Lille vs Lyon Prediction, Betting Tips, Lineups & Odds | 28 Sep 2025

Ligue 1 Betting Preview: Lille vs Lyon

Lille host Lyon in this French Ligue 1 meeting at Stade Pierre-Mauroy, with kick-off set for 11:15 on Sunday 28 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

We think there’s a good angle when it comes to Over 2.5 for the clash between Lille and Lyon. Our opinion is that the Total Goals market affords great value and we will snap up the -141 on offer.

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LOSC Lille have landed back-to-back Ligue 1 home victories. In their last league game, it was a 3-0 road defeat against RC Lens at Stade Bollaert-Delelis. Bruno Genesio's team had the majority of the ball enjoying 62% possession and three shots on target.

On Thursday night, Lille secured a 2-1 Europa League victory at home to Brann.

Lyon won their previous Ligue 1 game, beating Angers at home. It was a 1-0 win at Parc Olympique Lyonnais. The Auvergne-Rhône-Alpes club enjoyed 67% possession and managed five shots on goal, with Tanner Tessmann scoring the winner in the 65th minute.

Last time out, Lyon claimed a 1-0 victory when facing FC Utrecht away in the Europa League.

Head-to-Head Statistics

Lyon haven’t lost to Lille in their past four games. Their last encounter saw Lyon make home advantage count at Parc Olympique Lyonnais, winning 2-1. The past 10 H2H games have featured four triumphs for Lyon, two for Lille and four draws.

Ligue 1		G	W	D	L	GF	GA	GD	GD	P
4	Lyon	19	11	3	5	32	20	12	32:20	36
5	Lille	19	10	2	7	34	29	5	34:29	32

View Full Table

6 wins, 2 losses and 2 draws, averaging 2.1 goals from 4.8 shots on goal and 14.6 attempts. Lille have had 59.6% possession, 522.5 passes and 6.4 corners per game. On average, they have conceded 1.3 goals from 3.5 shots on goal and 9.4 attempts, while the opposition have been awarded 4.0 corners.

Top scorers are Matias Fernandez-Pardo and Hakon Arnar Haraldsson on 3 goals, while Hamza Igamane has racked up 2. Felix Correia is the leading assists maker with 3, while goalkeepers Berke Ozer and Lucas Chevalier collectively have 2 clean sheets.

Lyon have won 6 and lost 4, with an average of 1.5 goals from 14.1 attempts and 4.6 shots on goal. Paulo Fonseca's team average 56.4% possession, 469.9 passes, 6.6 corners awarded and 5.2 corners against them, while conceding 1.0 goals from 12.6 attempts and 3.7 shots on goal.

Corentin Tolisso, Georges Mikautadze and Alexandre Lacazette have scored 3 goals, followed by Tanner Tessmann with 2. Ainsley Maitland-Niles leads the way with 3 assists, while Remy Descamps, Lucas Perri and Dominik Greif have notched 5 clean sheets between them in the previous 10 games.

Confirmed Lineups

Lille confirmed lineup (4-2-3-1): Arnaud Bodart (GK), Aissa Mandi, Nathan Ngoy, Tiago Santos, Calvin Verdonk, Ngal Ayel Mukau, Ayyoub Bouaddi, Felix Correia, Hakon Arnar Haraldsson, Matias Fernandez-Pardo, Olivier Giroud.

Lyon confirmed lineup (4-2-3-1): Dominik Greif (GK), Ainsley Maitland-Niles, Clinton Mata, Moussa Niakhate, Nicolas Tagliafico, Tyler Morton, Tanner Tessmann, Adam Karabec, Corentin Tolisso, Malick Fofana, Khalis Merah.

Lille vs Lyon Prediction & Betting Tips

We bring you the complete Lille vs Lyon betting insight, including our top match prediction, correct score forecast, player prop advice and a ready-made bet builder.

Match Prediction

This upcoming encounter could yield Over 2.5 Goals and we’re keen to back this Ligue 1 prediction. There is plenty of value when it comes betting this selection at odds of -141.

The form guide is always considered and it’s great to also use the Ligue 1 team news as it filters through ahead of kick-off. In our quest for the best possible football predictions, the latest stats are scrutinised so that we have the best data.

Key Lille vs Lyon league stats:

• The 2.5 line has been covered in 4 of the last 5 Lille games.
• The 2.5 line has been covered in 11 of the last 18 Lille games at home.
• The 2.5 line has been covered in the last 3 Lille games.
• The 2.5 line has been covered in 14 of the last 20 OL games.
• The 2.5 line has been covered in 11 of the last 18 OL games on the road.

The betting odds at the top bookies suggest our pick carries a 58.5% chance of winning. In our opinion, there’s actually a probability of success between 65-70%. This is why we regard this as a value wager.

There are alternatives to this betting selection including Over 3.5 Goals where bettors can land bigger odds. You need four or more to be scored in order to trigger a pay out with this pick.

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Our Match Prediction

Over 2.5 Goals @ -141 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (17:37, 26 September 2025). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Lille 2 - 1 Lyon

An exciting bet could be a 2-1 victory in favor of Lille at odds of +750. A correct score wager provides a fun alternative and a nice potential return on the cards.

Player Prop Picks

Top Pick: Olivier Giroud Over 3.5 Shots +107

Olivier Giroud (Lille) has recorded over 3.5 shots in three of his past four Ligue 1 matches. It certainly looks possible that he will cover the Player Shots line and there are odds of +107 up for grabs.

