Southampton vs Middlesbrough Prediction, Betting Tips, Lineups & Odds | 27 Sep 2025

Championship Betting Preview: Southampton vs Middlesbrough

Southampton host Middlesbrough in this Championship game at St. Mary's, with kick-off set for 10:00 on Saturday 27 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

We Predict a Close Encounter

Middlesbrough look a nice wager to topple Southampton and we can take them at -125 with a +0.25 goal headstart on the Asian Handicap. This means dividing our stake equally between 0 and +0.5 in the hope of a payout.

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Most Recent H2H Clash Ended 1-1

Southampton lost away from home in their last Championship game. Hull City won 3-1 at MKM Stadium. The Saints recorded four shots on target and boasted 71% possession, while Adam Armstrong registered the goal.

Four days ago, Southampton visited Liverpool in the EFL Cup and were defeated 2-1.

Middlesbrough won their previous game, beating West Bromwich Albion at home. It was a 2-1 win at Riverside Stadium. Rob Edwards' team were restricted to 41% possession and recorded four shots on goal, with David Strelec and Kaly Sene on the scoresheet.

Head-to-Head Statistics

When the teams last went head-to-head, we saw Middlesbrough draw 1-1 away to Southampton at St. Mary's.

Championship		G	W	D	L	GF	GA	GD	GD	P
1	Middlesbrough	6	5	1	0	11	4	7	11:4	16
19	Southampton	6	1	3	2	7	9	-2	7:9	6

View Full Table

Southampton have 1 win, 5 losses and 4 draws, averaging 0.8 goals from 3.3 shots on goal and 11.4 attempts. The South Coast side have averaged 53.4% possession and 5.5 corners per game, with their opponents scoring 1.5 goals from 3.7 shots on goal, 14.5 attempts and 5.4 corners.

Top goalscorer Ryan Manning has found the net 2 times, with Adam Armstrong, Cameron Archer, Taylor Harwood-Bellis and Jay Robinson scoring 1 each. Ryan Fraser and Mateus Fernandes have racked up the most assists with 2, while goalkeeper Aaron Ramsdale has one clean sheet.

Middlesbrough have won 6, lost 2 and drawn 2, with an average of 1.4 goals from 11.3 attempts and 5.0 shots on goal. There’s been an average of 53.4% possession, 6.4 corners awarded and 4.1 corners against them, while they’ve conceded 0.9 goals from 10.8 attempts and 3.4 shots on goal.

Tommy Conway and Finn Azaz have top scored with 3, while David Strelec is next on 1. Hayden Hackney has been the chief assist maker in the previous 10 games with 3.

Predicted & Confirmed Lineups

Southampton predicted lineup (4-2-3-1): Gavin Bazunu (GK), Mads Roerslev, Joshua Quarshie, Jack Stephens, Ryan Manning, Flynn Downes, Shea Charles, Adam Armstrong, Finn Azaz, Ryan Fraser, Damion Downs.

Middlesbrough predicted lineup (3-4-2-1): Solomon Brynn (GK), Luke Ayling, Dael Fry, Alfie Jones, Callum Brittain, Aidan Morris, Hayden Hackney, Matthew Targett, Sverre Nypan, Tommy Conway, David Strelec.

Southampton vs Middlesbrough Prediction & Betting Tips

Get set for Southampton vs Middlesbrough with our full betting breakdown, complete with an expert match prediction, a likely final score, top corners play, player prop picks and a value-driven bet builder.

Match Prediction

When Middlesbrough kick off this Championship match, we will wager them at -125 on the Asian Handicap +0.25. Avoiding defeat seems well within their capability and a win could be on the cards.

It's essential to know the players who are missing for the next clash along with the form for each of the two sides. If you’re looking for the best Championship stats, we will showcase them and they provide the foundation for our football picks.

Key Southampton vs Middlesbrough league stats:

• The +0.25 line has been covered by Middlesbrough in 6 consecutive games.
• The +0.25 line has been covered by Middlesbrough in 8 of their last 10 games.
• The +0.25 line has been covered by Middlesbrough in 14 of their last 20 games.
• The -0.25 line hasn’t been covered by Southampton in 5 consecutive games.

