Guadalajara vs Santos Laguna Prediction, Betting Tips, Lineups & Odds | 14 Mar 2026

Liga MX Betting Preview: Guadalajara vs Santos Laguna

Guadalajara square off against Santos Laguna at Estadio Akron, with kick-off set for 19:07 on Saturday 14 March.

We think Guadalajara can land a big win against Santos Laguna. We’ll back them -2 on the Asian Handicap at odds of -122 which means money back if the favourites triumph by two and a full return if the winning margin is bigger.

Guadalajara have now achieved three straight home victories. In their last game, they won on their travels at Estadio Jalisco when beating Atlas 2-1. They recorded an incredible 77% of possession and had three shots on target, while Armando Gonzalez and Angel Sepulveda scored one goal apiece.

Santos Laguna won their previous game. It was on the road where Club Tijuana were beaten 2-1 at Estadio Caliente. Omar Tapia's team recorded 45% possession and totalled nine shots on goal, while Ezequiel Bullaude and Jesus Ocejo were on the scoresheet.

Head-to-Head Statistics

These two teams last met at Estadio Nuevo Corona, with Santos claiming the home win. Beating Guadalajara by a 1-0 scoreline. Guadalajara have landed four victories, Santos have two wins and there’s been four draws in the past 10 H2H meetings.

Liga MX		G	W	D	L	GF	GA	GD	GD	P
3	Guadalajara	9	7	0	2	14	9	5	14:9	21
18	Santos Laguna	10	1	2	7	12	26	-14	12:26	5

View Full Table

7 wins and 3 losses, averaging 1.6 goals from 4.6 shots on goal and 11.1 attempts. Chivas have had 58.8% possession and 4.5 corners per game. On average, they have conceded 1.2 goals from 3.0 shots on goal and 6.5 attempts, while their opponents have been awarded 2.6 corners.

Top scorer is Armando Gonzalez on 6 goals, while Angel Sepulveda and Daniel Aguirre have both racked up 2. Roberto Alvarado has made the most assists with 3.

Santos have won 1, lost 7 and drawn 2, averaging 8.4 attempts, 4.0 shots on goal and 1.2 goals. Los Guerreros average 45.9% possession, 4.3 corners awarded and 3.8 corners against them, while 2.6 goals have been conceded from 6.1 shots on goal and 11.8 attempts.

Ezequiel Bullaude and Lucas Di Yorio have top scored with 4 goals, while Fran Villalba is next on 2. Lucas Di Yorio and Ramiro Sordo have been the top assists providers with 2 in the last 10 games.

Predicted & Confirmed Lineups

Guadalajara predicted lineup (3-4-2-1): José Raúl Rangel (GK), Diego Campillo, Armando González, José Castillo, Richard Ledezma, Fernando González, Daniel Aguirre, Bryan González, Omar Govea, Angel Baltazar Sepulveda, Roberto Alvarado.

Santos Laguna predicted lineup (4-2-3-1): Carlos Acevedo Lopez (GK), Kevin Picón, Kevin Balanta, Bruno Amione, Emmanuel Echeverria, Carlos Gruezo, Javier Güemez, Fran Villalba, Ezequiel Bullaude, Luis Gómez, Lucas Di Yorio.

Guadalajara vs Santos Laguna Prediction & Betting Tips

Join us as we dissect the top Guadalajara vs Santos Laguna betting picks — from the main match prediction and scoreline forecast to a sharp corners bet, standout player props and a value-focused bet builder.

Match Prediction

Backing Guadalajara -2 at -122 could provide a nice return. There’s some insurance in this bet although we think this Liga MX clash will be a one-sided affair and the price looks attractive.

Injuries and suspensions are studied by the team at Sportsgambler.com. Our football predictions also come from studying the latest Liga MX form, with the numbers playing a huge part before the tips are decided.

Key Guadalajara vs Santos Laguna league stats:

• The +2 line hasn’t been covered by Santos in 5 of their last 10 games on the road.

The best football bookies are estimating that there is a 54.9% likelihood of this pick landing a return. After careful examination, our tipsters have this probability close to 60%. This wager can therefore be backed with confidence.

There’s an opportunity to land bigger odds thanks to selling goals on your Asian Handicap wager. If you want a safer wager, buying goals could be the way forward.

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Our Match Prediction

Guadalajara Asian Hcp -2 @ -122 Watch Live Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Mar 13, 01:28). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Guadalajara 3 - 0 Santos

We’ve got a correct score prediction which involves Guadalajara winning 3-0. Odds of +575 look appealing and we should get a run for our money here.

