Cruz Azul vs Santos Laguna Prediction, Betting Tips, Lineups & Odds | 16 Aug 2025

Liga MX Betting Preview: Cruz Azul vs Santos Laguna

Cruz Azul host Santos Laguna in this Liga MX match at Estadio Azteca, with kick-off set for 21:00 on Saturday 16 August 2025. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

Straightforward Win on the Cards for Cruz Azul

We’re expecting Cruz Azul to enjoy a big win against Santos Laguna. Backing the favourites at -1.75 at odds of -114 means that we split our Asian Handicap stake equally between -1.5 and -2.0. A three-goal margin of victory lands a full payout.

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1-0 Win for Cruz Azul in Last H2H Battle

Cruz Azul have triumphed in back-to-back Liga MX games. The latest of these was on the road where Atlético San Luis were beaten 2-1 at Estadio Alfonso Lastras. The Mexico City side had six shots on target and enjoyed 62% possession, while Carlos Rodolfo Rotondi and Angel Sepulveda each scored one goal.

Santos Laguna won their previous game which was at home. It was a 1-0 triumph at Estadio Nuevo Corona against Guadalajara. Los Guerreros had just 34% possession and totalled two shots on goal, with Bruno Barticciotto scoring the winner in the 29th minute.

Head-to-Head Statistics

Cruz Azul have beaten Santos in the last two clashes. When travelling to Estadio Nuevo Corona, the scoreline was 1-0 following a 2-0 home win at Estadio Azteca. We’ve seen four Cruz Azul wins, three Santos victories and three draws for the past 10 matches involving these teams.

Liga MX		G	W	D	L	GF	GA	GD	GD	P
5	Cruz Azul	4	2	2	0	9	5	4	9:5	8
7	Santos Laguna	4	2	0	2	6	5	1	6:5	6

View Full Table

6 wins, 1 loss and 3 draws, averaging 2.0 goals from 12.4 attempts and 6.0 shots on goal. Cruz Azul have had 55.6% possession and 5.6 corners per match. On average, the opposition have scored 1.3 goals from 7.4 attempts and 3.6 shots on goal, while earning 3.2 corners.

Angel Sepulveda is the top goalscorer with 5, Ignacio Rivero has 3, with Carlos Rodolfo Rotondi and two other players on 2. Jose Paradela and Carlos Rodolfo Rotondi are the top assists makers with 3.

Santos have won 2 and lost 8, with an average of 2.8 shots on goal, 7.6 attempts and 1.0 goals. Los Guerreros average 46.3% possession, 3.8 corners taken and 5.5 corners against them, while 2.1 goals have been conceded from 12.3 attempts and 5.0 shots on goal.

Bruno Barticciotto and Ramiro Sordo have top scored with 3 goals, while Jesus Ocejo is next on 1. Fran Villalba has been the top assist maker with 2 in the last 10 games.

Predicted & Confirmed Lineups

Cruz Azul predicted lineup (3-4-2-1): Kevin Mier (GK), Willer Ditta, Erik Lira, Gonzalo Piovi, Mateusz Bogusz, Ignacio Rivero, Carlos Rodriguez, Carlos Rodolfo Rotondi, José Antonio Paradela, Luka Romero, Angel Baltazar Sepulveda.

Santos Laguna predicted lineup (4-1-2-1-2): Carlos Acevedo Lopez (GK), José Javier Abella, Kevin Balanta, Bruno Amione, Emmanuel Echeverria, Javier Güemez, Aldo López Vargas, Fran Villalba, Jordan Carrillo, Bruno Barticciotto, Ramiro Sordo.

Cruz Azul vs Santos Laguna Prediction & Betting Tips

Be fully equipped for Cruz Azul vs Santos Laguna with our betting guide, offering a key match prediction, a correct score recommendation, valuable corners advice, top player prop picks and a bet builder tailored for value.

Match Prediction

We’re feeling bullish about Cruz Azul’s chances. Backing the favourites for this Liga MX game at -1.75 could be the way forward. There are attractive odds of -114 and we’re happy to take them.

We’re always aware of the injuries and suspensions for each team before we decide which way to go with our football picks. The form and data also help the Liga MX experts at Sportsgambler.com when it comes to a betting view on the action.