Boro +0.25 Probability

The betting odds at the top bookies suggest our pick carries a 55.6% chance of winning. After careful examination, our tipsters calculate this probability to be somewhere between 60-65%. This is why we regard this as a value bet.

If you’re in search of a larger price, there are lots of options for those wanting to sell goals. The wager is riskier but will provide a bigger reward should it win.

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Our Match Prediction

Middlesbrough Asian Hcp +0.25 @ -125 Watch Live Bet Now

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Correct Score Prediction

Southampton 1 - 2 Middlesbrough

A 2-1 win in favor of Middlesbrough is available at odds of +850. Take a chance on the correct score and get rewarded for predicting the right scoreline.

Player Prop Picks

Top Pick: David Strelec Over 0.5 Shots On Target -161

David Strelec (Middlesbrough) can be backed to register a minimum of one shot on goal at -161. He stands out as a value pick when it comes to Shots on Target, with the recommendation being to wager this player prop pick.

Latest David Strelec Player Prop Odds

Goalscorer

Anytime

+230

First

+500

Shots On Target

Over 0.5

-161

Under 0.5

+102

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Tommy Conway to Score +225

Tommy Conway (Middlesbrough) has netted two goals in his past five Championship matches. We think there’s value in backing him for an Anytime Goalscorer prop bet at +225 which will hopefully see him find the net.

Latest Tommy Conway Player Prop Odds

Goalscorer

Anytime

+225

First

+500

Shots On Target

Over 0.5

-175

Under 0.5

+112

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Corners Prediction

Southampton To Have Most Corners -119

Southampton have been awarded the most corners in six consecutive games. Southampton should be capable of winning this Corner Match Bet and the odds of -119 look value.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Southampton

Total

10.90 5.50 5.40

Home

11.10 4.10 7.00

Away

7.80 4.20 3.60

Middlesbrough

Total

10.50 6.40 4.10

Home

9.80 6.30 3.50

Away

9.40 4.50 4.90

Latest Corner Odds

Total Corners

Over 9.5

-147

Under 9.5

+102

Southampton Corners

Over 5.5

+110

Under 5.5

-150

Middlesbrough Corners

Over 4.5

-110

Under 4.5

-125

Most Corners

1

-119

X

+650

2

+130

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Southampton vs Middlesbrough Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Game Could Go Right to the Wire According to the Bookies

Southampton are available at +130 to come away with a triumph in this Championship clash, meaning a 43% likelihood of winning according to the published betting odds. If you’re interested in wagering Middlesbrough, you can get +188 for the underdog.

There’s sometimes a case for betting on the Draw No Bet market, with Southampton available at -147 for those who want insurance on their bet. The same applies to opponents Middlesbrough at +108.

The Total Goals market reveals that Over 2.5 Goals is the current betting favourite. If you are expecting both teams to score, there’s the chance to back Yes at -164 on the BTTS market.

The best football betting sites definitely give customers lots of choice. When it comes to Championship matches, choose from hundreds of markets until you find the most attractive odds.

Full-Time Result

1

+130

X

+255

2

+188

Half-Time Result

1

+188

X

+123

2

+230

Double Chance

1X

-263

12

-370

X2

-179

Draw No Bet

1

-147

2

+108

Asian Handicap

1 Hcp -0.25

-100

2 Hcp +0.25

-125

Total Goals

Under 2.5

+102

Over 2.5

-132

Both Teams to Score

Yes

-164

No

+118

Adam Armstrong Shortest Odds for First Goalscorer

There is +220 available that Adam Armstrong finds the net, while he is available at +510 to register the first goal which makes him favourite.

