Manchester United vs Chelsea Prediction, Betting Tips, Lineups & Odds | 20 Sep 2025

Premier League Betting Preview: Manchester United vs Chelsea

Manchester United host Chelsea in this Premier League meeting at Old Trafford, with kick-off set for 12:30 on Saturday 20 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

Our Asian Handicap pick is Chelsea 0.0 and that means money back if the game finishes all square. We can secure odds of -135 that the Blues overcome Ruben Amorim's Man United and we’re confident when it comes to this wager.

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With four points from their opening four league encounters, Manchester United have endured their worst start to a Premier League season since 1992/93. United’s most recent outing ended in a 3-0 derby defeat on the road to Manchester City at the Etihad Stadium. The Red Devils enjoyed 55% possession and had two shots on target.

Chelsea played Brentford on the road in their previous Premier League game. It was a 2-2 draw at Gtech Community Stadium. Enzo Maresca's side boasted 67% possession and had six shots on goal, with Cole Palmer and Moises Caicedo both on target.

Three days ago, Chelsea were defeated 3-1 away to Bayern Munich in the Champions League.

Head-to-Head Statistics

Chelsea are unbeaten in the past three games against United. In the last clash, Chelsea secured a 1-0 win when hosting at Stamford Bridge. The past 10 H2H matches have witnessed six draws along with two wins each.

Premier League		G	W	D	L	GF	GA	GD	GD	P
4	Man United	23	10	8	5	41	34	7	41:34	38
5	Chelsea	23	10	7	6	39	25	14	39:25	37

View Full Table

2 wins, 6 losses and 2 draws, averaging 1.0 goals from 17.0 attempts and 4.7 shots on goal. United have had 57.1% possession, 487.8 passes and 5.6 corners per match. On average, the opposition have scored 1.6 goals from 8.9 attempts and 3.2 shots on goal, while earning 4.5 corners.

Top goalscorer Amad has found the net 2 times, with Bruno Fernandes, Bryan Mbeumo, Christian Eriksen and Mason Mount scoring 1 each. Manuel Ugarte is the top assists maker on 2, with goalie Altay Bayindir managing one clean sheet.

Chelsea have 7 victories, 1 defeat and 2 draws, with an average of 5.2 shots on goal, 12.6 attempts and 1.7 goals. The West London club average 55.4% possession, 485.7 passes, 6.4 corners taken and 4.1 corners against them, while 0.7 goals have been conceded from 9.2 attempts and 2.9 shots on goal.

Enzo Fernandez has scored 3 goals, followed by Cole Palmer, Moises Caicedo, Joao Pedro and Pedro Neto on 2. Joao Pedro and Enzo Fernandez have managed 3 assists in the last 10 games, while Robert Sanchez has 5 clean sheets to his name.

Confirmed Lineups

Manchester United confirmed lineup (4-4-2): Altay Bayindir (GK), Matthijs de Ligt, Harry Maguire, Luke Shaw, Noussair Mazraoui, Casemiro, Bruno Fernandes, Patrick Dorgu, Bryan Mbeumo, Amad, Benjamin Sesko.

Chelsea confirmed lineup (4-2-3-1): Robert Sanchez (GK), Reece James, Wesley Fofana, Trevoh Chalobah, Marc Cucurella, Enzo Fernandez, Moises Caicedo, Pedro Neto, Cole Palmer, Estevao, Joao Pedro.

Manchester United vs Chelsea Prediction & Betting Tips

Our Manchester United vs Chelsea tips include the main match prediction, a correct score forecast, a corners recommendation, bet builder advice and top player prop picks. Each section below offers expert insight into the key betting angles.

Match Prediction

Chelsea at 0.0 could be the way forward for this Premier League encounter. The Asian Handicap odds of -135 makes lots of appeal, with our betting prediction looking like a value wager.

The Premier League tipsters at Sportsgambler.com always have a strong handle on team news. A form guide is also utilised for our betting verdict along with checking out the numbers that are going to help inform our final football picks.

Key Manchester United vs Chelsea league stats:

• The 0.0 line has been covered by Chelsea in 7 of their last 10 games.
• The 0.0 line has been covered by Chelsea in 3 of their last 5 games.
• The 0.0 line hasn’t been covered by United in 8 of their last 10 games.
• The 0.0 line hasn’t been covered by United in 15 of their last 20 games.
• The 0.0 line hasn’t been covered by United in 8 of their last 10 games against Chelsea.

The best betting apps make it a 57.5% chance that our pick is settled as a winner. After careful examination, our experts calculate this probability to be somewhere between 60-65%. This bet can therefore be backed with confidence.