Key Cruz Azul vs Santos Laguna league stats:

• The +1.75 line hasn’t been covered by Santos in 3 of their last 5 games on the road.

Cruz Azul -1.75 Probability

Based on the odds from the best betting apps, our pick carries a 53.2% chance of winning. However, our research has found that the actual probability is closer to 60%. This bet can therefore be backed with confidence.

There’s an opportunity to secure bigger odds and this can be achieved by moving the line. Squeeze more juice from your pick by taking an alternative betting view.

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Our Match Prediction

Cruz Azul Asian Hcp -1.75 @ -114 Bet Now

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Correct Score Prediction

Cruz Azul 4 - 0 Santos

There are betting odds of +950 that Cruz Azul land a 4-0 victory. The correct score option is popular due to the potential return that can be achieved.

Player Prop Picks

Jose Ignacio Rivero Over 1.5 Shots On Target -125

Jose Ignacio Rivero (Cruz Azul) can be backed at -125 to cover the shots on goal total. All things considered, we think that the betting odds are really appealing when it comes to backing him on the Shots Target market.

Latest Jose Ignacio Rivero Player Prop Odds

Goalscorer

Anytime

+150

First

+420

Shots On Target

Over 1.5

-125

Under 1.5

-114

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Carlos Rodriguez to Score +475

Carlos Rodriguez (Cruz Azul) has managed two goals in his past five Liga MX games. We think this is the pick of the player props, with a generous +475 available when it comes to backing him to score at any time.

Latest Carlos Rodriguez Player Prop Odds

Goalscorer

Anytime

+475

First

+1200

Shots On Target

Over 0.5

+190

Under 0.5

-286

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Corners Prediction

Santos Under 2.5 Corners -110

In their past two matches, Santos have not covered the 2.5 corners line, with Cruz Azul conceding 2.80 corners on average in their last 5 games. For Team Corners, we’re expecting Santos to fall short and you can land odds of -110.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Cruz Azul

Total

8.80 5.60 3.20

Home

11.60 7.50 4.10

Away

9.60 4.30 5.30

Santos

Total

9.30 3.80 5.50

Home

10.30 4.70 5.60

Away

10.30 3.80 6.50

Latest Corner Odds

Total Corners

Over 9.5

-147

Under 9.5

-102

Cruz Azul Corners

Over 7.5

+110

Under 7.5

-150

Santos Corners

Over 2.5

-125

Under 2.5

-110

Most Corners

1

-588

X

+950

2

+525

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Cruz Azul vs Santos Laguna Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Betting Sites Running Scared of Cruz Azul Victory

Cruz Azul are convincing -435 favourites to land the spoils in this Liga MX encounter, which means a 81% likelihood of securing a victory according to the current betting odds. Santos Laguna are trading at a much larger price than their opponents and the outsiders can be backed at +900.

If you want to back the favourites to be ahead by the break, then Cruz Azul are -159 on the Half-Time Result market. Alternatively, Santos are +650 and the draw is priced at +180.

The Total Goals market indicates that Over 2.5 Goals is the betting favourite right now. If you’re looking to wager on Both Teams to Score, there’s not a lot of difference between Yes and No.

For those visiting one of our recommended sports betting sites, you are guaranteed a fantastic service for all the Liga MX matches. The hundreds of football markets always ensure lots of choice.

Full-Time Result

1

-435

X

+510

2

+900

Half-Time Result

1

-159

X

+180

2

+650

Double Chance

1X

-5000

12

-1250

X2

+240

Draw No Bet

1

-1429

2

+540

Asian Handicap

1 Hcp -1.75

-114

2 Hcp +1.75

-125

Total Goals

Under 2.5

+163

Over 2.5

-227

Both Teams to Score

Yes

-115

No

-123

Ángel Sepúlveda Favourite to Find the Net First

Ángel Sepúlveda is favourite to be First Goalscorer at +340, while you can get similar odds if you want him to score the last goal.

