Southampton vs Middlesbrough Prediction, Betting Tips, Lineups & Odds | 27 Sep 2025

Championship Betting Preview: Southampton vs Middlesbrough

Southampton host Middlesbrough in this Championship game at St. Mary's, with kick-off set for 10:00 on Saturday 27 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

Middlesbrough look a nice wager to topple Southampton and we can take them at -125 with a +0.25 goal headstart on the Asian Handicap. This means dividing our stake equally between 0 and +0.5 in the hope of a payout.

Southampton lost away from home in their last Championship game. Hull City won 3-1 at MKM Stadium. The Saints recorded four shots on target and boasted 71% possession, while Adam Armstrong registered the goal.

Four days ago, Southampton visited Liverpool in the EFL Cup and were defeated 2-1.

Middlesbrough won their previous game, beating West Bromwich Albion at home. It was a 2-1 win at Riverside Stadium. Rob Edwards' team were restricted to 41% possession and recorded four shots on goal, with David Strelec and Kaly Sene on the scoresheet.

Head-to-Head Statistics

When the teams last went head-to-head, we saw Middlesbrough draw 1-1 away to Southampton at St. Mary's.

Championship		G	W	D	L	GF	GA	GD	GD	P
4	Southampton	46	22	14	10	82	56	26	82:56	80
5	Middlesbrough	46	22	14	10	72	47	25	72:47	80

View Full Table

Southampton have 1 win, 5 losses and 4 draws, averaging 0.8 goals from 3.3 shots on goal and 11.4 attempts. The South Coast side have averaged 53.4% possession and 5.5 corners per game, with their opponents scoring 1.5 goals from 3.7 shots on goal, 14.5 attempts and 5.4 corners.

Top goalscorer Ryan Manning has found the net 2 times, with Adam Armstrong, Cameron Archer, Taylor Harwood-Bellis and Jay Robinson scoring 1 each. Ryan Fraser and Mateus Fernandes have racked up the most assists with 2, while goalkeeper Aaron Ramsdale has one clean sheet.

Middlesbrough have won 6, lost 2 and drawn 2, with an average of 1.4 goals from 11.3 attempts and 5.0 shots on goal. There’s been an average of 53.4% possession, 6.4 corners awarded and 4.1 corners against them, while they’ve conceded 0.9 goals from 10.8 attempts and 3.4 shots on goal.

Tommy Conway and Finn Azaz have top scored with 3, while David Strelec is next on 1. Hayden Hackney has been the chief assist maker in the previous 10 games with 3.

Confirmed Lineups

Southampton confirmed lineup (4-2-3-1): Alex McCarthy (GK), Ronnie Edwards, Nathan Wood, Joshua Quarshie, Ryan Manning, Caspar Jander, Shea Charles, Tom Fellows, Finn Azaz, Adam Armstrong, Ross Stewart.

Middlesbrough confirmed lineup (3-4-2-1): Solomon Brynn (GK), Luke Ayling, George Edmundson, Alfie Jones, Callum Brittain, Aidan Morris, Hayden Hackney, Matt Targett, Morgan Whittaker, Tommy Conway, David Strelec.

Southampton vs Middlesbrough Prediction & Betting Tips

Get set for Southampton vs Middlesbrough with our full betting breakdown, complete with an expert match prediction, a likely final score, top corners play, player prop picks and a value-driven bet builder.

Match Prediction

When Middlesbrough kick off this Championship match, we will wager them at -125 on the Asian Handicap +0.25. Avoiding defeat seems well within their capability and a win could be on the cards.

It's essential to know the players who are missing for the next clash along with the form for each of the two sides. If you’re looking for the best Championship stats, we will showcase them and they provide the foundation for our football picks.

Key Southampton vs Middlesbrough league stats:

• The +0.25 line has been covered by Middlesbrough in 6 consecutive games.
• The +0.25 line has been covered by Middlesbrough in 8 of their last 10 games.
• The +0.25 line has been covered by Middlesbrough in 14 of their last 20 games.
• The -0.25 line hasn’t been covered by Southampton in 5 consecutive games.

The betting odds at the top bookies suggest our pick carries a 55.6% chance of winning. After careful examination, our tipsters calculate this probability to be somewhere between 60-65%. This is why we regard this as a value bet.

If you’re in search of a larger price, there are lots of options for those wanting to sell goals. The wager is riskier but will provide a bigger reward should it win.

