Puebla vs Santos Laguna Prediction, Betting Tips, Lineups & Odds | 25 Jul 2025

Liga MX Betting Preview: Puebla vs Santos Laguna

Puebla host Santos Laguna in this Liga MX match at Estadio Cuahutehmoc, with kick-off set for 21:00 on Friday 25 July. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

Puebla Stand Out on the Betting Coupon

Puebla have the capability of securing a victory when they clash with Santos Laguna. For this reason, we are going to take the Full-Time Result odds of +105 with a large degree of confidence.

Backing Puebla to come through? Be sure to grab the BetMGM promo code and give our review a read before betting.

2-0 Win for Puebla in Last Head-to-Head

Club Puebla have suffered defeat in their last two Liga MX games. Most recently, a 2-1 scoreline occurred on the road at Estadio El Encanto against Mazatlán. Pablo Guede's team boasted 57% possession and had five shots on target, while Emiliano Gomez bagged the goal.

Santos Laguna were beaten in their previous game, losing 4-2 at home to Deportivo Toluca at Estadio Nuevo Corona. Los Guerreros were restricted to 45% possession and had five shots on goal, with Ramiro Sordo and Jesus Ocejo finding the net.

Head-to-Head Statistics

Puebla have won the last two head-to-heads against Santos. On their travels, a 2-0 win was secured at Estadio Nuevo Corona and that was preceded by a 1-0 home success at Estadio Cuahutehmoc. The previous 10 H2H games have resulted in four wins apiece and two draws.

Liga MX		G	W	D	L	GF	GA	GD	GD	P
11	Santos Laguna	8	2	1	5	11	13	-2	11:13	7
18	Puebla	8	1	1	6	7	21	-14	7:21	4

View Full Table

9 losses and 1 draw, averaging 0.4 goals from 4.1 shots on goal and 9.5 attempts. Club Puebla have had 46.3% possession and 4.6 corners per game. On average, they have conceded 1.8 goals from 4.6 shots on goal and 10.4 attempts, while the opposition have been awarded 4.4 corners.

The four top scorers are Emiliano Gomez, Esteban Lozano, Edgar Guerra and Facundo Waller, with these players all scoring 1 goals. Jose Pachuca and Edgar Guerra are the top assists makers with 1.

Santos have 2 victories and 8 defeats, averaging 3.4 shots on goal, 9.2 attempts and 1.3 goals. The Comarca Lagunera side average 48.1% possession, 4.1 corners awarded and 4.7 corners against, while 2.5 goals have been conceded from 12.8 attempts and 5.7 shots on goal.

Ramiro Sordo is top of the team’s scoring charts with 4 goals, Bruno Barticciotto has 3 and Aldo Lopez is on 2. Look no further than Fran Villalba for the top assist maker (3) in the last 10 games.

Confirmed Lineups

Puebla confirmed lineup (4-3-3): Jesus Ivan Rodriguez (GK), Nicolas Diaz, Franco Moyano, Luis Gabriel Rey, Juan Fedorco, Ariel Gamarra, Alejandro Organista, Miguel Ramirez, Esteban Lozano, Edgar Guerra, Owen Gonzalez.

Santos Laguna confirmed lineup (5-3-2): Carlos Acevedo (GK), Emmanuel Echeverria, Bruno Amione, Kevin Balanta, Jose Abella, Oscar Ortega, Aldo Lopez, Fran Villalba, Ramiro Sordo, Anthony Lozano, Javier Guemez.

Puebla vs Santos Laguna Prediction & Betting Tips

Unlock a complete betting breakdown for Puebla vs Santos Laguna, featuring our expert match prediction, expected final score, corners insight and a ready-to-play bet builder.

Match Prediction

If you agree with our verdict that Puebla can claim a Liga MX victory, then there’s the chance to get betting odds of +105 that this happens. We think that this price sticks out.

Our football betting tips are provided off the back of having access to the very latest team news. We also think it’s vital to study the form guide and delve into the most pertinent Liga MX stats before coming up with a verdict.