Player Prop Picks

Top Pick: Roberto Alvarado to Score +155

Roberto Alvarado (Guadalajara) has racked up two goals in his past five Liga MX matches on home soil. We believe that there is merit in backing him for an Anytime Goalscorer prop wager at +155 which means we need to him to be on the scoresheet.

Latest Roberto Alvarado Player Prop Odds

Goalscorer

Anytime

+155

First

+500

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Corners Prediction

Guadalajara Under 7.5 Corners -141

The 7.5 corners line has not been covered by Guadalajara in their past ten games, with the corner count against Santos going under 7.5 in their last ten matches. There are odds of -141 for this Guadalajara Team Corners wager and we think the line is too high.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Guadalajara

Total

7.10 4.50 2.60

Home

8.90 5.10 3.80

Away

7.00 4.40 2.60

Santos

Total

8.10 4.30 3.80

Home

9.50 4.40 5.10

Away

10.00 4.10 5.90

Latest Corner Odds

Total Corners

Over 10.5

-118

Under 10.5

-127

Guadalajara Corners

Over 7.5

-111

Under 7.5

-141

Santos Corners

Over 2.5

-147

Under 2.5

-108

Most Corners

1

-714

X

+1000

2

+540

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Guadalajara vs Santos Laguna Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

With an estimated 85% chance of winning, the bookies are taking few chances with their -588 betting odds about Guadalajara triumphing in this Liga MX clash. Santos Laguna are operating at larger odds than the opposition and the underdogs can be wagered at +1200.

As the name suggests, the Half-Time Result market is settled at the break. Should you take this option, then you can choose between Guadalajara at -204, Santos at +750 or the draw at +210.

You can find the shortest odds for Over 2.5 Goals, which means three goals or more being scored. BTTS Yes is available at -130 for anyone expecting Both Teams to Score.

Liga MX games are always really well covered at the top betting sites. Customers are able to find a suitable betting angle thanks to the hundreds of football markets which are made available.

Full-Time Result

1

-588

X

+600

2

+1200

Half-Time Result

1

-204

X

+210

2

+750

Draw No Bet

1

-10000

2

+800

Asian Handicap

1 Hcp -2

-122

2 Hcp +2

-105

Total Goals

Under 2.5

+215

Over 2.5

-333

Both Teams to Score

Yes

-130

No

-115

Armando González is favourite to be First Goalscorer at +225. If you want to back him to score the last goal, you can get similar odds.

Armando González (Guadalajara)

First

-192

Anytime

+225

Ángel Sepúlveda (Guadalajara)

First

-105

Anytime

+340

Ricardo Marin (Guadalajara)

First

+120

Anytime

+410

Jonathan Pérez (Guadalajara)

First

+150

Anytime

+480

Roberto Alvarado (Guadalajara)

First

+155

Anytime

+500

Efrain Alvarez (Guadalajara)

First

+170

Anytime

+575

Brian Gutierrez (Guadalajara)

First

+200

Anytime

+650

Omar Govea (Guadalajara)

First

+210

Anytime

+700

Richard Ledezma (Guadalajara)

First

+250

Anytime

+800

Bryan Gonzalez (Guadalajara)

First

+250

Anytime

+850

Ramiro Sordo (Santos)

First

+400

Anytime

+1400

Gilberto Sepulveda (Guadalajara)

First

+450

Anytime

+1500

Lucas Di Yorio (Santos)

First

+475

Anytime

+1600

Fernando González (Guadalajara)

First

+510

Anytime

+1700

Daniel Aguirre (Guadalajara)

First

+550

Anytime

+1800

Fran Villalba (Santos)

First

+550

Anytime

+1900

Ezequiel Bullaude (Santos)

First

+600

Anytime

+2200

Guadalajara are unbeaten in the last eight games at Estadio Akron. They have seven wins, two draws and one loss in the last 10 home games, scoring an average of 1.80 goals per match and conceding 0.80.

Santos have recorded seven losses, two draws and one win in the previous 10 away games, scoring an average of 1.00 goals per match and conceding 2.70.

Guadalajara won 1-0 when they last played Santos at Estadio Akron. There have been two draws in the previous 5 H2H matches at Estadio Akron along with three Guadalajara victories.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Guadalajara Home Stats		7-2-1	2.60	1.80	0.80	5	5	4	6
Santos Laguna Away Stats		1-2-7	3.70	1.00	2.70	9	1	7	3

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

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Guadalajara vs Santos Laguna Lineups & Team News

Be prepared — check the Chivas vs Santos team news before wagering. We’ll share both predicted and confirmed lineups for the Liga MX along with the latest injury news.

Guadalajara Team Page Santos Laguna Team Page

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