Central Michigan vs Pittsburgh Prediction, Picks & Odds | 06 Sep 2025
College Football Betting Preview: Central Michigan vs Pitt Panthers
Central Michigan go up against Pitt Panthers in this NCAAF Week 2 matchup at Acrisure Stadium, with kickoff scheduled for 12:00 on Saturday, September 6. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.
We’re predicting a one-sided affair when Pitt Panthers play Central Michigan. Take the favorites at -110 to cover an appealing -21.5 line on the spread.
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Central Michigan Chippewas got the win in their previous game. A 16-14 triumph occurred on the road at CEFCU Stadium when playing San Jose State Spartans.
Pittsburgh Panthers won their last game, beating Duquesne Dukes at home. It was a 61-9 win at Acrisure Stadium.
Central Michigan vs Pittsburgh Prediction & Picks
Our Central Michigan vs Pittsburgh betting outlook has it all, including a trusted match forecast, our predicted score, top player prop picks and a hand-picked bet builder.
Game Prediction
We strongly fancy the chances of Pitt Panthers beating the underdogs handsomely in this college football matchup. That is why we’re betting them at -21.5 on the spread at -110.
Team news and current form always play a key role in shaping our expert CFB predictions. We also dig into the latest stats and trends to help deliver the most accurate picks possible.
Key Central Michigan vs Pittsburgh stats:
Pitt -21.5 Probability
The top sportsbooks are estimating that there is a 52.4% likelihood of this pick winning. However, we think that the probability is close to 60% taking all factors into consideration. It's therefore regarded as a value wager.
If you want to back Pitt without taking them on the point spread, there’s the alternative to go for a Winning Margin wager instead. There are lots of different options here.
Before placing your bet, explore our exclusive betting promo codes, welcome offers, and best free bets for today.
Player Prop Picks
You can back Eli Holstein (Pitt) at -114 to exceed 262.5 passing yards. We’re happy to take him to cover the QB Passing Yards line and bettors can place this wager with confidence.
Desmond Reid (Pitt) is priced at -114 to accumulate over 75.5 rushing yards. The line for him on the Overs is highly appealing, with Player Rushing Yards bettors able to get plenty of juice.
Same Game Parlay Picks
Try out our same game parlay pick which starts with Pitt -21.5. We’ve also gone for Under 50.5 points and Eli Holstein (Pitt) to have Over 262.5 passing yards.
A same game parlay is an awesome way of cheering on different outcomes within the same football game. You can predict a number of outcomes and get bigger odds than a single wager. The odds can combine to great effect.
Correct Score Prediction
7
-
35
Pittsburgh
Should you wish to go for a speculative bet, try Pittsburgh to triumph 35-7 on the correct score lines. This should be a fun wager which could potentially yield a huge return.
Central Michigan vs Pittsburgh Odds
The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.
At betting odds of -2000 with the sportsbooks, Pittsburgh are regarded as 95% likely to win this college game. Central Michigan are the underdogs at +980 and they’re regarded as least likely to win.
The current spread is 21.5 and the total points line is 49.5. The beauty of the Totals is that you only have to choose from one of two options. Those that want to back Under 49.5 can find odds of -120 available.
When it comes to college football, the top betting apps deliver a wide variety of game lines and team props. With so many options available, it’s worth taking your time to find the wager that fits your view of the matchup.
There’s the chance to back Desmond Reid at +420 to be the First Touchdown Scorer. He’s the favorite and available at similar odds to record the last TD instead.
Touchdown
Receiving Yards
Rushing Yards
Micro betting provides a rollercoaster ride for college football bettors. It can be great to enjoy the live lines, with the opportunity to wager on the Next Scoring Play. Watch the live action before deciding which way to go.
Pitt Sitting on Seven Wins in Past Ten at Home
Pitt own a 7-3 mark in their past 10 home games, scoring 35.50 points per contest and conceding 20.00.
Central Michigan have one win and nine losses in the last 10 games on the road, putting up 17.30 points on average and giving up 33.70.
| Last 10 Games | W-L | P | PF | PA | O50.5 | U50.5 | |
|---|---|---|---|---|---|---|---|
 Pittsburgh Home Stats |
7-3 | 55.50 | 35.50 | 20.00 | 5 | 5 | |
 Central Michigan Away Stats |
1-9 | 51.00 | 17.30 | 33.70 | 5 | 5 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O50.5 = Games Over 50.5 Points
- U50.5 = Games Under 50.5 Points
Latest regular season and playoff games stats.
