Indiana vs Ohio State Prediction, Picks & Odds | 06 Dec 2025
College Football Betting Preview: Indiana vs Ohio State
Indiana go up against Ohio State in the Big Ten Championship Game at Ohio Stadium, with kickoff scheduled for 20:00 on Saturday, December 6.
Ohio State should be able to cover the -4.5 betting line against Indiana. We’re confident of a strong showing and a wager on the spread is the best play at odds of -105.
Taking our side against the spread? Secure the new BetMGM promo code and see how the site rates in our expert sportsbook review before placing your wager.
Indiana Hoosiers have also won twelve on the spin, triumphing 56-3 in their previous game. This was on the road against Purdue Boilermakers at Ross-Ade Stadium.
Ohio State Buckeyes got a twelfth straight win in their last game. It was a 27-9 road triumph at Michigan Stadium when meeting Michigan Wolverines.
Head-to-Head Statistics
The last matchup between Ohio State and Indiana saw the former win. It was a 38-15 scoreline at Ohio Stadium. Ohio State have a 100% win record when it comes to the previous 6 H2H meetings.
Quarterbacks
Fernando Mendoza
Julian Sayin
Indiana vs Ohio State Prediction & Picks
Our Indiana vs Ohio State betting tips provide expert coverage of all major angles, including our main match prediction, top player prop picks, correct score recommendation and best bet builder insights.
Game Prediction
Back the moneyline favorites with a -4.5 spread in the college football matchup. This is a good number and we're confident Ohio State can cover this appealing line at odds of -105.
To deliver the best possible college football picks, we start by locking in the team news and taking time to review the latest form. There’s also no shortage of data to crunch from the most up-to-date stats available.
Key Indiana vs Ohio State stats:
Ohio State -4.5 Probability
The top betting apps make it a 51.3% chance that our pick is settled as a winner. However, our cappers have this number between 55-60% based on their in-depth research. It's why we think it’s worth placing this college wager.
If you’re in pursuit of bigger odds, then a Bet Builder could be a way forward. Take Ohio State to cover the line with additional selections until you’re satisfied with the price.
Before placing your bets, take advantage of our guide packed with up-to-date free bets and the latest bonus offers.
Player Prop Picks
Jeremiah Smith (Ohio State) can be backed at -145 to reach the end zone. The Anytime Touchdown Scorer odds are appealing from all angles and we’re willing to take a chance on him.
Fernando Mendoza (Indiana) is priced at -114 to rack up over 210.5 passing yards. He looks capable of covering the line and that leads us to taking this QB Passing Yards bet.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
Take a same game parlay that incorporates Ohio State to cover the -4.5 spread along with Over 47.5 points. Add in Jeremiah Smith (Ohio State) as an anytime touchdown scorer.
There are many options when you place a same game parlay. You can go through the football lines and identify your favorite outcomes before combining the odds on the bet slip. Personalised betting doesn’t come any better.
Correct Score Prediction
23
-
31
Ohio State
A 31-23 win for the Buckeyes is clearly a risky bet although this could be an exciting correct score option where there’s the chance to enjoy a massive potential return.
Indiana vs Ohio State Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
For this college game, the sportsbooks’ Moneyline betting odds mean Ohio State are -185 favorites to win and that means a 65% chance of landing a victory. If you’re looking for an alternative angle, Indiana are trading at +154.
The current spread is 4.5 and the total points line is 46.5. Football fans love the chance to get an alternative angle by going for a Total wager. There’s the chance to back Under 46.5 at -110.
The top sportsbooks cover every college football matchup with a great mix of game lines and team props. Whether you prefer to bet before kickoff or during the action, make sure to explore all available options.
Jeremiah Smith is the market leader at +500 to be the First TD Scorer. Should you think he will score the final touchdown, then a similar price can be found.
Touchdown
Receiving Yards
Rushing Yards
Passing Yards
An increasing number of bettors are now enjoying micro betting on college football and it’s something which is available on an in-game basis. Wait for the action to start and then wager on something specific to happen.
Latest regular season and playoff games stats.