Latest Olivier Giroud Player Prop Odds

Goalscorer

Anytime

+138

First

+390

Shots

Over 3.5

+107

Under 3.5

-

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Matias Fernandez-Pardo to Score +310

Matias Fernandez-Pardo (Lille) has registered two goals in his past five Ligue 1 games. He looks like an attractive wager to be on the scoresheet and you’re able to back this Anytime Goalscorer selection at odds of +310.

Latest Matias Fernandez-Pardo Player Prop Odds

Goalscorer

Anytime

+310

First

+700

Shots

Over 1.5

-164

Under 1.5

-

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Lille vs Lyon Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The bookies have LOSC Lille at +128 when it comes to Full-Time Result. This implies that the favourites are 44% likely to win this Ligue 1 encounter according to the latest betting odds. Lyon are trading at a bigger price than their opponents and the outsiders can be backed at +205.

There are different betting angles when backing Lille including the Asian Handicap -0.25 wager. This is available at -104 and there’s a half stake return if they only draw with Lyon.

Over 2.5 Goals is available at shorter odds than Under 2.5 Goals as things stand. An alternative angle is a Both Teams to Score bet and Yes has been chalked up at -175.

The best football betting sites have excellent coverage for the latest Ligue 1 games. They supply customers with hundreds of markets and it’s down to you to find the best angle.

Full-Time Result

1

+128

X

+250

2

+205

Half-Time Result

1

+175

X

+128

2

+235

Double Chance

1X

-286

12

-357

X2

-172

Draw No Bet

1

-159

2

+116

Asian Handicap

1 Hcp -0.25

-104

2 Hcp +0.25

-119

Total Goals

Under 2.5

+110

Over 2.5

-137

Both Teams to Score

Yes

-175

No

+128

Those interested in Olivier Giroud to find the net anytime can get +138, with the favourite on offer to score the first goal at odds of +390.

Olivier Giroud (Lille)

First

+138

Anytime

+390

Hamza Igamane (Lille)

First

+220

Anytime

+550

Corentin Tolisso (OL)

First

+280

Anytime

+650

Alejandro Jesús Gomes Rodríguez (OL)

First

+290

Anytime

+650

Malick Fofana (OL)

First

+300

Anytime

+700

Matias Fernandez-Pardo (Lille)

First

+310

Anytime

+700

Félix Correia (Lille)

First

+350

Anytime

+800

Pavel Sulc (OL)

First

+350

Anytime

+850

Enzo Molébé (OL)

First

+380

Anytime

+850

Marius Sivertsen Broholm (Lille)

First

+380

Anytime

+950

Hákon Haraldsson (Lille)

First

+390

Anytime

+1000

Osame Sahraoui (Lille)

First

+480

Anytime

+1200

Afonso Bastardo Moreira (OL)

First

+480

Anytime

+1050

Rachid Ghezzal (OL)

First

+480

Anytime

+1050

Adam Karabec (OL)

First

+500

Anytime

+1200

Khalis Merah (OL)

First

+650

Anytime

+1500

Ainsley Maitland-Niles (OL)

First

+700

Anytime

+1600

Mathys de Carvalho Soares (OL)

First

+750

Anytime

+1900

Tyler Morton (OL)

First

+750

Anytime

+1900

Tanner Tessmann (OL)

First

+750

Anytime

+1900

Chancel Mbemba (Lille)

First

+900

Anytime

+2000

Tiago Santos (Lille)

First

+900

Anytime

+2000

Ayyoub Bouaddi (Lille)

First

+950

Anytime

+2200

Nathan Ngoy (Lille)

First

+950

Anytime

+2200

Olivier Giroud (Lille)

Over 3.5

+107

Under 3.5

-

Hamza Igamane (Lille)

Over 2.5

-115

Under 2.5

-

Corentin Tolisso (OL)

Over 2.5

+145

Under 2.5

-

Alejandro Jesús Gomes Rodríguez (OL)

Over 1.5

-159

Under 1.5

-

Malick Fofana (OL)

Over 1.5

-175

Under 1.5

-

Matias Fernandez-Pardo (Lille)

Over 1.5

-164

Under 1.5

-

Félix Correia (Lille)

Over 1.5

-133

Under 1.5

-

Pavel Sulc (OL)

Over 1.5

-110

Under 1.5

-

Enzo Molébé (OL)

Over 1.5

+105

Under 1.5

-

Marius Sivertsen Broholm (Lille)

Over 1.5

+105

Under 1.5

-

Hákon Haraldsson (Lille)

Over 1.5

-108

Under 1.5

-

Adam Karabec (OL)

Over 1.5

+160

Under 1.5

-

Tanner Tessmann (OL)

Over 1.5

+130

Under 1.5

-

Ainsley Maitland-Niles (OL)

Over 0.5

-143

Under 0.5

-

Tiago Santos (Lille)

Over 0.5

-137

Under 0.5

-

Nathan Ngoy (Lille)

Over 0.5

-100

Under 0.5

-

Lille vs Lyon Lineups & Team News

Be prepared — check the Lille vs OL team news before wagering. We’ll have the predicted and confirmed Ligue 1 lineups for you plus all the latest on player injuries.

LOSC Lille Team Page Olympique Lyonnais Team Page

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