Pumas vs San Luis Prediction, Betting Tips, Lineups & Odds | 22 Oct 2025

Liga MX Betting Preview: Pumas vs San Luis

Pumas host San Luis in this Liga MX encounter at Olimpico Universitario, with kick-off set for 23:05 on Wednesday 22 October. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

Back a Close Game

San Luis stand out as a value wager at -118 with a +0.75 headstart. We anticipate this Asian Handicap could see them prosper against Pumas, with our stake equally divided between +0.5 and +1.0.

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Pumas Beat San Luis in their Previous Meeting

Pumas UNAM drew on the road in their last game. A 1-1 scoreline was played out against Monterrey at Estadio BBVA. The Mexico City club had just 37% possession and recorded two shots on target, while Alan Medina was the goalscorer.

Atlético San Luis have suffered successive Liga MX road losses. Their most recent league game was a 2-0 home victory at Estadio Alfonso Lastras where they beat Atlas. Guillermo Abascal's men were 50% in the possession stakes and recorded three shots on goal, with Joao Pedro and Oscar Macias finding the net.

Head-to-Head Statistics

Pumas have claimed victories in the last two encounters against San Luis. The most recent was a 3-2 away win at Estadio Alfonso Lastras after a 3-0 home victory at Olimpico Universitario. There have been six Pumas triumphs and four San Luis wins in the previous 10 games involving these sides.

Liga MX		G	W	D	L	GF	GA	GD	GD	P
10	Pumas	13	3	5	5	16	20	-4	16:20	14
11	San Luis	13	4	1	8	19	20	-1	19:20	13

View Full Table

Pumas UNAM have 2 wins, 3 losses and 5 draws, averaging 1.2 goals from 3.0 shots on goal and 7.0 attempts. Efrain Juarez's side have averaged 50.1% possession and 4.7 corners per game, with their opponents scoring 1.4 goals from 4.0 shots on goal, 8.3 attempts and 4.1 corners.

Guillermo Martinez is the top scorer with 3 goals, while Alan Medina, Jorge Ruvalcaba and Jose Macias each have 2. Jorge Ruvalcaba, Jose Macias and Adalberto Carrasquilla have racked up the most assists with 2 each.

San Luis have 3 victories, 6 defeats and 1 draw, with an average of 1.5 goals from 6.4 attempts and 3.3 shots on goal. There’s been an average of 49.9% possession, 4.2 corners awarded and 4.3 corners against them, while they’ve conceded 1.5 goals from 8.5 attempts and 4.1 shots on goal.

Joao Pedro is the leading scorer with 7 goals, followed by Benjamin Galdames on 2, with Oscar Macias and two others bagging 1. Juan Sanabria and Miguel Garcia have had 2 assists in the previous 10 games.

Predicted & Confirmed Lineups

Pumas predicted lineup (4-2-3-1): Keylor Navas (GK), Pablo Bennevendo, Ángel Azuaje, Nathan Silva, Alvaro Angulo, José Caicedo, Pedro Vite, Alan Medina, Adalberto Carrasquilla, Jorge Ruvalcaba, José Juan Macías.

San Luis predicted lineup (4-2-3-1): Andrés Sánchez (GK), Román Torres, Robson Bambu, Eduardo Águila, Juan Manuel Sanabria, Sébastien Salles Lamonge, Rodrigo Dourado, Benjamín Galdames, Sebastián Pérez Bouquet, Miguel García, João Pedro Galvão.

Pumas vs San Luis Prediction & Betting Tips

We’ve got your Pumas vs San Luis bets covered, including our expert match prediction, correct score tip, corners outlook, must-see player props and a tailored bet builder built for value.

Match Prediction

San Luis should be highly competitive in this Liga MX match. On this basis, we’ll take them at -118 on the Asian Handicap +0.75 feeling optimistic that the underdogs will land a payout.

The football betting tips are only provided once we have a handle on the team news and the latest form guide. We are also on point when it comes to the most valuable Liga MX stats.

Key Pumas vs San Luis league stats:

• The -0.75 line hasn’t been covered by Pumas in 5 consecutive games.
• The -0.75 line hasn’t been covered by Pumas in 8 of their last 10 games.
• The -0.75 line hasn’t been covered by Pumas in 15 of their last 20 games.

San Luis +0.75 Probability

If you go by the top bookies, there’s a 54.1% likelihood of our pick winning. After careful examination, our tipsters calculate this probability to be closer to 60%. It’s the reason why we are recommending this wager.

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Our Match Prediction

San Luis Asian Hcp +0.75 @ -118 Watch Live Bet Now

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Correct Score Prediction

Pumas 1 - 1 San Luis

Our prediction is a 1-1 draw which is available at odds of +600. Correct score betting allows us to bet at bigger odds and it’s also a fun type of wager.

Player Prop Picks

Top Pick: Jorge Ruvalcaba Over 0.5 Shots On Target -112

Jorge Ruvalcaba (Pumas) can be backed to record a minimum of one shot on goal at -112. We’ll take a chance with this Shots on Target pick as the betting odds look pretty attractive.

Latest Jorge Ruvalcaba Player Prop Odds

Goalscorer

Anytime

+270

First

+750

Shots On Target

Over 0.5

-112

Under 0.5

-139

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Benjamín Galdames to Score +575

Benjamín Galdames (San Luis) has racked up two goals in his past seven Liga MX games on the road. It’s worth a play on the +575 that he is Anytime Goalscorer as there’s lots of value for these betting odds.