Key Puebla vs Santos Laguna league stats:

• Santos have lost their last 4 games on the road.
• Santos have lost 9 of their last 10 games on the road.
• Santos have lost 15 of their last 17 games on the road.
• Puebla have won the last 2 games between these teams.

Puebla to Win Probability

The odds at the best football bookies suggest our pick has a 48.8% chance of winning. Our experts think there’s a stronger chance of success and calculate the probability to be 55-60%. This is why we can recommend this wager.

We’d recommend taking a look at the Asian Handicap, Double Result and Result & Both Teams to Score markets if you’re interested in siding with Puebla but want bigger odds.

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Our Match Prediction

Puebla To Win @ +105 Bet Now

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Correct Score Prediction

Puebla 2 - 1 Santos

Puebla can be backed to win 2-1 when it comes to the correct score. We’ll go for the +750 that this happens and hopefully we’ll get a good run for our money.

Corners Prediction

Santos Under 4.5 Corners -138

Santos have had under 4.5 corners in four consecutive away games, with Puebla conceding less than 4.5 corners in their past five matches. The Santos Team Corners line looks to be too big given the stats and -138 is available to wager.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Puebla

Total

9.00 4.60 4.40

Home

9.30 4.10 5.20

Away

8.80 3.80 5.00

Santos

Total

8.80 4.10 4.70

Home

10.10 5.20 4.90

Away

10.80 4.30 6.50

Latest Corner Odds

Total Corners

Over 9.5

-122

Under 9.5

-122

Puebla Corners

Over 5.5

+110

Under 5.5

-150

Santos Corners

Over 3.5

-163

Under 3.5

+120

Most Corners

1

-159

X

+650

2

+175

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Puebla vs Santos Laguna Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Bookies Make Puebla Favourites to Win

Club Puebla are the -110 favourites on the 1x2 betting. That implies a 52% chance of triumphing in this Liga MX encounter according to the latest odds. For those wanting to oppose the market leader, you can get +245 about Santos Laguna.

You can choose Puebla -0.5 or Santos +0.5 at respective Asian Handicap odds of -116 and -122. The former is the same as betting the favourites to win, with the latter giving you a return if it’s a draw.

For those expecting a high-scoring contest, Over 2.5 Goals is the shortest price. BTTS Yes is available at -147 for anyone expecting Both Teams to Score.

You’ll love the hundreds of markets if you want to bet on the Liga MX coupon and we advise heading to the top sports betting sites to get the football wager that you think is value.

Full-Time Result

1

-110

X

+265

2

+245

Half-Time Result

1

+148

X

+120

2

+280

Double Chance

1X

-417

12

-455

X2

-130

Draw No Bet

1

-233

2

+155

Asian Handicap

1 Hcp -0.5

-116

2 Hcp +0.5

-122

Total Goals

Under 2.5

-108

Over 2.5

-133

Both Teams to Score

Yes

-147

No

+102

Puebla Searching For Improved Results at Home

Puebla haven’t tasted victory in five consecutive matches at Estadio Cuahutehmoc. Pablo Guede's team have recorded seven defeats, two victories and one draw in the previous 10 home matches, netting an average of 0.80 goals per game and conceding 1.50.

Santos Laguna are winless over their previous ten games on their travels. Los Guerreros have nine defeats and one draw in the last 10 away games, scoring an average of 0.90 goals per match and conceding 2.20.

Puebla enjoyed a 1-0 winning scoreline when last meeting Santos at Estadio Cuahutehmoc. The past 8 H2H meetings at Estadio Cuahutehmoc have featured three triumphs for Puebla, two for Santos and three draws.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Puebla Home Stats		2-1-7	2.30	0.80	1.50	5	5	4	6
Santos Laguna Away Stats		0-1-9	3.10	0.90	2.20	6	4	6	4

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

Puebla vs Santos Laguna Lineups & Team News

Before making your bets, take a look at the Puebla vs Santos team news. We’ll deliver the predicted and confirmed Liga MX lineups as well as the most recent injury news.

Puebla Team Page Santos Laguna Team Page