Indiana Hoosiers Stats
Ohio State Buckeyes Stats
- 10 wins and 0 defeats in the last 10 games
- 8 wins and 2 defeats in the last 10 games on the road
- +4.5 Betting Line: Have covered the spread in the last 10 games
- +4.5 Betting Line on the Road: Have covered the spread in 8 of the last 10 games on the road
- -4.5 Betting Line: Have covered the spread in the last 10 games
- -4.5 Betting Line at Home: Have covered the spread in 9 of the last 10 home games
- Game Totals: An average of 55.70 pts in the previous 10 games
- Game Totals on the Road: An average of 53.40 pts in the previous 10 games on the road
- Over 47.5: Covered in 8 of the previous 10 games
- Over 47.5 on the Road: Covered in 8 of the previous 10 games on the road
- Team Totals: Have scored an average of 44.90 pts and allowed 10.80 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 35.00 pts and allowed 18.40 pts in the last 10 games on the road
- Game Totals: An average of 44.60 pts in the previous 10 games
- Game Totals at Home: An average of 47.80 pts in the previous 10 home games
- Over 47.5: Covered in 4 of the previous 10 games
- Over 47.5 at Home: Covered in 6 of the previous 10 home games
- Team Totals: Have scored an average of 36.00 pts and allowed 8.60 pts in the last 10 games
- Team Totals at Home: Have scored an average of 38.10 pts and allowed 9.70 pts in the last 10 home games
| Big Ten | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
|
Indiana
|
13 | 0 | 545 | 141 | 404 | 7-0 | 6-0 | 13W |
|
Ohio State
|
12 | 1 | 454 | 106 | 348 | 7-1 | 5-0 | 1L |
Oregon
|
11 | 1 | 458 | 178 | 280 | 6-1 | 5-0 | 6W |
Michigan
|
9 | 3 | 331 | 224 | 107 | 5-1 | 4-2 | 1L |
USC
|
9 | 3 | 438 | 269 | 169 | 7-0 | 2-3 | 1W |
Iowa
|
8 | 4 | 347 | 182 | 165 | 5-2 | 3-2 | 2W |
Illinois
|
8 | 4 | 352 | 279 | 73 | 6-1 | 2-3 | 1W |
Washington
|
8 | 4 | 405 | 233 | 172 | 5-2 | 3-2 | 1L |
Minnesota
|
7 | 5 | 279 | 281 | -2 | 7-0 | 0-5 | 1W |
Nebraska
|
7 | 5 | 351 | 276 | 75 | 4-3 | 3-2 | 2L |
Northwestern
|
6 | 6 | 270 | 251 | 19 | 5-2 | 1-4 | 1L |
Penn State
|
6 | 6 | 381 | 257 | 124 | 4-3 | 2-3 | 3W |
Rutgers
|
5 | 7 | 344 | 382 | -38 | 4-3 | 1-4 | 2L |
Wisconsin
|
4 | 8 | 154 | 259 | -105 | 4-3 | 0-5 | 1L |
Maryland
|
4 | 8 | 282 | 318 | -36 | 3-4 | 1-4 | 8L |
Michigan State
|
4 | 8 | 295 | 359 | -64 | 4-3 | 0-5 | 1W |
UCLA
|
3 | 9 | 218 | 401 | -183 | 2-4 | 1-5 | 5L |
Purdue
|
2 | 10 | 225 | 382 | -157 | 2-5 | 0-5 | 10L |
Metaloglobus
Csikszereda
Predictions
11:00 - Wed 04 Feb
SuperLiga
UTA Arad
CFR Cluj
Predictions
11:30 - Wed 04 Feb
Super League Greece
Asteras Tripolis
Olympiacos
Predictions
12:00 - Wed 04 Feb
EuroCup
Besiktas
Turk Telekom
Predictions
12:00 - Wed 04 Feb
EuroCup
Lietkabelis
Panionios
Predictions
13:00 - Wed 04 Feb
EuroCup
Hapoel Jerusalem
Cluj-Napoca
Predictions