Indiana vs Iowa Prediction, Picks & Odds | 27 Sep 2025
College Football Betting Preview: Indiana vs Iowa
Indiana face Iowa in this NCAAF Week 5 matchup at Kinnick Stadium, with kickoff scheduled for 15:30 on Saturday, September 27. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.
There’s a good opportunity to back Iowa against the spread considering the underdogs should perform well against Indiana. Snap up the -100 when it comes to them covering the +7.5.
Rolling with our spread angle? Snag our exclusive BetMGM promo code and read the in-depth review of the sportsbook before you commit to your play.
Indiana Hoosiers beat Illinois Fighting Illini in their previous game, making it four straight victories. It was a 63-10 home win at Memorial Stadium.
Iowa Hawkeyes won last time out by a 38-28 scoreline. On the road against Rutgers Scarlet Knights at SHI Stadium, they made it back-to-back wins.
Head-to-Head Statistics
It was Iowa who came out on top when they last played Indiana. At Kinnick Stadium, a 34-6 win was recorded.
Quarterbacks
Fernando Mendoza
Mark Gronowski
Indiana vs Iowa Prediction & Picks
The Indiana vs Iowa betting tips feature sharp analysis across major markets, including a key match prediction, player prop bets, correct score guidance and a ready-made bet builder.
Game Prediction
We’re happy to get with Iowa against the spread in this college football matchup. -100 is available that they are able to cover +7.5 and that looks more than reasonable.
Team news and current form always play a key role in shaping our expert CFB predictions. We also dig into the latest stats and trends to help deliver the most accurate picks possible.
Key Indiana vs Iowa stats:
Iowa +7.5 Probability
The top betting apps make it a 50% chance that our pick is settled as a winner. Based on our in-depth research, we calculate the actual probability to be closer to 60%. That means we’re regarding it as a value bet.
If you want to back Iowa without taking them on the point spread, there’s the alternative to go for a Winning Margin wager instead. There are lots of different options here.
Before placing your next bet, explore our complete guide to the best betting offers, promotions and welcome bonuses today.
Player Prop Picks
The odds for Fernando Mendoza (Indiana) to end with fewer than 250.5 passing yards are -114. It’s reasonable to expect he may fall short, making the QB Passing Yards line appealing.
E.J. Williams Jr. (Iowa) can be backed at -114 to record fewer than 29.5 receiving yards. We’re confident he’ll fall short of the Player Receiving Yards line, as the total looks too high.
Same Game Parlay Picks
Try out our same game parlay pick which starts with Iowa +7.5. We’ve also gone for Over 48.5 points and Fernando Mendoza (Indiana) to have Under 250.5 passing yards.
A same game parlay is a fantastic option for bettors who want to focus their wagering on a single football game. You can predict different outcomes and see their odds combined before going ahead and placing this tailored bet.
Correct Score Prediction
28
-
24
Iowa
There might not be too much between these teams, with our correct score pick being a 28-24 victory for the Hoosiers. There are huge odds available when it comes to this prediction.
Indiana vs Iowa Odds
The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.
Indiana have the shortest price to win this college game, with the sportsbooks giving them a 77% probability due to their -333 Moneyline betting odds. For those wanting to back Iowa, you will find +265 about the underdogs.
There is a spread of 9.5 and total points has a line of 47.5. Football fans love the chance to get an alternative angle by going for a Total wager. Those expecting a low total can back Under 47.5 at -110.
The good news is that you can access a huge selection of team props and game lines for most college football matchups. The top sportsbooks have a massive range of pre-game and in-game wagering options.
The Anytime Touchdown betting indicates that Elijah Sarratt has odds of %anytime_odds%. He is available at %first_odds% to score the first TD which makes him favorite.
Touchdown
Receiving Yards
Rushing Yards
Passing Yards
You don’t have to wait for the final outcome when it comes to college football micro betting. Instead, there’s the opportunity to wager on live lines which tend to be settled in a shorter space of time and the in-game odds are always changing.
Iowa Rolling at Home
Iowa have rattled off seven straight wins at Kinnick Stadium. They have eight wins and two losses in the last 10 games at home, averaging 31.30 points scored and 13.10 points allowed.