There’s the option to bet on Chelsea to triumph by a specific number of goals through the Winning Margin market. This offers an attractive Asian Handicap alternative.

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Our Match Prediction

Chelsea Asian Hcp 0.0 @ -135 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (18:38, 18 September 2025). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Man United 1 - 2 Chelsea

Chelsea are available to back at +750 to secure a 2-1 victory. This is a risky but potentially more rewarding bet, with this correct score option providing appeal.

Player Prop Picks

Top Pick: Pedro Neto Over 1.5 Shots -125

Pedro Neto (Chelsea) has fired over 1.5 shots in eight of his past nine Premier League away games. There is odds of -125 on offer for this Player Shots wager and we think he’ll cover the line.

Latest Pedro Neto Player Prop Odds

Goalscorer

Anytime

+350

First

+900

Shots On Target

Over 0.5

-103

Under 0.5

-164

Shots

Over 1.5

-120

Under 1.5

-

---

João Pedro To Score +155

João Pedro (Chelsea) is available at +155 to be on the scoresheet. We think this is the pick of the player props, with generous odds available when it comes to backing him to score at any time.

Latest João Pedro Player Prop Odds

Goalscorer

Anytime

+170

First

+450

Shots On Target

Over 0.5

-233

Under 0.5

+133

Shots

Over 2.5

-111

Under 2.5

-

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Corners Prediction

Over 9.5 Corners -143

There has been five consecutive Chelsea games where 9.5 Total Corners has been covered, while it has been an average of 10.10 corners in the last ten United matches. The Total Corners line looks attractive and we’re going to take the -143 that it’s covered.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Man United

Total

10.10 5.60 4.50

Home

9.30 5.80 3.50

Away

11.70 5.40 6.30

Chelsea

Total

10.50 6.40 4.10

Home

10.90 7.60 3.30

Away

9.10 5.20 3.90

Latest Corner Odds

Total Corners

Over 9.5

-147

Under 9.5

+104

Man United Corners

Over 4.5

-125

Under 4.5

-110

Chelsea Corners

Over 5.5

+120

Under 5.5

-163

Most Corners

1

+110

X

+600

2

+104

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Manchester United vs Chelsea Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The bookmakers have priced up the Full-Time Result odds and Chelsea are +148 to come out on top, while Manchester United are +165. The draw is available at +265 if you expect the clash to finish level.

There’s a nice alternative in the form of the Half-Time Result market. This allows you to back Chelsea at +188 to lead at the break or alternatively opt for United at +205. The draw is the third option at +145.

The Total Goals market indicates that Over 2.5 Goals is the betting favourite right now. Should you expect both teams score, then the BTTS Yes option is available at -217.

The best football betting sites have excellent coverage for the latest Premier League games. They supply customers with hundreds of markets and it’s down to you to find the best angle.

Full-Time Result

1

+165

X

+265

2

+148

Half-Time Result

1

+205

X

+145

2

+188

Double Chance

1X

-192

12

-357

X2

-213

Draw No Bet

1

-109

2

-125

Asian Handicap

1 Hcp +0.25

-143

2 Hcp -0.25

+114

Total Goals

Under 2.5

+143

Over 2.5

-185

Both Teams to Score

Yes

-217

No

+155

There’s the chance to back Cole Palmer at +400 to be the First Goalscorer, with the favourite on this market available at similar odds to find the net last.

Cole Palmer (Chelsea)

First

+138

Anytime

+400

Benjamin Sesko (United)

First

+155

Anytime

+430

João Pedro (Chelsea)

First

+170

Anytime

+450

Bryan Mbeumo (United)

First

+175

Anytime

+475

Matheus Cunha (United)

First

+190

Anytime

+500

Bruno Fernandes (United)

First

+190

Anytime

+525

Alejandro Garnacho (Chelsea)

First

+300

Anytime

+750

Joshua Zirkzee (United)

First

+300

Anytime

+750

Estêvão Willian Gonçalves (Chelsea)

First

+300

Anytime

+800

Pedro Neto (Chelsea)

First

+350

Anytime

+900

Amad Diallo (United)

First

+350

Anytime

+900

Facundo Buonanotte (Chelsea)

First

+380

Anytime

+900

Jamie Bynoe-Gittens (Chelsea)

First

+380

Anytime

+950

Tyrique George (Chelsea)

First

+500

Anytime

+1150

Enzo Fernández (Chelsea)

First

+510

Anytime

+1400

Mason Mount (United)

First

+600

Anytime

+1400

Andrey Nascimento dos Santos (Chelsea)