Latest Benjamín Galdames Player Prop Odds

Goalscorer

Anytime

+575

First

+1500

Shots On Target

Over 0.5

+205

Under 0.5

-417

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Corners Prediction

Under 10.5 Corners -149

There has been under 10.5 corners in eight consecutive San Luis matches. On this basis, we can take odds of -149 that this Total Corners bet falls short of the line.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Pumas

Total

8.80 4.70 4.10

Home

9.40 5.70 3.70

Away

7.70 2.80 4.90

San Luis

Total

8.50 4.20 4.30

Home

9.30 4.70 4.60

Away

11.30 5.60 5.70

Latest Corner Odds

Total Corners

Over 10.5

-100

Under 10.5

-149

Pumas Corners

Over 5.5

-110

Under 5.5

-125

San Luis Corners

Over 3.5

-138

Under 3.5

-100

Most Corners

1

-200

X

+650

2

+200

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Pumas vs San Luis Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Pumas Made Favourites by the Bookies

Pumas UNAM are the skinniest price to succeed in this Liga MX clash, with the favourites afforded a 58% probability based on their -137 betting odds with the bookies. Atlético San Luis are regarded as the least likely winner at +320.

Pumas and San Luis can be backed at +125 and +320 respectively on the Half-Time Result market. This is an ideal route for bettors who want a quick settlement and the draw is +135.

The Over 2.5 option is currently favourite on the Total Goals betting market. Both Teams to Score is one of the top markets and the BTTS Yes option can be wagered at -152.

The good news is that you can access hundreds of markets for any Liga MX game. The best football betting sites have a massive range of pre-match and In-Play betting options.

Full-Time Result

1

-137

X

+290

2

+320

Half-Time Result

1

+125

X

+135

2

+320

Double Chance

1X

-556

12

-500

X2

-106

Draw No Bet

1

-303

2

+205

Asian Handicap

1 Hcp -0.75

-105

2 Hcp +0.75

-118

Total Goals

Under 2.5

+110

Over 2.5

-149

Both Teams to Score

Yes

-152

No

+106

Guillermo Martinez Heads First Goalscorer Market

Guillermo Martinez is the market leader at +340 to be First Goalscorer but if you think he will score the last goal, then a similar price can be found.

Guillermo Martinez (Pumas)

First

+115

Anytime

+340

João Galvão (San Luis)

First

+175

Anytime

+480

Jorge Ruvalcaba (Pumas)

First

+270

Anytime

+750

Pedro Vite (Pumas)

First

+280

Anytime

+800

Aaron Ramsey (Pumas)

First

+350

Anytime

+950

Adalberto Carrasquilla (Pumas)

First

+480

Anytime

+1200

Juan Manuel Sanabria (San Luis)

First

+480

Anytime

+1300

Álvaro Angulo (Pumas)

First

+550

Anytime

+1600

Benjamín Galdames (San Luis)

First

+575

Anytime

+1500

Santiago Trigos (Pumas)

First

+650

Anytime

+1900

Rubén Duarte (Pumas)

First

+750

Anytime

+2000

Nathanael Ananias da Silva (Pumas)

First

+750

Anytime

+2200

Pablo Bennevendo (Pumas)

First

+750

Anytime

+2200

Jose Luis Caicedo (Pumas)

First

+850

Anytime

+2200

João Galvão (San Luis)

Over 0.5

-263

Under 0.5

+143

Jorge Ruvalcaba (Pumas)

Over 0.5

-112

Under 0.5

-139

Pedro Vite (Pumas)

Over 0.5

+110

Under 0.5

-175

Aaron Ramsey (Pumas)

Over 0.5

+135

Under 0.5

-222

Juan Manuel Sanabria (San Luis)

Over 0.5

+170

Under 0.5

-333

Adalberto Carrasquilla (Pumas)

Over 0.5

+200

Under 0.5

-345

Benjamín Galdames (San Luis)

Over 0.5

+205

Under 0.5

-417

Álvaro Angulo (Pumas)

Over 0.5

+230

Under 0.5

-500

Santiago Trigos (Pumas)

Over 0.5

+280

Under 0.5

-526

Rubén Duarte (Pumas)

Over 0.5

+340

Under 0.5

-1111

Nathanael Ananias da Silva (Pumas)

Over 0.5

+350

Under 0.5

-1111

Pablo Bennevendo (Pumas)

Over 0.5

+350

Under 0.5

-1111

Jose Luis Caicedo (Pumas)

Over 0.5

+350

Under 0.5

-769

Pumas Have Won Past Three H2H Olimpico Universitario Meetings

Pumas have managed five draws, three losses and two victories in the last 10 home matches, recording an average of 1.10 goals per game and conceding 1.20.

San Luis have finished with six defeats and four wins in the past 10 away games, netting an average of 1.80 goals per match and conceding 1.90.

Pumas enjoyed a 3-0 winning scoreline when last meeting San Luis at Olimpico Universitario. Pumas have landed victory in five of the previous 6 H2H games at Olimpico Universitario, with San Luis winning once.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Pumas Home Stats		2-5-3	2.30	1.10	1.20	4	6	6	4
San Luis Away Stats		4-0-6	3.70	1.80	1.90	8	2	7	3

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

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Pumas vs San Luis Lineups & Team News

Don’t bet on Pumas vs San Luis without reviewing the latest team news. Stay in the know with our predicted and confirmed Liga MX lineups and the latest on injuries.

Pumas Team Page San Luis Team Page