Monterrey vs Santos Laguna Prediction, Betting Tips, Lineups & Odds | 27 Sep 2025

Liga MX Betting Preview: Monterrey vs Santos Laguna

Monterrey host Santos Laguna in this Liga MX fixture at Estadio BBVA, with kick-off set for 21:00 on Saturday 27 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

BTTS Yes is Our Best Bet

The best betting angle could be backing Monterrey and Santos Laguna to both score at least once, especially as odds of -120 are available when it comes to the BTTS Yes selection.

Fancy our BTTS Yes tip? Unlock the latest BetMGM promo code and read our detailed review before placing your bet.

7 Wins in Previous 10 H2H Games for Rayados

Monterrey were defeated in their last game. On the road, they suffered a 6-2 loss against Deportivo Toluca at Estadio Nemesio Diez. Monterrey enjoyed 53% possession and four shots on target, with German Berterame and Oliver Torres scoring one goal each.

Santos Laguna won their previous game, beating Club Tijuana at home. It was a 1-0 win at Estadio Nuevo Corona. Francisco Rodriguez's men had 46% possession and totalled five shots on goal, with Cristian Dajome scoring the winner in the final few minutes.

Head-to-Head Statistics

Monterrey have won five on the bounce against Santos. In their last encounter, Monterrey came out with a 4-2 home victory at Estadio BBVA. The past 10 H2H meetings have included seven victories for Monterrey, two wins for Santos and a single draw.

Liga MX		G	W	D	L	GF	GA	GD	GD	P
3	Monterrey	10	7	1	2	22	17	5	22:17	22
13	Santos Laguna	10	3	1	6	13	17	-4	13:17	10

View Full Table

7 wins, 2 losses and 1 draw, averaging 2.2 goals from 5.0 shots on goal and 9.6 attempts. Rayados have had 57.4% possession and 4.7 corners per game. On average, they have conceded 1.7 goals from 4.0 shots on goal and 7.4 attempts, while the opposition have been awarded 5.1 corners.

German Berterame and Sergio Canales are the leading goalscorers with 6, while Lucas Ocampos has 4. Leading assistor is Lucas Ocampos with 4.

Santos have 3 victories, 6 defeats and 1 draw, averaging 3.6 shots on goal, 6.6 attempts and 1.3 goals. The Comarca Lagunera outfit average 44.9% possession, 4.3 corners taken and 6.2 corners against them, while 1.7 goals have been conceded from 12.9 attempts and 5.6 shots on goal.

Cristian Dajome has scored 4, followed by Jesus Ocejo, Bruno Barticciotto and Ramiro Sordo with 2 goals apiece. Jose Abella has managed to clock up 2 assists in the last 10 games.

Predicted & Confirmed Lineups

Monterrey predicted lineup (3-4-2-1): Santiago Mele (GK), Fidel Ambríz, Sergio Ramos, Stefan Medina, Érick Aguirre, Jorge Rodriguez, Oliver Torres, Luis Ricardo Reyes, Sergio Canales, Jesus Manuel Corona, Germán Berterame.

Santos Laguna predicted lineup (4-2-3-1): Carlos Acevedo Lopez (GK), José Javier Abella, Kevin Balanta, Jonathan Pérez, Bruno Amione, Javier Güemez, Kevin Palacios, Ramiro Sordo, Salvador Mariscal, Jordan Carrillo, Jesús Ocejo.

Monterrey vs Santos Laguna Prediction & Betting Tips

Your complete Monterrey vs Santos Laguna betting guide is here, including our go-to match prediction, scoreline call, corners betting pick, standout prop selections and a customized bet builder.

Match Prediction

It’s likely that we’ll see the two teams finding the net and that leads us to bet BTTS Yes for this Liga MX showdown. This betting selection is priced at -120 and can be backed with confidence.

Injuries and suspensions are taken into account by the Liga MX experts at Sportsgambler.com. Our football betting tips are also shaped by the latest form, with the stats playing a big part before predictions are made.

