Genoa vs Empoli Prediction, Betting Tips, Lineups & Odds | 25 Sep 2025

Coppa Italia Betting Preview: Genoa vs Empoli

Serie A team Genoa host Serie B outfit Empoli in this Coppa Italia second round match, with kick-off set for 12:30 on Thursday 25 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats and team news.

Genoa should be able to beat Empoli by two goals or more. We’ll back them -1 at -116, meaning money back if the favourites claim a one goal victory, although we think the margin should be bigger.

Genoa were defeated on the road in their last game. Bologna won 2-1 at Stadio Renato Dell'Ara in Serie A. Il Grifone had 41% possession and totalled four shots on target, with Mikael Egill Ellertsson scoring the goal.

Empoli lost on the road in their previous game. Pescara won 4-0 at Stadio Adriatico Giovanni Cornacchia in Serie B. The Tuscany team had three shots on goal and enjoyed 56% possession.

In the first round, Genoa beat Serie C side Vicenza 3-0 at home, while Empoli won on penalties when hosting Serie B outfit Reggiana (1-1 after 90 mins).

Head-to-Head Statistics

Genoa have avoided defeat against Empoli in the past seven meetings, with their last encounter ending in a 1-1 Serie A draw at Stadio Luigi Ferraris. The previous 7 H2H games have featured five draws and two Genoa victories.

Serie A		G	W	D	L	GF	GA	GD	GD	P
13	Genoa	30	8	9	13	36	42	-6	36:42	33

Serie B		G	W	D	L	GF	GA	GD	GD	P
12	Empoli	32	8	12	12	43	47	-4	43:47	36

1 win, 6 losses and 3 draws, averaging 1.0 goals from 3.2 shots on goal and 8.0 attempts. Genoa have had 45.4% possession, 356.2 passes and 4.1 corners per game. On average, their opponents have scored 1.5 goals from 4.9 shots on goal and 12.9 attempts, while being awarded 6.1 corners.

Vitinha, Lorenzo Venturino and Andrea Pinamonti are joint-top scorers with 2 goals on the board. Aaron Martin Caricol is the leading assists maker with 4, while goalie Nicola Leali has one clean sheet.

Empoli have won 1, lost 2 and drawn 1, averaging 7.0 attempts, 3.8 shots on goal and 1.3 goals. Guido Pagliuca's side average 47.3% possession, 3.8 corners awarded and 6.3 corners against them, while 2.3 goals have been conceded from 6.3 shots on goal and 9.0 attempts.

Bohdan Popov has scored 4 goals, while Stiven Shpendi has 1. Salvatore Elia has managed to clock up 2 assists in the last 4 games.

Confirmed Lineups

Genoa confirmed lineup (4-2-3-1): Nicola Leali (GK), Stefano Sabelli, Alessandro Marcandalli, Johan Vasquez, Aaron Martin Caricol, Nicolae Stanciu, Morten Frendrup, Valentin Carboni, Junior Messias, Albert Groenbaek, Lorenzo Colombo.

Empoli confirmed lineup (3-4-3): Samuele Perisan (GK), Tyronne Ebuehi, Gabriele Guarino, Nosa Edward Obaretin, Brando Moruzzi, Luca Belardinelli, Gerard Yepes, Franco Carboni, Rares Ilie, Bogdan Popov, Edoardo Saporiti.

Genoa vs Empoli Prediction & Betting Tips

Get the edge with our Genoa vs Empoli betting tips: our expert match prediction, most likely correct score outcome and a bet builder tailored for value.

Match Prediction

The best Asian Handicap bet could be Genoa -1 at -116, especially if you think that they can win handsomely. We are expecting the favourites to dominate when it comes to this Coppa Italia encounter.

In order to come up with the best football predictions, we like to know the Coppa Italia team news and study the latest form. There are also plenty of numbers to crunch from the available stats.

Key Genoa vs Empoli Coppa Italia & league stats:

• The +1 line hasn’t been covered by Empoli in 3 of their last 5 games on the road.
• The +1 line hasn’t been covered by Empoli in 2 consecutive games on the road.

According to the latest betting odds, our pick has a 53.8% chance of winning. In our opinion, there’s actually a probability of success closer to 60%. This is why we can recommend this wager.

Placing a Bet Builder is a recommended option if you want to bet on Genoa to cover the line but want more juice from your wager. Choose the various legs that you want to add in.

Make your bet count—our comprehensive bonus guide highlights the latest free bets and betting promo codes worth grabbing.

Our Match Prediction

Genoa Asian Hcp -1 @ -116 Bet Now

BetMGM Promo Up To $1500 in Bonus Bets Get Bonus T&C apply. Gamble responsibly 18+

Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Sep 23, 18:37). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Genoa 2 - 0 Empoli

Our prediction for the correct score is Genoa to land a 2-0 victory and this is available at +400. It’s a fun wager to place which lands a bigger potential return.

Genoa vs Empoli Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

With the bookies giving them a 70% probability of winning, Genoa might be a popular acca pick. Their current betting odds are -233 when it comes to triumphing in this Coppa Italia clash. If you want to back the outsider, Empoli are available at +700.

