St Louis Blues vs Buffalo Sabres Prediction, Picks & Odds | 06 Nov 2025

NHL Betting Preview: Blues vs Sabres

The St Louis Blues face off against the Buffalo Sabres at KeyBank Center, with face-off scheduled for 19:00 on Thursday, November 6. Our betting preview features expert NHL predictions, betting tips, the latest odds, H2H stats, player stats, team news and the starting lineups.

It’s time to side with the Sabres to secure a victory over the Blues. They should have the upper hand and the -141 for our Moneyline prediction looks a great price.

St Louis Blues have now lost four straight road games. When they last took to the ice, Washington Capitals won 6-1 at Capital One Arena. Alexey Toropchenko was the solitary scorer after Blues registered 24 shots.

Buffalo Sabres were beaten 2-1 (OT) at KeyBank Center in their last game, being turned over at home to Utah Mammoth. Noah Oestlund scored the only goal, with Alex Lyon recording 33 saves (.943).

Head-to-Head Statistics

The Sabres have beaten the Blues in the last two encounters. A 4-3 (OT) victory at KeyBank Center was followed by a 4-2 win at Enterprise Center. The past 10 H2H clashes have seen both teams record five wins.

Starting Goalies

Joel Hofer (Confirmed)

Season	W-L-OTL:	GAA:	SV%:	SO:
24/25	19-12-5	2.6	.908	6
23/24	15-12-1	2.65	.913	1

Ukko-Pekka Luukkonen (Confirmed)

Season	W-L-OTL:	GAA:	SV%:	SO:
24/25	18-8-3	2.6	.910	1
23/24	27-22-4	2.57	.910	5

2 wins, 6 losses and 2 overtime losses, averaging 2.6 goals from 26.3 shots on goal, with a 20.0% powerplay efficiency. The Blues have given up 4.1 goals from 25.7 shots, averaging 3.1 penalties with a penalty-killing efficiency of 71.0%.

Pius Suter is the top points scorer with 7 points, 4 goals and 3 assists, with Jordan Kyrou racking up 6 points, 4 goals and 2 assists, over the last 10 games. Goalie Jordan Binnington have a 3.25 goal against average with a .859 save percentage.

The Sabres have 5 wins, 1 loss and 4 overtime losses, averaging 3.5 goals from 29.7 shots on goal, with a 18.2% powerplay efficiency. They have conceded 3.0 goals from 31.8 shots, averaging 4.8 penalties per game with a penalty-killing efficiency of 91.7%.

The top points scorer is Alex Tuch with 11 points, 5 goals and 6 assists, while Tage Thompson is next in line after registering 9 points, 4 goals and 5 assists. Goalie Alex Lyon have a 2.84 GAA with a .913 SV%, including one shutout.

St Louis Blues vs Buffalo Sabres Prediction & Picks

From our main match prediction to correct score advice, must-watch player props and a custom bet builder — this St Louis Blues vs Buffalo Sabres betting preview covers it all.

Game Prediction

There’s an attractive -141 that Buffalo Sabres are able to get the better of their opponents. This pick can be wagered on the Moneyline for this NHL encounter.

We only make our hockey predictions after confirming the latest team news. Studying recent form and digging into the most relevant NHL stats also helps us build a complete picture.

Key Blues vs Sabres stats:

• Sabres have won 13 of their last 20 games at home.
• Sabres have won 6 of their last 10 games at home.
• Blues have lost their last 4 games on the road.
• Blues have lost 8 of their last 10 games.
• Blues have lost 13 of their last 20 games.
• Sabres have won the last 2 games between these teams.

Sabres Moneyline Probability

Looking at the latest betting odds, there’s a 58.5% likelihood of our pick delivering a return. Our cappers think there’s a stronger chance of success and calculate the probability to be 65-70%. The bet can be recommended for this precise reason.

If you want more juice from a wager on Buffalo, there are several alternatives including 3-Way Moneyline. Puck Line and Winning Margin provide even greater flexibility for bettors.

Boost your wager with the newest free bets, sign-up promotions and the best betting offers featured in our easy-to-use guide.

Our Game Prediction

Sabres Moneyline @ -141 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Nov 6, 02:43). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Jimmy Snuggerud Over 1.5 Shots -164

Jimmy Snuggerud (Blues) has recorded Over 1.5 shots on goal in 5 straight games on the road. There is odds of -164 available when it comes to this Shots on Goal wager and we think he’ll cover the line.

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Blues 3 - 5 Sabres

A potentially entertaining bet is going for the Sabres to win by a 5-3 scoreline. At odds of +2000, there’s the chance to get a handsome return should this wager win.