Key Monterrey vs Santos Laguna league stats:

• BTTS Yes has been covered in 4 of the last 5 Monterrey games at home.
• BTTS Yes has been covered in 7 of the last 10 Monterrey games at home.
• BTTS Yes has been covered in 2 straight Monterrey games.
• BTTS Yes has been covered in 3 straight Santos games on the road.
• BTTS Yes has been covered in 7 of the last 10 Santos games on the road.
• BTTS Yes has been covered in 10 of the last 17 Santos games on the road.

BTTS Yes Probability

If you go by the best football betting sites, our pick has a 54.6% chance of delivering a return. After careful examination, our tipsters calculate this probability to be closer to 60%. It is therefore regarded as a value bet.

If you want to take a slightly different betting approach, why not consider the Over 2.5 Goals option where you need three or more to be scored.

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Our Match Prediction

Both Teams To Score - Yes @ -120 Watch Live Bet Now

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Correct Score Prediction

Monterrey 1 - 1 Santos

There are odds of +850 that the two teams play out a 1-1 scoreline. The correct score option is popular due to the potential return that can be achieved.

Player Prop Picks

Top Pick: Sergio Ramos Under 0.5 Shots On Target -161

Sergio Ramos (Monterrey) is available at -161 to fail to have a shot on goal. It’s hard to turn down such attractive odds for this player when it comes to Shots on Target.

Latest Sergio Ramos Player Prop Odds

Goalscorer

Anytime

+240

First

+800

Shots On Target

Over 0.5

+102

Under 0.5

-161

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Sergio Canales to Score +135

Sergio Canales (Monterrey) has scored in his past two Liga MX home games. When it comes to him scoring, we think that the +135 available is attractive when betting on the Anytime Goalscorer market.

Latest Sergio Canales Player Prop Odds

Goalscorer

Anytime

+135

First

+420

Shots On Target

Over 0.5

-263

Under 0.5

+160

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Corners Prediction

Monterrey Under 6.5 Corners -118

We’ve seen an average of 3.60 corners for Monterrey in their past 5 matches, while the previous five Santos games have involved them conceding under 6.5 corners. On this evidence, we can take odds of -118 that this Monterrey Team Corners wager falls short of the line.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Monterrey

Total

9.80 4.70 5.10

Home

8.20 3.70 4.50

Away

9.20 4.80 4.40

Santos

Total

10.50 4.30 6.20

Home

9.60 4.60 5.00

Away

11.50 4.60 6.90

Latest Corner Odds

Total Corners

Over 10.5

-119

Under 10.5

-125

Monterrey Corners

Over 6.5

-110

Under 6.5

-125

Santos Corners

Over 3.5

-100

Under 3.5

-138

Most Corners

1

-400

X

+750

2

+360

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Monterrey vs Santos Laguna Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Rayados Victory on the Cards According to Betting Sites

Monterrey are convincing -357 favourites to land the spoils in this Liga MX encounter, which means a 78% likelihood of securing a victory according to the current betting odds. If you’re searching for a different slant, outsiders Santos Laguna are available at +800.

There is -122 available if you want to back Monterrey -1.5 on the Asian Handicap. This might appeal to bettors who think that they can overcome Santos by a two-goal margin or bigger.

The odds suggest that Over 2.5 Goals is a strong probability in this exciting contest. If you’re wagering on Both Teams to Score, you can bet Yes at -120 and No at -118.

If you visit one of the recommended betting sites, it’s fantastic to access hundreds of markets for whichever Liga MX game appeals. Scan through the choices and pick your football wager.

Full-Time Result

1

-357

X

+460

2

+800

Half-Time Result

1

-152

X

+175

2

+575

Double Chance

1X

-3333

12

-1000

X2

+215

Draw No Bet

1

-1111

2

+525

Asian Handicap

1 Hcp -1.5

-122

2 Hcp +1.5

-102

Total Goals

Under 2.5

+155

Over 2.5

-213

Both Teams to Score

Yes

-120

No

-118

Germán Berterame Favourite to Be First Goalscorer

Germán Berterame is favourite to be First Goalscorer at +290 and if you’re keen to back him to simply find the net, then the price is -118.