Central Michigan Chippewas Stats
Pittsburgh Stats
- 4 wins and 6 defeats in the last 10 games
- 1 win and 9 defeats in the last 10 games on the road
- +21.5 Betting Line: Have covered the spread in 8 of the last 10 games
- +21.5 Betting Line on the Road: Have covered the spread in 7 of the last 10 games on the road
- -21.5 Betting Line: Have covered the spread in 2 of the last 10 games
- -21.5 Betting Line at Home: Have covered the spread in 4 of the last 10 home games
- Game Totals: An average of 47.40 pts in the previous 10 games
- Game Totals on the Road: An average of 51.00 pts in the previous 10 games on the road
- Over 50.5: Covered in 4 of the previous 10 games
- Over 50.5 on the Road: Covered in 5 of the previous 10 games on the road
- Team Totals: Have scored an average of 19.60 pts and allowed 27.80 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 17.30 pts and allowed 33.70 pts in the last 10 games on the road
- Game Totals: An average of 57.10 pts in the previous 10 games
- Game Totals at Home: An average of 55.50 pts in the previous 10 home games
- Over 50.5: Covered in 6 of the previous 10 games
- Over 50.5 at Home: Covered in 5 of the previous 10 home games
- Team Totals: Have scored an average of 29.50 pts and allowed 27.60 pts in the last 10 games
- Team Totals at Home: Have scored an average of 35.50 pts and allowed 20.00 pts in the last 10 home games
| Atlantic Coast | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Virginia
|
10 | 2 | 398 | 240 | 158 | 6-1 | 4-1 | 2W |
Miami
|
10 | 2 | 409 | 166 | 243 | 7-1 | 3-1 | 4W |
Georgia Tech
|
9 | 3 | 397 | 300 | 97 | 5-2 | 4-1 | 2L |
|
Pittsburgh
|
8 | 4 | 421 | 299 | 122 | 4-3 | 4-1 | 1L |
SMU
|
8 | 4 | 395 | 248 | 147 | 5-1 | 3-3 | 1L |
Louisville
|
8 | 4 | 362 | 253 | 109 | 5-3 | 3-1 | 1W |
Wake Forest
|
8 | 4 | 322 | 258 | 64 | 5-2 | 3-2 | 1L |
Duke
|
7 | 5 | 415 | 353 | 62 | 3-3 | 4-2 | 2W |
NC State
|
7 | 5 | 362 | 346 | 16 | 6-1 | 1-4 | 2W |
Clemson
|
7 | 5 | 344 | 245 | 99 | 3-4 | 4-1 | 4W |
California
|
7 | 5 | 298 | 318 | -20 | 4-2 | 3-3 | 1W |
Florida State
|
5 | 7 | 396 | 264 | 132 | 5-2 | 0-5 | 2L |
Stanford
|
4 | 8 | 226 | 350 | -124 | 4-2 | 0-6 | 1L |
North Carolina
|
4 | 8 | 231 | 294 | -63 | 2-4 | 2-4 | 3L |
Virginia Tech
|
3 | 9 | 257 | 362 | -105 | 2-5 | 1-4 | 4L |
Syracuse
|
3 | 9 | 242 | 419 | -177 | 2-4 | 1-5 | 8L |
Boston College
|
2 | 10 | 305 | 393 | -88 | 1-6 | 1-4 | 1W |
| Mid-American | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Western Michigan
|
8 | 4 | 284 | 224 | 60 | 5-1 | 3-3 | 4W |
Ohio
|
8 | 4 | 344 | 275 | 69 | 6-0 | 2-4 | 2W |
Toledo
|
8 | 4 | 379 | 146 | 233 | 6-0 | 2-4 | 4W |
Miami (OH)
|
7 | 5 | 313 | 263 | 50 | 4-2 | 3-3 | 2W |
|
Central Michigan
|
7 | 5 | 286 | 272 | 14 | 4-1 | 3-4 | 1L |
Akron
|
5 | 7 | 267 | 329 | -62 | 3-3 | 2-4 | 1W |
Buffalo
|
5 | 7 | 288 | 282 | 6 | 2-5 | 3-2 | 3L |
Kent State
|
5 | 7 | 255 | 403 | -148 | 3-2 | 2-5 | 1W |
Ball State
|
4 | 8 | 190 | 358 | -168 | 4-1 | 0-7 | 3L |
Eastern Michigan
|
4 | 8 | 289 | 357 | -68 | 3-3 | 1-5 | 1L |
Bowling Green
|
4 | 8 | 246 | 291 | -45 | 3-3 | 1-5 | 1W |
Northern Illinois
|
3 | 9 | 205 | 292 | -87 | 2-4 | 1-5 | 2L |
UMass
|
0 | 12 | 133 | 463 | -330 | 0-6 | 0-6 | 12L |
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