Ángel Sepúlveda (Cruz Azul)

First

-106

Anytime

+340

Giorgos Giakoumakis (Cruz Azul)

First

+145

Anytime

+420

Jose Ignacio Rivero (Cruz Azul)

First

+150

Anytime

+420

Gabriel Matías Fernández (Cruz Azul)

First

+155

Anytime

+450

Luka Romero (Cruz Azul)

First

+330

Anytime

+850

Bruno Barticciotto (Santos)

First

+380

Anytime

+1100

Carlos Rodolfo Rotondi (Cruz Azul)

First

+400

Anytime

+1050

Lorenzo Faravelli (Cruz Azul)

First

+475

Anytime

+1200

Carlos Rodriguez (Cruz Azul)

First

+475

Anytime

+1200

Ramiro Sordo (Santos)

First

+480

Anytime

+1200

Amaury García Moreno (Cruz Azul)

First

+500

Anytime

+1300

Cristian Jiménez (Cruz Azul)

First

+525

Anytime

+1300

Gonzalo Piovi (Cruz Azul)

First

+525

Anytime

+1400

Jordan Carrillo (Santos)

First

+600

Anytime

+1500

Fran Villalba (Santos)

First

+700

Anytime

+1800

Ronaldo Prieto (Santos)

First

+850

Anytime

+2200

Jorge Sánchez (Cruz Azul)

First

+850

Anytime

+2200

Diego Javier Medina Vázquez (Santos)

First

+850

Anytime

+2200

Cristian Dájome (Santos)

First

+850

Anytime

+2200

Giorgos Giakoumakis (Cruz Azul)

Over 0.5

-233

Under 0.5

+155

Gabriel Matías Fernández (Cruz Azul)

Over 0.5

-213

Under 0.5

+120

Jose Ignacio Rivero (Cruz Azul)

Over 1.5

-125

Under 1.5

-114

Bruno Barticciotto (Santos)

Over 0.5

+110

Under 0.5

-192

Luka Romero (Cruz Azul)

Over 0.5

+125

Under 0.5

-182

Carlos Rodolfo Rotondi (Cruz Azul)

Over 0.5

+135

Under 0.5

-200

Ángel Sepúlveda (Cruz Azul)

Over 1.5

+140

Under 1.5

-263

Ramiro Sordo (Santos)

Over 0.5

+155

Under 0.5

-227

Jordan Carrillo (Santos)

Over 0.5

+180

Under 0.5

-270

Carlos Rodriguez (Cruz Azul)

Over 0.5

+190

Under 0.5

-286

Lorenzo Faravelli (Cruz Azul)

Over 0.5

+190

Under 0.5

-294

Amaury García Moreno (Cruz Azul)

Over 0.5

+220

Under 0.5

-345

Fran Villalba (Santos)

Over 0.5

+240

Under 0.5

-385

Gonzalo Piovi (Cruz Azul)

Over 0.5

+245

Under 0.5

-400

Diego Javier Medina Vázquez (Santos)

Over 0.5

+280

Under 0.5

-476

Cristian Jiménez (Cruz Azul)

Over 0.5

+295

Under 0.5

-500

Cristian Dájome (Santos)

Over 0.5

+310

Under 0.5

-526

Ronaldo Prieto (Santos)

Over 0.5

+320

Under 0.5

-556

Jorge Sánchez (Cruz Azul)

Over 0.5

+340

Under 0.5

-625

Can Cruz Azul Continue Unbeaten Home Streak?

Cruz Azul are unbeaten in the last ten games at Estadio Azteca. La Máquina Celeste have racked up eight wins and two draws in the last 10 home matches, scoring an average of 1.80 goals per game and conceding 0.60.

Santos Laguna have suffered a five match losing run away from home. The Comarca Lagunera team have managed nine losses and one draw in the last 10 away matches, recording an average of 0.70 goals per game and conceding 2.00.

When the teams previously met at Estadio Azteca, Cruz Azul defeated Santos 2-0. Cruz Azul have won four of the previous 8 H2H games at Estadio Azteca, with Santos getting two victories along with two draws.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Cruz Azul Home Stats		8-2-0	2.40	1.80	0.60	5	5	5	5
Santos Laguna Away Stats		0-1-9	2.70	0.70	2.00	5	5	5	5

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

Cruz Azul vs Santos Laguna Lineups & Team News

Always review the Cruz Azul vs Santos team news before locking in your bets. We’ll keep you posted with predicted and confirmed lineups for the Liga MX and all current injury news.

Cruz Azul Team Page Santos Laguna Team Page