BYU vs East Carolina Prediction, Picks & Odds | 20 Sep 2025

College Football Betting Preview: BYU vs East Carolina

BYU square off against East Carolina in this NCAAF Week 4 matchup at Dowdy-Ficklen Stadium, with kickoff scheduled for 19:30 on Saturday, September 20. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.

We’re very confident of East Carolina staying close to BYU, with our prediction being that they’ll cover the spread. The +6.5 looks more than generous at -112.

Confident in our spread pick? Read the full review of BetMGM, then grab our exclusive promo code before placing your bet.

Brigham Young Cougars beat Stanford Cardinal in their previous game, making it back-to-back victories. It was a 27-3 home win at Lavell Edwards Stadium.

East Carolina Pirates made it back-to-back wins in their last game. It was a 38-0 road triumph at Brooks Stadium when meeting Coastal Carolina Chanticleers.

Head-to-Head Statistics

It was a 27-24 win for East Carolina at Lavell Edwards Stadium when they last played BYU.

BYU vs East Carolina Prediction & Picks

Head into BYU vs East Carolina with expert betting insights, including our main match prediction, best correct score pick and a value-driven bet builder. Dive into each section below for more.

Game Prediction

We’re really sweet on East Carolina putting up a fight in this college football matchup and that compels us to bet the underdogs against the spread. You can get -112 when it comes to the +6.5 that is available.

The formbook is always a smart starting point when making CFB predictions. Up-to-date team news is just as important, while the stats we provide often reveal valuable insights.

Key BYU vs East Carolina stats:

• The +6.5 line has been covered by East Carolina in 9 of their last 10 games at home.
• The +6.5 line has been covered by East Carolina in 16 of their last 20 games at home.
• The +6.5 line has been covered by East Carolina in 2 consecutive games.
• The -6.5 line hasn’t been covered by BYU in 7 of their last 10 games on the road.
• The -6.5 line hasn’t been covered by BYU in 14 of their last 20 games on the road.

East Carolina +6.5 Probability

The top sportsbooks imply that our pick has a 52.9% prospect of winning. After careful examination, our experts calculate this probability to be somewhere between 55-60%. It’s the reason why we are recommending this college bet.

If the initial odds don’t grab your fancy, there’s the option to shoot for more juice by moving the line when it comes to your spread pick. It all comes down to how confident you feel.

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Our Game Prediction

East Carolina +6.5 @ -112 Bet Now

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Correct Score Prediction

BYU 30 - 27 East Carolina

We’re expecting this to be a close matchup and we’ll take BYU to win 30-27. This is available at massive odds for those that want to have a speculative wager.

BYU vs East Carolina Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

For this college game, the sportsbooks’ Moneyline betting odds mean Brigham Young Cougars are -250 favorites to win and that means a 71% chance of landing a victory. For those wanting to oppose the market leader, you can get +202 about East Carolina.

There is a spread of 6.5 and total points has a line of 50.5. There is no denying the popularity of wagering on the Totals. If you’re going for Over 50.5, then the odds are -105.

Whether you are wagering pre-game or in-game on college football, the top betting apps let you feast on a wide range of team props and game lines. The selections are practically endless, and it’s awesome to have so many options at your fingertips.

Moneyline

BYU

-250

East Carolina

+202

Point Spread

BYU -6.5

-115

East Carolina +6.5

-105

Total Points

Under 50.5

-115

Over 50.5

-105

Should you be more interested in a specific individual who is competing, check out the gambling sites’ prop bets where you can pick out player and quarterback lines that focus on performance rather than the game result.

There are always opportunities to enjoy college football micro betting. It’s generally the case that you will find player and team props in-game and bettors can use their insight to wager on outcomes such as the Next Punt, Turnover or Score Play.

East Carolina Record Shows Five Wins in Last Ten at Home

East Carolina own a 5-5 mark in their past 10 home games, putting up 31.60 points on average and giving up 18.10.

BYU own a 6-4 mark in their past 10 games on the road, posting 25.10 points per contest while yielding 25.60.

Last 10 Games		W-L	P	PF	PA	O49.5	U49.5
East Carolina Home Stats		5-5	49.70	31.60	18.10	6	4
BYU Away Stats		6-4	50.70	25.10	25.60	5	5

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O49.5 = Games Over 49.5 Points
• U49.5 = Games Under 49.5 Points

Latest regular season and playoff games stats.

Brigham Young Cougars Stats

East Carolina Pirates Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 home games

Point Spread

• -6.5 Betting Line: Have covered the spread in 6 of the last 10 games
• -6.5 Betting Line on the Road: Have covered the spread in 3 of the last 10 games on the road

Point Spread

• +6.5 Betting Line: Have covered the spread in 7 of the last 10 games
• +6.5 Betting Line at Home: Have covered the spread in 9 of the last 10 home games

Total Points

• Game Totals: An average of 51.50 pts in the previous 10 games
• Game Totals on the Road: An average of 50.70 pts in the previous 10 games on the road
• Over 49.5: Covered in 6 of the previous 10 games
• Over 49.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 33.60 pts and allowed 17.90 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 25.10 pts and allowed 25.60 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 60.20 pts in the previous 10 games
• Game Totals at Home: An average of 49.70 pts in the previous 10 home games
• Over 49.5: Covered in 7 of the previous 10 games
• Over 49.5 at Home: Covered in 6 of the previous 10 home games
• Team Totals: Have scored an average of 36.80 pts and allowed 23.40 pts in the last 10 games
• Team Totals at Home: Have scored an average of 31.60 pts and allowed 18.10 pts in the last 10 home games

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