San Luis vs León Prediction, Betting Tips, Lineups & Odds | 21 Mar 2026

Liga MX Betting Preview: San Luis vs León

San Luis square off against León at Estadio Alfonso Lastras, with kick-off set for 21:00 on Saturday 21 March.

San Luis look like a spot of value at -100 when it comes to the Full-Time Result market. The home team should be able to deliver a victory against León based on the information available.

Atlético San Luis drew their last game 1-1 at home, with the action taking place at Estadio Alfonso Lastras against Pachuca. Guillermo Abascal's team had most of the ball enjoying 55% possession and two shots on target, with Joao Pedro bagging the goal.

Club León have been defeated in their previous four road games. They recently suffered a 5-0 loss against Guadalajara at Estadio Akron. La Fiera finished with just 24% possession and one shot on goal.

Head-to-Head Statistics

The last encounter between San Luis and León saw the former win away from home. It was a 1-0 scoreline at Estadio Nou Camp. There has been five wins apiece in the past 10 H2H meetings.

Liga MX		G	W	D	L	GF	GA	GD	GD	P
12	San Luis	11	3	2	6	17	19	-2	17:19	11
16	León	11	3	1	7	11	23	-12	11:23	10

View Full Table

3 wins, 5 losses and 2 draws, averaging 1.6 goals from 7.5 attempts and 3.9 shots on goal. San Luis have had 50.7% possession and 3.5 corners per match. On average, the opposition have scored 1.7 goals from 11.1 attempts and 5.4 shots on goal, while earning 3.4 corners.

Top goalscorer Joao Pedro has found the net 9 times, with Sebastien Lamonge, Eduardo Aguila, Jesus Medina and Miguel Garcia scoring 1 each. The leading assistors have been Jesus Medina and Santiago Munoz with 2.

Club León have 2 victories, 7 defeats and 1 draw, with an average of 0.9 goals from 4.0 shots on goal and 9.1 attempts. Ignacio Ambriz's side have averaged 50.5% possession, 4.7 corners awarded and 5.4 corners against, while they’ve conceded 2.2 goals from 6.2 shots on goal and 11.8 attempts.

Diber Cambindo has scored 5 goals, followed by Ismael Diaz, Juan Dominguez, Daniel Arcila and Rogelio Funes Mori on 1. Jordi Cortizo, Juan Dominguez and Ismael Diaz have been the top assists providers with 1 in the previous 10 games.

Predicted & Confirmed Lineups

San Luis predicted lineup (5-4-1): Andrés Sánchez (GK), Román Torres, Benjamín Galindo, Juanpe, Eduardo Águila, Lucas Esteves, Sebastián Pérez Bouquet, Óscar Macías, Jesús Medina, Sébastien Salles Lamonge, João Pedro Galvão.

León predicted lineup (4-2-3-1): Jordan Garcia (GK), Ivan Moreno, Sebastian Vegas, Jaine Stiven Barreiro, Salvador Reyes, José Ivan Rodríguez, Juan Pablo Domínguez, Rodrigo Echeverria, Ismael Díaz, Nicolas Javier Vallejo, Diber Cambindo.

San Luis vs León Prediction & Betting Tips

We dive into the top San Luis vs León betting angles, including our main match prediction, correct score play, corners market tip, standout player prop picks and a bet builder tailored for value.

Match Prediction

We believe there’s a strong case for siding with San Luis. That’s because we think they could prove too strong in this Liga MX encounter and odds of -100 are highly attractive.

The latest Liga MX team news and current form are always useful information when it comes to providing football betting tips. It’s also important to pay attention to the available stats so that we make the best picks.

Key San Luis vs León league stats:

• León have lost their last 4 games on the road.
• León have lost 9 of their last 10 games on the road.
• León have lost 15 of their last 19 games on the road.

The latest betting odds imply that our pick has a 50% prospect of winning. After careful examination, our tipsters calculate this probability to be somewhere between 55-60%. It’s why we think it’s worth placing this bet.

If you’re looking to squeeze more juice from the odds, consider San Luis on the Asian Handicap. Those expecting our winner to exceed expectations can bet them to cover the line.

Don’t place another bet without seeing the best betting offers available—free bets and welcome promos included.

Our Match Prediction

San Luis To Win @ -100 Watch Live Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Mar 20, 03:27). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

San Luis 1 - 0 León

One bet that has caught our eye is San Luis to claim a 1-0 correct score win. This selection is available at +650 meaning that a winning selection will yield a nice return.