You can take advantage of the Half-Time Result market if you think a team will lead at the break. There's the chance to back Genoa at -100, go for Empoli at +600 or take the draw at +128.

Under 2.5 Goals is a short-priced option for those expecting two goals or less. Both Teams to Score No is available at -192 for anyone expecting at least one side to draw a blank.

The top sports betting sites provide a quality service including hundreds of markets being created for every Coppa Italia game. It’s great for football bettors to choose from so many options.

Full-Time Result

1

-233

X

+325

2

+700

Half-Time Result

1

-100

X

+128

2

+600

Double Chance

1X

-1429

12

-556

X2

+160

Draw No Bet

1

-833

2

+420

Asian Handicap

1 Hcp -1.25

-103

2 Hcp +1.25

-132

Total Goals

Under 2.5

-139

Over 2.5

+107

Both Teams to Score

Yes

+132

No

-192

Favourite Lorenzo Colombo is available at +330 to be the First Goalscorer. Similar odds apply if you’re interested in him to score the last goal.

Lorenzo Colombo (Genoa)

First

+148

Anytime

+330

Junior Messias (Genoa)

First

+220

Anytime

+480

Vitor Oliveira "Vitinha" (Genoa)

First

+235

Anytime

+500

Ruslan Malinovskyi (Genoa)

First

+270

Anytime

+550

Nicolae Stanciu (Genoa)

First

+295

Anytime

+650

Albert Gronbaek (Genoa)

First

+300

Anytime

+650

Seydou Fini (Genoa)

First

+350

Anytime

+700

Mikael Egill Ellertsson (Genoa)

First

+400

Anytime

+850

Morten Frendrup (Genoa)

First

+480

Anytime

+1000

Patrizio Masini (Genoa)

First

+575

Anytime

+1200

Johan Vásquez (Genoa)

First

+850

Anytime

+1700

Stefano Sabelli (Genoa)

First

+900

Anytime

+2000

Latest Coppa Italia and domestic league stats. Full Time Result, Goals, Corners and Possession.

Genoa Stats

Empoli Stats

Full-Time Result

• 1 win, 6 defeats and 3 draws in the previous 10 matches
• 4 wins, 4 defeats and 2 draws in the previous 10 home matches

Full-Time Result

• 1 win, 2 defeats and 1 draw in the previous 4 matches
• 2 defeats have been inflicted in the previous 2 away matches.

Goals

• An average of 1.00 goals scored and 1.50 conceded in the previous 10 matches
• An average of 1.10 goals scored and 1.00 conceded in the previous 10 home matches
• An average of 2.50 goals per game in the previous 10 matches
• An average of 2.10 goals per game in the previous 10 home matches
• BTTS Yes in 6 of the previous 10 matches
• BTTS Yes in 4 of the previous 10 home matches
• Over 2.5 Goals in 5 of the previous 10 matches
• Over 2.5 Goals in 3 of the previous 10 home matches

Goals

• An average of 1.25 goals scored and 2.25 conceded in the previous 4 matches
• An average of 0.50 goals scored and 3.50 conceded in the previous 2 away matches
• An average of 3.50 goals per game in the previous 4 matches
• An average of 4.00 goals per game in the previous 2 away matches
• BTTS Yes in 3 of the previous 4 matches
• BTTS Yes in 1 of the previous 2 away matches
• Over 2.5 Goals in 3 of the previous 4 matches
• Over 2.5 Goals in 2 of the previous 2 away matches

Corners

• An average of 4.10 corners awarded and 6.10 corners conceded in the last 10 matches
• An average of 4.70 corners awarded and 4.80 corners against in the last 10 home matches
• An average of 10.20 corners awarded in the last 10 matches
• An average of 9.50 corners awarded in the last 10 home matches
• Had the most corners in 3 and least corners in 7 of the last 10 matches
• Had the most corners in 3 and least corners in 6 of the last 10 home matches

Corners

• An average of 3.75 corners awarded and 6.25 corners conceded in the last 4 matches
• An average of 3.50 corners awarded and 7.00 corners against in the last 2 away matches
• An average of 10.00 corners awarded in the last 4 matches
• An average of 10.50 corners awarded in the last 2 away matches
• Had the most corners in 1 and least corners in 3 of the last 4 matches
• Had the most corners in 0 and least corners in 2 of the last 2 away matches

Possession

• An average of 45.40% possession in the last 10 matches
• An average of 49.60% possession in the last 10 home matches
• Most possession in 2 of the last 10 matches
• Most possession in 5 of the last 10 home matches

Possession

• An average of 47.25% possession in the last 4 matches
• An average of 47.50% possession in the last 2 away matches
• Most possession in 2 of the last 4 matches
• Most possession in 1 of the last 2 away matches

Genoa vs Empoli Lineups & Team News

Before placing any bets on Genoa vs Empoli, check the team news first. We’ll provide the confirmed lineups for the Coppa Italia plus the latest injury updates.

Top Football Pages