Latest Correct Score Odds

Score

Blues

Sabres

1-0

Blues

+5500

Sabres

+5500

2-0

Blues

+5500

Sabres

+5000

2-1

Blues

+1600

Sabres

+1500

3-0

Blues

+4000

Sabres

+3000

3-1

Blues

+2000

Sabres

+1800

3-2

Blues

+900

Sabres

+850

4-0

Blues

+5000

Sabres

+3500

4-1

Blues

+1900

Sabres

+1500

4-2

Blues

+1700

Sabres

+1500

4-3

Blues

+1050

Sabres

+950

5-0

Blues

+9000

Sabres

+6000

5-1

Blues

+3000

Sabres

+2200

5-2

Blues

+1900

Sabres

+1500

5-3

Blues

+2500

Sabres

+2000

5-4

Blues

+2000

Sabres

+1800

6-0

Blues

+13000

Sabres

+9000

6-1

Blues

+7500

Sabres

+5000

6-2

Blues

+4000

Sabres

+2800

6-3

Blues

+3300

Sabres

+2500

6-4

Blues

+5000

Sabres

+4000

6-5

Blues

+4500

Sabres

+4500

7-0

Blues

+4500

Sabres

+14000

7-1

Blues

+12000

Sabres

+8000

7-2

Blues

+10000

Sabres

+6600

7-3

Blues

+6600

Sabres

+5000

7-4

Blues

+7000

Sabres

+5500

7-5

Blues

+11000

Sabres

+9000

7-6

Blues

+11000

Sabres

+11000

8-1

Blues

+11000

Sabres

+13000

8-2

Blues

+11000

Sabres

+11000

8-3

Blues

+11000

Sabres

+12000

8-4

Blues

+12500

Sabres

+10000

8-5

Blues

+14000

Sabres

+12500

View More

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

St Louis Blues vs Buffalo Sabres Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The Buffalo Sabres odds have been priced up by the sportsbooks and they are -145 betting favorites to land victory in this game which means a 59% chance of winning. St Louis Blues are regarded as a long shot to win and you can currently back them at +120.

The puck line is 1.5 and the total goals line is 6.5. The Totals offers hockey bettors an alternative way of getting involved. If you're keen on Over 6.5, this selection is available at -100.

From team props to game lines, National Hockey League wagering comes with no shortage of options. Head to the best betting apps to discover the market that fits your read on the game.

Moneyline

Blues

+120

Sabres

-145

3-Way Moneyline

Blues

+180

Tie

+330

Sabres

+116

Puck Line

Blues +1.5

-204

Sabres -1.5

+164

Total Goals

Under 6.5

-122

Over 6.5

-100

The best gambling sites offer player prop betting to their customers. Player and goalie props can be a great alternative if you want to focus on an individual’s performance within a game and it often involves wagering over or under a line.

It’s possible to use stats to your advantage when it comes to NHL micro betting, especially if you’re predicting outcomes such as the Next Goal and Next Goalscorer. Check out the live team and player props and see if you can find an angle.

Latest regular season and playoff games stats.

St Louis Blues Stats

Buffalo Sabres Stats

Moneyline

• 2 wins and 8 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 home games

Puck Line

• +1.5 Betting Line: Have covered the +1.5 puck line in 5 of the last 10 games
• +1.5 Betting Line on the Road: Have covered the +1.5 puck line in 5 of the last 10 games on the road

Puck Line

• -1.5 Betting Line: Have covered the -1.5 puck line in 4 of the last 10 games
• -1.5 Betting Line at Home: Have covered the -1.5 puck line in 4 of the last 10 home games

Total Goals

• Game Totals: An average of 6.80 goals in the previous 10 games
• Game Totals on the Road: An average of 7.00 goals in the previous 10 games on the road
• Over 6.5: Covered in 6 of the previous 10 games
• Over 6.5 on the Road: Covered in 7 of the previous 10 games on the road
• Team Totals: Have scored an average of 2.60 goals and allowed 4.20 goals in the last 10 games
• Team Totals on the Road: Have scored an average of 2.90 pts and allowed 4.10 goals in the last 10 games on the road

Total Goals

• Game Totals: An average of 6.60 goals in the previous 10 games
• Game Totals at Home: An average of 6.30 goals in the previous 10 home games
• Over 6.5: Covered in 6 of the previous 10 games
• Over 6.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 3.60 goals and allowed 3.00 goals in the last 10 games
• Team Totals at Home: Have scored an average of 3.40 goals and allowed 2.90 goals in the last 10 home games

Team Stats - Avg/Game

Last 10 Games

• Goals Powerplay: 0.7
• Shots: 26.3
• Goals Shorthanded: 0.1
• Penalties: 3.1
• Empty Net Goals: 0.1
• Penalty Minutes: 7.4
• Blocks: 14.2
• Faceoff Wins : 26.1
• Hits: 21.9
• Giveaways: 14.4
• Takeaways: 4.4

Last 10 Games on the Road

• Goals Powerplay: 0.7
• Shots: 27.1
• Goals Shorthanded: 0.1
• Penalties: 3.8
• Empty Net Goals: 0.1
• Penalty Minutes: 12.5
• Blocks: 17
• Faceoff Wins : 29.6
• Hits: 30.4
• Giveaways: 17.4
• Takeaways: 4.4

Team Stats - Avg/Game

Last 10 Games

• Goals Powerplay: 0.8
• Shots: 29.7
• Goals Shorthanded: 0.2
• Penalties: 4.8
• Empty Net Goals: 0.1
• Penalty Minutes: 12.1
• Blocks: 13.8
• Faceoff Wins : 24.9
• Hits: 19.4
• Giveaways: 13.8
• Takeaways: 4.4

Last 10 Home Games

• Goals Powerplay: 0.6
• Shots: 29.5
• Goals Shorthanded: 0.3
• Penalties: 4.6
• Empty Net Goals: 0.2
• Penalty Minutes: 10.3
• Blocks: 14.2
• Faceoff Wins : 25.6
• Hits: 18.3
• Giveaways: 13.7
• Takeaways: 4.5

Injuries & Suspensions

Starting Lineups

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