Adam Armstrong (Southampton)

First

+220

Anytime

+510

Tommy Conway (Middlesbrough)

First

+225

Anytime

+500

David Strelec (Middlesbrough)

First

+230

Anytime

+500

Cameron Archer (Southampton)

First

+240

Anytime

+575

Ross Cameron Stewart (Southampton)

First

+245

Anytime

+600

Leo Scienza (Southampton)

First

+320

Anytime

+700

Samuel Silvera (Middlesbrough)

First

+330

Anytime

+800

Finn Azaz (Southampton)

First

+360

Anytime

+900

Micah Hamilton (Middlesbrough)

First

+380

Anytime

+950

Morgan Whittaker (Middlesbrough)

First

+400

Anytime

+1000

Sontje Hansen (Middlesbrough)

First

+410

Anytime

+950

Delano Burgzorg (Middlesbrough)

First

+450

Anytime

+1000

Ryan Fraser (Southampton)

First

+460

Anytime

+1000

Alex Gilbert (Middlesbrough)

First

+475

Anytime

+1050

Hayden Hackney (Middlesbrough)

First

+475

Anytime

+1150

Tom Fellows (Southampton)

First

+525

Anytime

+1200

Shea Charles (Southampton)

First

+550

Anytime

+1300

Caspar Jander (Southampton)

First

+800

Anytime

+1800

Nathan Wood (Southampton)

First

+850

Anytime

+2200

Mads Roerslev Rasmussen (Southampton)

First

+900

Anytime

+2000

Aidan Morris (Middlesbrough)

First

+900

Anytime

+2000

Elias Jelert (Southampton)

First

+950

Anytime

+2200

Adam Armstrong (Southampton)

Over 0.5

-182

Under 0.5

+117

Tommy Conway (Middlesbrough)

Over 0.5

-175

Under 0.5

+112

David Strelec (Middlesbrough)

Over 0.5

-161

Under 0.5

+102

Ross Cameron Stewart (Southampton)

Over 0.5

-149

Under 0.5

-114

Cameron Archer (Southampton)

Over 0.5

-143

Under 0.5

-118

Leo Scienza (Southampton)

Over 0.5

-108

Under 0.5

-143

Finn Azaz (Southampton)

Over 0.5

+110

Under 0.5

-167

Samuel Silvera (Middlesbrough)

Over 0.5

+112

Under 0.5

-182

Micah Hamilton (Middlesbrough)

Over 0.5

+117

Under 0.5

-179

Morgan Whittaker (Middlesbrough)

Over 0.5

+120

Under 0.5

-192

Sontje Hansen (Middlesbrough)

Over 0.5

+120

Under 0.5

-200

Delano Burgzorg (Middlesbrough)

Over 0.5

+132

Under 0.5

-213

Hayden Hackney (Middlesbrough)

Over 0.5

+132

Under 0.5

-217

Ryan Fraser (Southampton)

Over 0.5

+155

Under 0.5

-244

Alex Gilbert (Middlesbrough)

Over 0.5

+155

Under 0.5

-263

Tom Fellows (Southampton)

Over 0.5

+175

Under 0.5

-294

Shea Charles (Southampton)

Over 0.5

+200

Under 0.5

-345

Nathan Wood (Southampton)

Over 0.5

+300

Under 0.5

-667

Mads Roerslev Rasmussen (Southampton)

Over 0.5

+300

Under 0.5

-625

Past Ten Southampton Home Games Have Seen Six Defeats

Southampton have recorded six defeats, three draws and one victory in the previous 10 home matches, netting an average of 0.70 goals per game and conceding 1.70.

Middlesbrough haven’t lost any of their past three away games. The Teeside outfit have racked up four wins, four defeats and two draws in the last 10 away matches, scoring an average of 1.30 goals per game and conceding 1.00.

Southampton were involved in a 1-1 draw when last meeting Middlesbrough at St. Mary's.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Southampton Home Stats		1-3-6	2.40	0.70	1.70	7	3	6	4
Middlesbrough Away Stats		4-2-4	2.30	1.30	1.00	5	5	4	6

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

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Southampton vs Middlesbrough Lineups & Team News

Know who’s in and who’s out for Southampton vs Middlesbrough before making your bets. We’ll update you with predicted and confirmed Championship lineups plus current injury reports.

Southampton Team Page Middlesbrough Team Page