Louisiana vs South Alabama Prediction, Picks & Odds | 01 Nov 2025

College Football Betting Preview: Louisiana vs South Alabama

Louisiana go up against South Alabama in this NCAAF matchup at Hancock Whitney Stadium, with kickoff scheduled for 14:30 on Saturday, November 1. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.

Don’t miss the opportunity to side with South Alabama on the spread at -4.5. On the face of it, this seems a generous line and odds of -102 can be backed in their clash against Louisiana.

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Louisiana Ragin Cajuns have suffered a defeat in their previous four road games including a recent 35-23 loss. This occurred at Veterans Memorial Stadium against Troy State Trojans.

South Alabama Jaguars have lost their last three home games. Most recently, they won on the road when beating Georgia State Panthers 38-31 at Center Parc Stadium.

Head-to-Head Statistics

The last head-to-head saw South Alabama claim a 24-22 win over Louisiana at Cajun Field. The past 6 games between the teams have seen Louisiana win four times.

Louisiana vs South Alabama Prediction & Picks

We’ve got your Louisiana vs South Alabama bets covered, including our expert match prediction, correct score recommendation and a hand-picked bet builder tailored for value.

Game Prediction

It’s time to go for South Alabama against the spread, especially with an attractive -4.5 line at -102. Our pick is that the favorites can achieve a comfortable win in this college football battle.

Sportsgambler.com brings strong college football expertise, built on knowing the team news as soon as it’s confirmed. Recent form plays a big part in our CFB picks and we always back it up with the most relevant stats.

Key Louisiana vs South Alabama stats:

• The +4.5 line hasn’t been covered by Louisiana in 4 of their last 5 games on the road.
• The +4.5 line hasn’t been covered by Louisiana in 6 of their last 10 games.
• The +4.5 line hasn’t been covered by Louisiana in 3 consecutive games.

South Alabama -4.5 Probability

Based on the odds from the top sportsbooks, our pick has a 50.5% chance of winning. However, our research has found that the actual probability is closer to 60%. This is why we can recommend this college bet.

If you want bigger odds, then you can move the line by selling points. Choose how many points to sell until you are happy with the juice available.

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Our Game Prediction

South Alabama -4.5 @ -102 Bet Now

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Correct Score Prediction

Louisiana 23 - 34 South Alabama

There are a range of correct score lines to choose from and we’re taking a chance on South Alabama to claim a 34-23 win. There’s a huge return if we get this right.

Louisiana vs South Alabama Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Sportsbooks’ favorites South Alabama are regarded as likeliest victors for this college game and the -172 about them triumphing means a 63% chance based on their current Moneyline betting odds. Louisiana are regarded as a long shot to win and you can currently back them at +144.

3.5 is where the spread lies, with total points being 52.5 right now. Having a bet on the Totals is one of the most popular football wagers. There’s the chance to back Under 52.5 at -105.

You can find a nice selection of game lines and team props for every college football game, with the top betting apps creating many different options. Check out the pre-game and in-game selections before placing your bets.

Moneyline

Louisiana

+144

South Alabama

-172

Point Spread

Louisiana +3.5

-105

South Alabama -3.5

-115

Total Points

Under 52.5

-105

Over 52.5

-115

Should you be more interested in a specific individual who is competing, check out the gambling sites’ prop bets where you can pick out player and quarterback lines that focus on performance rather than the game result.

It’s good to consider all wagering options when it comes to college football and micro betting can be an exciting way to get involved in the action. When everything goes in-game, consider whether a player will make or miss a field goal.

South Alabama Have Dropped Last Three Home Games

South Alabama have been beaten three times in a row at Hancock Whitney Stadium. They have a 4-6 record in their last 10 home games, averaging 36.70 points scored and 27.40 points allowed.

Louisiana have lost five straight on the road. They are 5-5 in their last 10 games on the road, putting up 23.90 points on average and giving up 29.40.

In their last matchup at Hancock Whitney Stadium, Louisiana came out on top 33-20 against South Alabama.

Last 10 Games		W-L	P	PF	PA	O52.5	U52.5
South Alabama Home Stats		4-6	64.10	36.70	27.40	8	2
Louisiana Away Stats		5-5	53.30	23.90	29.40	6	4

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O52.5 = Games Over 52.5 Points
• U52.5 = Games Under 52.5 Points

Latest regular season and playoff games stats.

Louisiana Ragin Cajuns Stats

South Alabama Jaguars Stats

Moneyline

• 2 wins and 8 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 4 wins and 6 defeats in the last 10 home games

Point Spread

• +4.5 Betting Line: Have covered the spread in 4 of the last 10 games
• +4.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• -4.5 Betting Line: Have covered the spread in 3 of the last 10 games
• -4.5 Betting Line at Home: Have covered the spread in 4 of the last 10 home games

Total Points

• Game Totals: An average of 50.10 pts in the previous 10 games
• Game Totals on the Road: An average of 53.30 pts in the previous 10 games on the road
• Over 52.5: Covered in 4 of the previous 10 games
• Over 52.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 19.40 pts and allowed 30.70 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 23.90 pts and allowed 29.40 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 57.40 pts in the previous 10 games
• Game Totals at Home: An average of 64.10 pts in the previous 10 home games
• Over 52.5: Covered in 8 of the previous 10 games
• Over 52.5 at Home: Covered in 8 of the previous 10 home games
• Team Totals: Have scored an average of 27.00 pts and allowed 30.40 pts in the last 10 games
• Team Totals at Home: Have scored an average of 36.70 pts and allowed 27.40 pts in the last 10 home games

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