Duke vs Virginia Prediction, Picks & Odds | 06 Dec 2025
College Football Betting Preview: Duke vs Virginia
Duke face Virginia in the ACC Championship Game at Scott Stadium, with kickoff scheduled for 20:00 on Saturday, December 6.
Let’s back Duke who have been given a generous +3.5 on the spread. We think -102 can be taken with confidence that they cover the line against Virginia.
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Duke Blue Devils claimed a home victory in their previous game. A 49-32 triumph against Wake Forest at Wallace Wade Stadium made it back-to-back wins.
Virginia Cavaliers made it back-to-back wins in their last game. Landing a 27-7 home victory against Virginia Tech Hokies at Scott Stadium.
Head-to-Head Statistics
Virginia have beaten Duke in the last two matchups. They won 30-27 at Scott Stadium and triumphed 34-17 at Wallace Wade Stadium. It’s been five Virginia wins in the past 6 games between these teams.
Quarterbacks
Darian Mensah
Chandler Morris
Duke vs Virginia Prediction & Picks
Get the edge with our best Duke vs Virginia tips: a key match prediction, correct score recommendation, top player prop bets and a ready-made bet builder.
Game Prediction
Duke are capable of staying close to the favorites in this college football matchup, so we’ll take a chance and wager the underdogs against the spread. There’s an attractive +3.5 available which is priced at -102.
Knowing which players are injured gives us a valuable edge when making college football predictions. After reviewing the form guide, we turn to the latest stats to shape our picks.
Key Duke vs Virginia stats:
Duke +3.5 Probability
The top sportsbooks are estimating that there is a 50.5% likelihood of this pick winning. Taking all factors into consideration, our analysts think there’s a stronger chance of success and estimate the probability to be closer to 60%. The bet can be recommended for this precise reason.
Want bigger odds when it comes to your point spread wager? Never fear, you are able to head to the sportsbooks and move the betting line until you’re happy with the price.
Don’t miss out. Check our expert guide for the most rewarding betting offers, including top free bets and bonuses.
Player Prop Picks
You can place a bet on Andrel Anthony (Duke) to score a TD at +165. He looks like an attractive wager to take it to the house and we recommend backing this Anytime Touchdown Scorer selection.
J'Mari Taylor (Virginia) is priced at -114 to go over 89.5 rushing yards. The line for him on the Overs is highly appealing, with Player Rushing Yards bettors able to get plenty of juice.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
We’ve loaded up a same game parlay with the combined picks of Duke +3.5, Under 57.5 and Andrel Anthony (Duke) scoring a touchdown.
A same game parlay is a fantastic option for bettors who want to focus their wagering on a single football game. You can predict different outcomes and see their odds combined before going ahead and placing this tailored bet.
Correct Score Prediction
27
-
24
Virginia
There’s every chance that this is going to be a close matchup and we’ll have a play on Duke achieving a 27-24 winning scoreline. Hopefully this can go close.
Duke vs Virginia Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
Virginia are -179 favorites and that means a 64% chance of winning this college game according to the Moneyline betting odds with the sportsbooks. If you’re looking for an alternative angle, Duke are trading at +152.
There is a spread of 3.5 and total points has a line of 58.5. A wager on the Totals allows football bettors to use the latest data to good effect. If you’re going for Under 58.5, this outcome can be backed at -110.
The best betting apps provide tons of game lines and team props for nearly every college football matchup. Take a few moments to browse all the markets so you can place a bet that matches your insight.
The First Touchdown Scorer favorite is J'Mari Taylor at +340. Similar odds can be found if you’re interested in this player to register the final TD.
Touchdown
Receiving Yards
Rushing Yards
Passing Yards
For those looking to enjoy a thrilling in-game wager, then college football micro betting could be up your street. You are now able to wager on what will happen on the next snap by staking your money on the Next Play Result.
Latest regular season and playoff games stats.
Duke Blue Devils Stats
Virginia Cavaliers Stats
- 6 wins and 4 defeats in the last 10 games
- 6 wins and 4 defeats in the last 10 games on the road
- +3.5 Betting Line: Have covered the spread in 7 of the last 10 games
- +3.5 Betting Line on the Road: Have covered the spread in 7 of the last 10 games on the road
- -3.5 Betting Line: Have covered the spread in 6 of the last 10 games
- -3.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games
- Game Totals: An average of 64.20 pts in the previous 10 games
- Game Totals on the Road: An average of 63.10 pts in the previous 10 games on the road
- Over 57.5: Covered in 6 of the previous 10 games
- Over 57.5 on the Road: Covered in 6 of the previous 10 games on the road
- Team Totals: Have scored an average of 35.10 pts and allowed 29.10 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 32.50 pts and allowed 30.60 pts in the last 10 games on the road
- Game Totals: An average of 51.70 pts in the previous 10 games
- Game Totals at Home: An average of 51.80 pts in the previous 10 home games
- Over 57.5: Covered in 3 of the previous 10 games
- Over 57.5 at Home: Covered in 3 of the previous 10 home games
- Team Totals: Have scored an average of 31.90 pts and allowed 19.80 pts in the last 10 games
- Team Totals at Home: Have scored an average of 29.60 pts and allowed 22.20 pts in the last 10 home games
| Atlantic Coast | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Miami
|
10 | 2 | 409 | 166 | 243 | 7-1 | 3-1 | 4W |
|
Virginia
|
10 | 3 | 418 | 267 | 151 | 6-2 | 4-1 | 1L |
Georgia Tech
|
9 | 3 | 397 | 300 | 97 | 5-2 | 4-1 | 2L |
Pittsburgh
|
8 | 4 | 421 | 299 | 122 | 4-3 | 4-1 | 1L |
SMU
|
8 | 4 | 395 | 248 | 147 | 5-1 | 3-3 | 1L |
Louisville
|
8 | 4 | 362 | 253 | 109 | 5-3 | 3-1 | 1W |
Wake Forest
|
8 | 4 | 322 | 258 | 64 | 5-2 | 3-2 | 1L |
|
Duke
|
8 | 5 | 442 | 373 | 69 | 3-3 | 5-2 | 3W |
NC State
|
7 | 5 | 362 | 346 | 16 | 6-1 | 1-4 | 2W |
California
|
7 | 5 | 298 | 318 | -20 | 4-2 | 3-3 | 1W |
Clemson
|
7 | 5 | 344 | 245 | 99 | 3-4 | 4-1 | 4W |
Florida State
|
5 | 7 | 396 | 264 | 132 | 5-2 | 0-5 | 2L |
Stanford
|
4 | 8 | 226 | 350 | -124 | 4-2 | 0-6 | 1L |
North Carolina
|
4 | 8 | 231 | 294 | -63 | 2-4 | 2-4 | 3L |
Virginia Tech
|
3 | 9 | 257 | 362 | -105 | 2-5 | 1-4 | 4L |
Syracuse
|
3 | 9 | 242 | 419 | -177 | 2-4 | 1-5 | 8L |
Boston College
|
2 | 10 | 305 | 393 | -88 | 1-6 | 1-4 | 1W |
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