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Our Match Prediction

Middlesbrough Asian Hcp +0.25 @ -125 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Sep 25, 16:08). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Southampton 1 - 2 Middlesbrough

A 2-1 win in favor of Middlesbrough is available at odds of +900. Take a chance on the correct score and get rewarded for predicting the right scoreline.

Player Prop Picks

Top Pick: David Strelec Over 0.5 Shots On Target -161

David Strelec (Middlesbrough) can be backed to register a minimum of one shot on goal at -161. He stands out as a value pick when it comes to Shots on Target, with the recommendation being to wager this player prop pick.

Latest David Strelec Player Prop Odds

Goalscorer

Anytime

+250

First

+525

Shots On Target

Over 0.5

-149

Under 0.5

-105

Shots

Over 2.5

+123

Under 2.5

-

---

Tommy Conway to Score +225

Tommy Conway (Middlesbrough) has netted two goals in his past five Championship matches. We think there’s value in backing him for an Anytime Goalscorer prop bet at +225 which will hopefully see him find the net.

Latest Tommy Conway Player Prop Odds

Goalscorer

Anytime

+250

First

+550

Shots On Target

Over 0.5

-154

Under 0.5

-102

Shots

Over 2.5

+107

Under 2.5

-

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Corners Prediction

Southampton To Have Most Corners -119

Southampton have been awarded the most corners in six consecutive games. Southampton should be capable of winning this Corner Match Bet and the odds of -119 look value.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Southampton

Total

11.50 5.80 5.70

Home

10.50 5.60 4.90

Away

11.00 5.40 5.60

Middlesbrough

Total

12.70 9.30 3.40

Home

13.00 9.60 3.40

Away

9.80 5.20 4.60

Latest Corner Odds

Total Corners

Over 9.5

-132

Under 9.5

-108

Southampton Corners

Over 5.5

-100

Under 5.5

-138

Middlesbrough Corners

Over 4.5

-100

Under 4.5

-138

Most Corners

1

-200

X

+650

2

+215

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Southampton vs Middlesbrough Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Southampton are available at +114 to come away with a triumph in this Championship clash, meaning a 47% likelihood of winning according to the published betting odds. If you’re interested in wagering Middlesbrough, you can get +225 for the underdog.

There’s sometimes a case for betting on the Draw No Bet market, with Southampton available at -179 for those who want insurance on their bet. The same applies to opponents Middlesbrough at +130.

The Under 2.5 / Over 2.5 Goals betting market suggests that there’s not much between the two options. If you are expecting both teams to score, there’s the chance to back Yes at -149 on the BTTS market.

The best football betting sites definitely give customers lots of choice. When it comes to Championship matches, choose from hundreds of markets until you find the most attractive odds.

Full-Time Result

1

+114

X

+245

2

+225

Half-Time Result

1

+170

X

+123

2

+255

Double Chance

1X

-313

12

-357

X2

-154

Draw No Bet

1

-179

2

+130

Asian Handicap

1 Hcp -0.25

-116

2 Hcp +0.25

-106

Total Goals

Under 2.5

-106

Over 2.5

-120

Both Teams to Score

Yes

-149

No

+108

There is +220 available that Adam Armstrong finds the net, while he is available at +500 to register the first goal which makes him favourite.

Adam Armstrong (Southampton)

First

+220

Anytime

+500

Ross Cameron Stewart (Southampton)

First

+235

Anytime

+575

Cameron Archer (Southampton)

First

+240

Anytime

+575

David Strelec (Middlesbrough)

First

+250

Anytime

+525

Tommy Conway (Middlesbrough)

First

+250

Anytime

+550

Leo Scienza (Southampton)

First

+310

Anytime

+700

Finn Azaz (Southampton)

First

+350

Anytime

+800

Samuel Silvera (Middlesbrough)

First

+350

Anytime

+850

Sontje Hansen (Middlesbrough)

First

+420

Anytime

+1000

Micah Hamilton (Middlesbrough)

First

+420

Anytime

+1000

Morgan Whittaker (Middlesbrough)

First

+440

Anytime

+1050

Ryan Fraser (Southampton)

First

+460

Anytime

+1050

Delano Burgzorg (Middlesbrough)

First

+460

Anytime

+1050

Hayden Hackney (Middlesbrough)

First

+500

Anytime

+1200

Alex Gilbert (Middlesbrough)

First

+525

Anytime

+1200

Tom Fellows (Southampton)

First

+525

Anytime

+1200

Shea Charles (Southampton)

First

+550

Anytime

+1300

Caspar Jander (Southampton)