Indiana have three wins and seven losses in the last 10 games on the road, averaging 28.60 points scored and 32.40 points allowed.
Iowa beat Indiana 34-6 when they last met at Kinnick Stadium.
| Last 10 Games | W-L | P | PF | PA | O48.5 | U48.5 | |
|---|---|---|---|---|---|---|---|
 Iowa Home Stats |
8-2 | 44.40 | 31.30 | 13.10 | 5 | 5 | |
 Indiana Away Stats |
3-7 | 61.00 | 28.60 | 32.40 | 9 | 1 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O48.5 = Games Over 48.5 Points
- U48.5 = Games Under 48.5 Points
Latest regular season and playoff games stats.
Indiana Hoosiers Stats
Iowa Hawkeyes Stats
- 8 wins and 2 defeats in the last 10 games
- 3 wins and 7 defeats in the last 10 games on the road
- -7.5 Betting Line: Have covered the spread in 7 of the last 10 games
- -7.5 Betting Line on the Road: Have covered the spread in 3 of the last 10 games on the road
- +7.5 Betting Line: Have covered the spread in the last 10 games
- +7.5 Betting Line at Home: Have covered the spread in 9 of the last 10 home games
- Game Totals: An average of 55.50 pts in the previous 10 games
- Game Totals on the Road: An average of 61.00 pts in the previous 10 games on the road
- Over 48.5: Covered in 6 of the previous 10 games
- Over 48.5 on the Road: Covered in 9 of the previous 10 games on the road
- Team Totals: Have scored an average of 41.50 pts and allowed 14.00 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 28.60 pts and allowed 32.40 pts in the last 10 games on the road
- Game Totals: An average of 44.90 pts in the previous 10 games
- Game Totals at Home: An average of 44.40 pts in the previous 10 home games
- Over 48.5: Covered in 5 of the previous 10 games
- Over 48.5 at Home: Covered in 5 of the previous 10 home games
- Team Totals: Have scored an average of 29.70 pts and allowed 15.20 pts in the last 10 games
- Team Totals at Home: Have scored an average of 31.30 pts and allowed 13.10 pts in the last 10 home games
| Big Ten | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
|
Indiana
|
12 | 0 | 532 | 131 | 401 | 7-0 | 5-0 | 12W |
Ohio State
|
12 | 0 | 444 | 93 | 351 | 7-0 | 5-0 | 12W |
Oregon
|
11 | 1 | 458 | 178 | 280 | 6-1 | 5-0 | 6W |
Michigan
|
9 | 3 | 331 | 224 | 107 | 5-1 | 4-2 | 1L |
USC
|
9 | 3 | 438 | 269 | 169 | 7-0 | 2-3 | 1W |
|
Iowa
|
8 | 4 | 347 | 182 | 165 | 5-2 | 3-2 | 2W |
Illinois
|
8 | 4 | 352 | 279 | 73 | 6-1 | 2-3 | 1W |
Washington
|
8 | 4 | 405 | 233 | 172 | 5-2 | 3-2 | 1L |
Minnesota
|
7 | 5 | 279 | 281 | -2 | 7-0 | 0-5 | 1W |
Nebraska
|
7 | 5 | 351 | 276 | 75 | 4-3 | 3-2 | 2L |
Northwestern
|
6 | 6 | 270 | 251 | 19 | 5-2 | 1-4 | 1L |
Penn State
|
6 | 6 | 381 | 257 | 124 | 4-3 | 2-3 | 3W |
Rutgers
|
5 | 7 | 344 | 382 | -38 | 4-3 | 1-4 | 2L |
Wisconsin
|
4 | 8 | 154 | 259 | -105 | 4-3 | 0-5 | 1L |
Maryland
|
4 | 8 | 282 | 318 | -36 | 3-4 | 1-4 | 8L |
Michigan State
|
4 | 8 | 295 | 359 | -64 | 4-3 | 0-5 | 1W |
UCLA
|
3 | 9 | 218 | 401 | -183 | 2-4 | 1-5 | 5L |
Purdue
|
2 | 10 | 225 | 382 | -157 | 2-5 | 0-5 | 10L |
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