Germán Berterame (Monterrey)

First

-118

Anytime

+290

Sergio Canales (Monterrey)

First

+135

Anytime

+420

Lucas Ocampos (Monterrey)

First

+180

Anytime

+575

Sergio Ramos (Monterrey)

First

+240

Anytime

+800

Jesús Corona (Monterrey)

First

+250

Anytime

+750

Bruno Barticciotto (Santos)

First

+320

Anytime

+950

Érick Aguirre (Monterrey)

First

+370

Anytime

+1100

Ramiro Sordo (Santos)

First

+400

Anytime

+1150

Fidel Ambriz (Monterrey)

First

+440

Anytime

+1300

Oliver Torres (Monterrey)

First

+450

Anytime

+1300

Jordan Carrillo (Santos)

First

+550

Anytime

+1600

Fran Villalba (Santos)

First

+600

Anytime

+1800

Hector Moreno (Monterrey)

First

+650

Anytime

+1900

Ronaldo Prieto (Santos)

First

+650

Anytime

+1900

Ricardo Chavez (Monterrey)

First

+650

Anytime

+2000

Diego Javier Medina Vázquez (Santos)

First

+700

Anytime

+1900

Cristian Dájome (Santos)

First

+700

Anytime

+1900

Luis Reyes (Monterrey)

First

+700

Anytime

+2000

Víctor Andrés Guzmán (Monterrey)

First

+750

Anytime

+2200

Salvador Mariscal Murra (Santos)

First

+800

Anytime

+2200

Gerardo Arteaga (Monterrey)

First

+850

Anytime

+2200

Sergio Canales (Monterrey)

Over 0.5

-263

Under 0.5

+160

Lucas Ocampos (Monterrey)

Over 0.5

-175

Under 0.5

-100

Germán Berterame (Monterrey)

Over 1.5

-122

Under 1.5

-143

Bruno Barticciotto (Santos)

Over 0.5

-112

Under 0.5

-154

Jesús Corona (Monterrey)

Over 0.5

-100

Under 0.5

-159

Sergio Ramos (Monterrey)

Over 0.5

+102

Under 0.5

-161

Ramiro Sordo (Santos)

Over 0.5

+123

Under 0.5

-208

Jordan Carrillo (Santos)

Over 0.5

+165

Under 0.5

-270

Érick Aguirre (Monterrey)

Over 0.5

+170

Under 0.5

-294

Fran Villalba (Santos)

Over 0.5

+200

Under 0.5

-357

Oliver Torres (Monterrey)

Over 0.5

+205

Under 0.5

-385

Fidel Ambriz (Monterrey)

Over 0.5

+210

Under 0.5

-370

Diego Javier Medina Vázquez (Santos)

Over 0.5

+240

Under 0.5

-417

Ronaldo Prieto (Santos)

Over 0.5

+250

Under 0.5

-455

Cristian Dájome (Santos)

Over 0.5

+250

Under 0.5

-500

Salvador Mariscal Murra (Santos)

Over 0.5

+275

Under 0.5

-556

Ricardo Chavez (Monterrey)

Over 0.5

+310

Under 0.5

-667

Monterrey Tough to Defeat in Recent Home Games

Monterrey have not tasted defeat at Estadio BBVA in six straight matches. They have collected seven victories, two losses and one draw in the last 10 home games, recording an average of 2.20 goals per match and conceding 1.20.

Santos Laguna haven’t tasted victory in the previous ten away matches. Francisco Rodriguez's team have clocked up eight losses and two draws in the past 10 away games, recording an average of 1.10 goals per match and conceding 2.30.

The last Estadio BBVA meeting saw Monterrey beat Santos 4-2. We’ve seen six Monterrey wins, one Santos victory and two draws in the past 9 H2H meetings at Estadio BBVA.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Monterrey Home Stats		7-1-2	3.40	2.20	1.20	8	2	7	3
Santos Laguna Away Stats		0-2-8	3.40	1.10	2.30	7	3	7	3

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

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Monterrey vs Santos Laguna Lineups & Team News

Double-check the Rayados vs Santos team news before placing your bets. Stay in the know with our predicted and confirmed Liga MX lineups and the latest on injuries.

Monterrey Team Page Santos Laguna Team Page