First

+700

Anytime

+1700

Mads Roerslev Rasmussen (Southampton)

First

+850

Anytime

+1900

Nathan Wood (Southampton)

First

+850

Anytime

+1900

Elias Jelert (Southampton)

First

+950

Anytime

+2200

Aidan Morris (Middlesbrough)

First

+1000

Anytime

+2200

Adam Armstrong (Southampton)

Over 0.5

-185

Under 0.5

+115

Ross Cameron Stewart (Southampton)

Over 0.5

-156

Under 0.5

-109

Tommy Conway (Middlesbrough)

Over 0.5

-154

Under 0.5

-102

David Strelec (Middlesbrough)

Over 0.5

-149

Under 0.5

-105

Cameron Archer (Southampton)

Over 0.5

-143

Under 0.5

-118

Leo Scienza (Southampton)

Over 0.5

-115

Under 0.5

-135

Finn Azaz (Southampton)

Over 0.5

+105

Under 0.5

-164

Samuel Silvera (Middlesbrough)

Over 0.5

+123

Under 0.5

-200

Micah Hamilton (Middlesbrough)

Over 0.5

+125

Under 0.5

-200

Morgan Whittaker (Middlesbrough)

Over 0.5

+130

Under 0.5

-208

Sontje Hansen (Middlesbrough)

Over 0.5

+133

Under 0.5

-213

Delano Burgzorg (Middlesbrough)

Over 0.5

+140

Under 0.5

-227

Hayden Hackney (Middlesbrough)

Over 0.5

+145

Under 0.5

-238

Ryan Fraser (Southampton)

Over 0.5

+150

Under 0.5

-250

Alex Gilbert (Middlesbrough)

Over 0.5

+170

Under 0.5

-286

Tom Fellows (Southampton)

Over 0.5

+180

Under 0.5

-313

Shea Charles (Southampton)

Over 0.5

+200

Under 0.5

-357

Mads Roerslev Rasmussen (Southampton)

Over 0.5

+290

Under 0.5

-588

Nathan Wood (Southampton)

Over 0.5

+300

Under 0.5

-625

Adam Armstrong (Southampton)

Over 2.5

-118

Under 2.5

-

Ross Cameron Stewart (Southampton)

Over 2.5

+105

Under 2.5

-

Cameron Archer (Southampton)

Over 2.5

+125

Under 2.5

-

David Strelec (Middlesbrough)

Over 2.5

+123

Under 2.5

-

Tommy Conway (Middlesbrough)

Over 2.5

+107

Under 2.5

-

Leo Scienza (Southampton)

Over 1.5

-182

Under 1.5

-

Finn Azaz (Southampton)

Over 1.5

-135

Under 1.5

-

Samuel Silvera (Middlesbrough)

Over 1.5

-100

Under 1.5

-

Sontje Hansen (Middlesbrough)

Over 1.5

+108

Under 1.5

-

Micah Hamilton (Middlesbrough)

Over 1.5

-105

Under 1.5

-

Morgan Whittaker (Middlesbrough)

Over 1.5

-120

Under 1.5

-

Ryan Fraser (Southampton)

Over 1.5

+130

Under 1.5

-

Delano Burgzorg (Middlesbrough)

Over 1.5

-105

Under 1.5

-

Hayden Hackney (Middlesbrough)

Over 1.5

-111

Under 1.5

-

Alex Gilbert (Middlesbrough)

Over 1.5

+145

Under 1.5

-

Shea Charles (Southampton)

Over 0.5

-244

Under 0.5

-

Stats: Championship matches only
Southampton have recorded six defeats, three draws and one victory in the previous 10 home matches, netting an average of 0.70 goals per game and conceding 1.70.

Middlesbrough haven’t lost any of their past three away games. The Teeside outfit have racked up four wins, four defeats and two draws in the last 10 away matches, scoring an average of 1.30 goals per game and conceding 1.00.

Southampton were involved in a 1-1 draw when last meeting Middlesbrough at St. Mary's.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Southampton Home Stats		7-3-0	2.90	2.10	0.80	6	4	6	4
Middlesbrough Away Stats		5-4-1	3.50	2.10	1.40	9	1	8	2

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

Southampton vs Middlesbrough Lineups & Team News

Know who’s in and who’s out for Southampton vs Middlesbrough before making your bets. We’ll update you with predicted and confirmed Championship lineups plus current injury reports.

Southampton Team Page Middlesbrough Team Page

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