anytime

+1700

Israel Reyes (América)

First

+700

Anytime

+2000

Kevin Alvarez (América)

First

+750

Anytime

+2000

Miguel Vazquez (América)

First

+850

Anytime

+2200

Henry Martín (América)

Over 0.5

-213

Under 0.5

+132

Rodrigo Aguirre (América)

Over 0.5

-179

Under 0.5

+112

Patricio Salas (América)

Over 0.5

-143

Under 0.5

-110

Paul Brian Rodríguez (América)

Over 0.5

-118

Under 0.5

-133

Álex Zendejas (América)

Over 0.5

+105

Under 0.5

-167

Alan Pulido (Guadalajara)

Over 0.5

+110

Under 0.5

-175

Allan Saint-Maximin (América)

Over 0.5

+112

Under 0.5

-179

Javier Hernández (Guadalajara)

Over 0.5

+115

Under 0.5

-185

Javairô Dilrosun (América)

Over 0.5

+125

Under 0.5

-200

Roberto Alvarado (Guadalajara)

Over 0.5

+135

Under 0.5

-217

Erick Sanchez (América)

Over 0.5

+160

Under 0.5

-263

Cade Cowell (Guadalajara)

Over 0.5

+170

Under 0.5

-294

Armando González (Guadalajara)

Over 0.5

+170

Under 0.5

-294

Álvaro Fidalgo (América)

Over 0.5

+175

Under 0.5

-294

Aarón Arredondo (América)

Over 0.5

+180

Under 0.5

-313

Isaác Brizuela (Guadalajara)

Over 0.5

+195

Under 0.5

-333

Dagoberto Espinoza (América)

Over 0.5

+240

Under 0.5

-435

Israel Reyes (América)

Over 0.5

+285

Under 0.5

-588

Kevin Alvarez (América)

Over 0.5

+300

Under 0.5

-625

América Unbeaten at Home in Past Ten Games

América haven’t been beaten in ten straight games at Estadio Azteca. Andre Jardine's team have eight victories and two draws in the last 10 home matches, recording an average of 2.10 goals per game and conceding 0.20.

Guadalajara haven’t triumphed in seven straight games on the road. Guadalajara have managed five losses, four draws and one victory in the last 10 away matches, recording an average of 1.00 goals per game and conceding 1.60.

América beat Guadalajara 4-0 when they last met at Estadio Azteca. The previous 10 H2H matches at Estadio Azteca have seen América win six times, one draw and three Guadalajara triumphs.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
América Home Stats		8-2-0	2.30	2.10	0.20	5	5	2	8
Guadalajara Away Stats		1-4-5	2.60	1.00	1.60	4	6	7	3

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

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América vs Guadalajara Lineups & Team News

The latest América vs Chivas team news could impact your bets — review it first. We’ll have the predicted and confirmed Liga MX lineups for you plus all the latest on player injuries.

América Team Page Guadalajara Team Page