Player Prop Picks

Top Pick: Jesús Medina To Score +280

Jesús Medina (San Luis) can be backed to be on the scoresheet at +280. The Anytime Goalscorer odds look really appealing considering all angles and we’ll take a chance on him.

Latest Jesús Medina Player Prop Odds

Goalscorer

Anytime

+280

First

+750

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Corners Prediction

Under 9.5 Corners -132

It has been under 9.5 corners in six straight San Luis home matches. We’re willing to wager the -132 when it comes to the sides being short of the Total Corners line which looks appealing.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

San Luis

Total

6.90 3.50 3.40

Home

8.20 4.70 3.50

Away

6.70 3.30 3.40

León

Total

10.10 4.70 5.40

Home

9.90 5.10 4.80

Away

10.60 5.00 5.60

Latest Corner Odds

Total Corners

Over 9.5

-114

Under 9.5

-132

San Luis Corners

Over 5.5

-100

Under 5.5

-159

León Corners

Over 3.5

-156

Under 3.5

-100

Most Corners

1

-164

X

+650

2

+170

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

San Luis vs León Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Atlético San Luis are forecasted to be the most likely winner in this Liga MX encounter. The -100 for them coming out on top suggests a 50% probability based on their latest betting odds. For those wanting to back Club León, you will find +235 about this outsider.

Asian Handicap betting is popular and you can wager San Luis -0.5 at -100 should you want to go for the favourites, with León +0.5 available at -130 and you will also win with the latter if it’s a draw.

Over 2.5 Goals is available at shorter odds than Under 2.5 Goals as things stand. If you’re anticipating that both teams will score, the BTTS Yes option can be wagered at -189.

The good news is that you can access hundreds of markets for any Liga MX match. All the leading football betting sites have a massive range of pre-match and In-Play betting options.

Full-Time Result

1

-100

X

+260

2

+235

Half-Time Result

1

+150

X

+130

2

+265

Double Chance

1X

-357

12

-400

X2

-141

Draw No Bet

1

-213

2

+140

Asian Handicap

1 Hcp -0.5

-100

2 Hcp +0.5

-130

Total Goals

Under 2.5

+110

Over 2.5

-152

Both Teams to Score

Yes

-189

No

+125

João Galvão is priced at +330 when it comes to First Goalscorer which makes him the favourite, while he’s also available at odds of +115 to find the net anytime.

João Galvão (San Luis)

First

+115

Anytime

+330

Diber Armando Cambindo (León)

First

+200

Anytime

+575

Fidel Barajas (San Luis)

First

+220

Anytime

+650

Ismael Díaz (León)

First

+240

Anytime

+650

Santiago Muñoz (San Luis)

First

+250

Anytime

+650

Rogelio Funes Mori (León)

First

+250

Anytime

+700

Jesús Medina (San Luis)

First

+280

Anytime

+750

David Rodríguez (San Luis)

First

+300

Anytime

+850

Benjamín Galdames (San Luis)

First

+370

Anytime

+1050

Jordi Cortizo de la Piedra (León)

First

+500

Anytime

+1300

Rodrigo Echeverría (León)

First

+540

Anytime

+1500

Fernando Beltrán (León)

First

+575

Anytime

+1600

Ángel Estrada (León)

First

+575

Anytime

+1600

Roberto Meraz (San Luis)

First

+600

Anytime

+1600

Julio Domínguez (San Luis)

First

+600

Anytime

+1700

Juan Domínguez (León)

First

+650

Anytime

+1800

Eduardo Aguila (San Luis)

First

+800

Anytime

+2200

Salvador Reyes (León)

First

+800

Anytime

+2200

Iván Moreno (León)

First

+800

Anytime

+2200

San Luis have clocked up six losses, three wins and one draw in the past 10 home games, recording an average of 1.70 goals per match and conceding 1.50.

León have not won in the past ten away matches. La Fiera have managed nine losses and one draw in the last 10 away matches, recording an average of 0.40 goals per game and conceding 2.30.

León were 2-1 victors against San Luis last time out at Estadio Alfonso Lastras. The previous 7 H2H games at Estadio Alfonso Lastras have featured four San Luis wins and three León triumphs.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
San Luis Home Stats		3-1-6	3.20	1.70	1.50	6	4	6	4
León Away Stats		0-1-9	2.70	0.40	2.30	3	7	3	7

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

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San Luis vs León Lineups & Team News

Avoid surprises — review the San Luis vs León team news before you bet. Get the predicted and confirmed Liga MX lineups plus the latest injury updates from us.

San Luis Team Page León Team Page

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