First

+600

Anytime

+1500

Carlos Casemiro (United)

First

+600

Anytime

+1600

Kobbie Mainoo (United)

First

+650

Anytime

+1700

Patrick Dorgu (United)

First

+750

Anytime

+1900

Marc Cucurella (Chelsea)

First

+900

Anytime

+2200

Benjamin Sesko (United)

Over 0.5

-250

Under 0.5

+140

Matheus Cunha (United)

Over 0.5

-250

Under 0.5

+155

João Pedro (Chelsea)

Over 0.5

-233

Under 0.5

+133

Cole Palmer (Chelsea)

Over 0.5

-208

Under 0.5

+120

Bruno Fernandes (United)

Over 0.5

-204

Under 0.5

+128

Alejandro Garnacho (Chelsea)

Over 0.5

-139

Under 0.5

-112

Estêvão Willian Gonçalves (Chelsea)

Over 0.5

-125

Under 0.5

-135

Joshua Zirkzee (United)

Over 0.5

-111

Under 0.5

-139

Amad Diallo (United)

Over 0.5

-105

Under 0.5

-147

Pedro Neto (Chelsea)

Over 0.5

-103

Under 0.5

-164

Jamie Bynoe-Gittens (Chelsea)

Over 0.5

+104

Under 0.5

-164

Facundo Buonanotte (Chelsea)

Over 0.5

+115

Under 0.5

-182

Bryan Mbeumo (United)

Over 1.5

+140

Under 1.5

-227

Enzo Fernández (Chelsea)

Over 0.5

+148

Under 0.5

-263

Tyrique George (Chelsea)

Over 0.5

+165

Under 0.5

-278

Carlos Casemiro (United)

Over 0.5

+175

Under 0.5

-294

Mason Mount (United)

Over 0.5

+190

Under 0.5

-333

Andrey Nascimento dos Santos (Chelsea)

Over 0.5

+195

Under 0.5

-333

Kobbie Mainoo (United)

Over 0.5

+235

Under 0.5

-435

Patrick Dorgu (United)

Over 0.5

+260

Under 0.5

-500

Marc Cucurella (Chelsea)

Over 0.5

+300

Under 0.5

-769

Estêvão Willian Gonçalves (Chelsea)

Over 3.5

+400

Under 3.5

-

Bryan Mbeumo (United)

Over 3.5

+135

Under 3.5

-

Alejandro Garnacho (Chelsea)

Over 2.5

+112

Under 2.5

-

Benjamin Sesko (United)

Over 2.5

-116

Under 2.5

-

Cole Palmer (Chelsea)

Over 2.5

-130

Under 2.5

-

Bruno Fernandes (United)

Over 2.5

-111

Under 2.5

-

Matheus Cunha (United)

Over 2.5

-130

Under 2.5

-

João Pedro (Chelsea)

Over 2.5

-111

Under 2.5

-

Joshua Zirkzee (United)

Over 1.5

-125

Under 1.5

-

Pedro Neto (Chelsea)

Over 1.5

-120

Under 1.5

-

Amad Diallo (United)

Over 1.5

-130

Under 1.5

-

Facundo Buonanotte (Chelsea)

Over 1.5

-100

Under 1.5

-

Jamie Bynoe-Gittens (Chelsea)

Over 1.5

-118

Under 1.5

-

Enzo Fernández (Chelsea)

Over 1.5

+132

Under 1.5

-

Carlos Casemiro (United)

Over 0.5

-250

Under 0.5

-

Patrick Dorgu (United)

Over 0.5

-147

Under 0.5

-

Marc Cucurella (Chelsea)

Over 0.5

-130

Under 0.5

-

United have managed five victories, three losses and two draws in the last 10 home matches, recording an average of 1.60 goals per game and conceding 1.10.

Chelsea haven’t been beaten in three straight games away from home. The West London side have five defeats, three victories and two draws in the last 10 away matches, netting an average of 1.20 goals per game and conceding 1.50.

The last meeting at Old Trafford saw United and Chelsea draw 1-1. The past 7 H2H meetings at Old Trafford have included four draws and three United wins.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Manchester United Home Stats		5-2-3	2.70	1.60	1.10	4	6	5	5
Chelsea Away Stats		3-2-5	2.70	1.20	1.50	6	4	5	5

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

Manchester United vs Chelsea Lineups & Team News

Before placing any bets on United vs Chelsea, check the team news first. We’ll bring you both the expected and confirmed lineups for the Premier League, along with current injury news.

Manchester United Team Page Chelsea Team Page

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