St. Louis City vs San Diego Prediction, Betting Tips, Lineups & Odds | 10 May 2025

We’re Going Over With Our Total Goals Bet

St. Louis and San Diego could score a few goals between them and we’re keen to back the -154 when it comes to Over 2.5. This can be wagered with confidence on the Total Goals market and we’re expecting a payout.

Goalless Draw in Pair’s Last Encounter

St. Louis City lost away from home in their last game. Seattle Sounders won 4-1 at Lumen Field. The Missouri club recorded 43% possession and had four shots on target, while Marcel Hartel bagged the goal.

San Diego FC have lost their previous three road games. Their latest appearance was a 5-0 home win at Snapdragon Stadium against Dallas. Mikey Varas' side had nine shots on goal and boasted 61% possession, while Hirving Lozano scored twice.

Head-to-Head Statistics

The last head-to-head saw home team San Diego draw 0-0 with St. Louis at Snapdragon Stadium.

MLS		G	W	D	L	GF	GA	GD	GD	P
2	San Diego	22	13	3	6	46	30	16	46:30	42
28	St. Louis	22	4	6	12	23	35	-12	23:35	18

View Full Table

2 wins, 5 losses and 3 draws, averaging 0.8 goals from 7.4 attempts and 3.6 shots on goal. St. Louis have had 41.1% possession and 3.8 corners per match. On average, they have conceded 1.2 goals from 11.8 attempts and 5.2 shots on goal, while their opponents have earned 5.9 corners.

Top scorers are Marcel Hartel and Cedric Teuchert on 2 goals, while Joao Klauss has racked up 1. The top assist makers are Jannes-Kilian Horn, Celio Pompeu and Henry Kessler, all of whom have 1 on the board.

SDFC have 4 victories, 4 defeats and 2 draws, with an average of 1.9 goals from 4.8 shots on goal and 9.5 attempts. The Southern California outfit have averaged 58.1% possession, 5.0 corners awarded and 2.9 corners against, while they’ve conceded 1.5 goals from 4.8 shots on goal and 9.5 attempts.

Hirving Lozano is top of the team’s scoring charts with 4, Onni Valakari has 3, with Anders Dreyer and Luca de la Torre both on 2. Anders Dreyer has managed 5 assists in the last 10 games.

Confirmed Lineups

St. Louis City confirmed lineup (4-3-3): Benjamin Lundt (GK), Timo Baumgartl, Kyle Hiebert, Joshua Yaro, Akil Watts, Conrad Wallem, Jannes-Kilian Horn, Tomas Ostrak, Cedric Teuchert, Marcel Hartel, Joao Klauss.

San Diego confirmed lineup (4-3-3): Carlos Dos Santos (GK), William Kumado, Christopher McVey, Patrick McNair, Luca Bombino, Anibal Godoy, Jeppe Tverskov, Luca de la Torre, Anders Dreyer, Onni Valakari, Hirving Lozano.

St. Louis City vs San Diego Prediction & Betting Tips

We can’t pass up the chance to back Over 2.5 Goals, with this MLS encounter set to feature a combined three goals or more. Take odds of -154 that this outcome happens with confidence.

The formbook is always a good place to start ahead of making football predictions. Team news is also an important port of call, while the stats we present always tell an interesting story.

Key St. Louis City vs San Diego league stats:

• The 2.5 line has been covered in 6 of the last 10 St. Louis games at home.
• The 2.5 line has been covered in 12 of the last 20 St. Louis games.
• The 2.5 line has been covered in the last 2 St. Louis games.
• The 2.5 line has been covered in all of the last 5 SDFC games.
• The 2.5 line has been covered in 8 of the last 10 SDFC games.
• The 2.5 line has been covered in the last 7 SDFC games.

Over 2.5 Probability

The latest odds imply that our pick has a 60.6% prospect of winning. After careful examination, our tipsters have this probability somewhere between 65-70%. It is therefore regarded as a value bet.

If you’re looking for bigger odds for your Total Goals pick, then why not consider Over 3.5. It’s a great alternative wager where you need four or more to be scored in order for the bet to land.

Our Match Prediction

Over 2.5 Goals @ -154 Bet Now

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Correct Score Prediction

St. Louis 1 - 2 San Diego

We’re betting on San Diego to secure a 2-1 winning scoreline. Odds of +750 can be taken and it’s great fun to predict a correct score and hopefully land a winner.

Corners Prediction

Under 9.5 Corners -120

It has now been seven straight San Diego matches where the 9.5 Total Corners line has not been covered. There’s the opportunity to go under the Total Corners line and we’re expecting this to happen, with odds of -120 on offer.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

St. Louis

Total

9.70 3.80 5.90

Home

9.90 4.40 5.50

Away

9.40 3.50 5.90

San Diego

Total

7.90 5.00 2.90

Home

8.17 5.50 2.67

Away

6.80 4.00 2.80

Latest Corner Odds

Total Corners

Over 9.5

-100

Under 9.5

-138

St. Louis Corners

Over 4.5

-110

Under 4.5

-125

San Diego Corners

Over 4.5

-120

Under 4.5

-120

Most Corners

1

-114

X

+540

2

+112

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St. Louis City vs San Diego Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Latest Odds Suggest a Close Encounter

You can get MLS betting odds of +145 for a St. Louis City win and the bookies have San Diego available at +150. If you want to back the draw, it’s on offer at +280.

The Over 2.5 Goals option is currently favourite on the Total Goals market.

There are hundreds of markets when it comes to betting on the MLS coupon and we recommend visiting the leading betting sites to find the bet that matches your view on the game.

Full-Time Result

1

+145

X

+280

2

+150

Half-Time Result

1

+200

X

+137.5

2

+210

Double Chance

1X

-200

12

-400

X2

-188

Draw No Bet

1

-120

2

-120

Asian Handicap

1 Hcp 0.0

-111

2 Hcp 0.0

-111

Total Goals

Under 2.5

+135

Over 2.5

-175

Both Teams to Score

Yes

-188

No

+137.5

St. Louis City vs San Diego Lineups & Team News

It’s good to know about any injuries and this is reflected in our St. Louis vs SDFC team news, with this leading to predicted and confirmed lineups.

The MLS squad information is a great asset when it comes to making your bets.

St. Louis City Team Page San Diego Team Page