LSU Tigers
American Football NCAAF Memorial Stadium Sat 30 Aug 19:30
Clemson Tigers
  1. Prediction
  2. SGP Picks
  3. Odds
  4. Player Props
  5. Stats
  6. Standings

College Football Betting Preview: LSU vs Clemson

LSU meet Clemson in this NCAAF Week 1 matchup at Memorial Stadium, with kickoff scheduled for 19:30 on Saturday 30 August. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.

The Value Lies With Clemson

Clemson should be taken against the spread at -3.5 with our prediction being for the favorites to achieve a comfortable margin of victory in their meeting with LSU. Back them at the odds of -118 that are available.

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LSU Beat Clemson in their Last Matchup

LSU Tigers won their most recent outing, beating the Baylor Bears 44–31 in the Texas Bowl at NRG Stadium.

Clemson Tigers lost their last game, falling 38–24 on the road to the Texas Longhorns in the College Football Playoff First Round at DKR–Texas Memorial Stadium.

Head-to-Head Statistics

The last head-to-head saw LSU claim a 42-25 win over Clemson at Caesars Superdome.

Quarterbacks

LSU vs Clemson Prediction & Picks

Get the edge with our best LSU vs Clemson tips: a key match prediction, correct score recommendation, top player prop bets and a ready-made bet builder.

Game Prediction

Bet on Clemson against the spread, with an attractive line of -3.5 that the favorites get the job done. There are odds of -118 that are currently on offer for this college football matchup.

We closely track recent form and look for patterns that may impact the outcome. The same goes for injuries to key players. When combined with the most relevant stats, this gives us a strong foundation for accurate CFB picks.

Key LSU vs Clemson stats:

  • The -3.5 line has been covered by Clemson in 8 of their last 10 games at home.
  • The -3.5 line has been covered by Clemson in 15 of their last 20 games at home.
  • The +3.5 line hasn’t been covered by LSU in 3 of their last 5 games on the road.
  • The +3.5 line hasn’t been covered by LSU in 11 of their last 20 games on the road.
  • The +3.5 line hasn’t been covered by LSU in 2 consecutive games on the road.

Clemson -3.5 Probability

According to the best betting apps, there’s a 54.1% chance that our pick is settled as a winner. After careful examination, our cappers have this probability close to 60%. This is why we can recommend this college wager.

Looking for Bigger Odds?

As a wagering alternative, you can choose to buy or sell points when it comes to your spread pick. Buy if you want a safer bet and sell to get more juice from the line.

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Best Bet

Clemson -3.5 @ -118 Bet Now BetMGM logo
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Published 02:26, 29 August 2025

Player Prop Picks

Top Pick: Garrett Nussmeier Under 290.5 Passing Yards -114 BetMGM logo

You can back Garrett Nussmeier (LSU) at -114 to record fewer than 290.5 passing yards. He could struggle to reach the QB Passing Yards line, making this prop bet highly appealing.

Latest Garrett Nussmeier Player Prop Odds

Caden Durham Under 62.5 Rushing Yards --100 BetMGM logo

You can place a bet on Caden Durham (Clemson) at --100 to have less than 62.5 rushing yards. He may fall short of the Player Rushing Yards line, making this prop bet a strong pick.

Latest Caden Durham Player Prop Odds

Same Game Parlay Picks

Spread Clemson -3.5
Totals Under 57.5
Passing Yards Garrett Nussmeier Under 290.5

We’ve got a same game parlay with three options: Clemson -3.5, Under 57.5 points and Garrett Nussmeier (LSU) to go Under 290.5 passing yards.

There are many options when you place a same game parlay. You can go through the football lines and identify your favorite outcomes before combining the odds on the bet slip. Personalised betting doesn’t come any better.

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Correct Score Prediction

LSU LSU logo 23 - 31 Clemson logo Clemson

There’s the chance to back Clemson in lots of different ways and this includes predicting the correct winning score. We’ll go for a 31-23 triumph in their favor.

LSU vs Clemson Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Clemson Favorites to Win According to the Books

The sportsbooks have Clemson at -192 when it comes to the Moneyline betting, implying the market leaders are 66% likely to win this college game according to the latest odds. LSU are the underdogs at +158 and they’re regarded as least likely to win.

The current spread is 4.5 and total points is 55.5. A Total wager is always available and can often provide value selections. If you’re going for Under 55.5, this outcome can be backed at -115.

The top sportsbooks cover every college football matchup with a great mix of game lines and team props. Whether you prefer to bet before kickoff or during the action, make sure to explore all available options.

Adam Randall Favorite to Be First TD Scorer

Adam Randall is the First Touchdown Scorer favorite at +550. Alternatively, there’s the opportunity to simply back him to score a TD anytime at -149.

Touchdown

Adam Randall (Clemson)
First TD
+550
Anytime TD
-149
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Antonio Williams (Clemson)
First TD
+800
Anytime TD
-100
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Cade Klubnik (Clemson)
First TD
+950
Anytime TD
+105
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Receiving Yards

Antonio Williams (Clemson)
Over 58.5
-112
Under 58.5
-112
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Bryant Wesco Jr. (Clemson)
Over 58.5
-112
Under 58.5
-112
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Rushing Yards

Passing Yards

Micro Betting

Instead of focusing on the overall outcome, some bettors prefer to look at the college football micro betting lines. As the name suggests, it means placing short-term in-game wagers and this might include the Next Play or Next Drive Result.

Best Betting Offers
Memorial Stadium
Memorial Stadium

Clemson Have Won Eight of Their Last Ten Home Games

Clemson have a 8-2 record in their last 10 home games, posting 40.30 points per contest while yielding 22.80.

LSU have five wins and five losses in the last 10 road games, posting 36.30 points per matchup while yielding 31.00.

Last 10 Games W-L P PF PA O57.5 U57.5
Clemson logo Clemson Home Stats 8-2 63.10 40.30 22.80 5 5
LSU logo LSU Away Stats 5-5 67.30 36.30 31.00 7 3
  • W-L = Wins-Losses
  • P = Avg. Points
  • PF = Avg. Points For
  • PA = Avg. Points Against
  • O57.5 = Games Over 57.5 Points
  • U57.5 = Games Under 57.5 Points
Team Stats

Latest regular season and playoff games stats.

LSU Tigers logo LSU Tigers Stats
Clemson Tigers logo Clemson Tigers Stats
Moneyline
  • 7 wins and 3 defeats in the last 10 games
  • 5 wins and 5 defeats in the last 10 games on the road
Moneyline
  • 7 wins and 3 defeats in the last 10 games
  • 8 wins and 2 defeats in the last 10 home games
Point Spread
Point Spread
Total Points
Total Points

NCAAF Standings Select Season

Atlantic Coast W L PF PA N. Pts Home Away Strk
Georgia Tech 6 0 220 126 94 4-0 2-0 6W
Miami 5 0 175 68 107 4-0 1-0 5W
Virginia 5 1 258 143 115 4-0 1-1 4W
Louisville 4 1 180 105 75 3-1 1-0 1L
SMU 4 2 204 134 70 3-1 1-1 2W
Wake Forest 4 2 174 120 54 2-2 2-0 2W
Pittsburgh 4 2 239 129 110 3-1 1-1 2W
Duke 4 2 219 153 66 2-1 2-1 3W
California 4 2 145 135 10 2-1 2-1 1L
NC State 4 3 210 186 24 3-1 1-2 1L
Clemson 3 3 158 111 47 1-2 2-1 2W
Florida State 3 3 265 138 127 3-2 0-1 3L
Syracuse 3 3 174 179 -5 2-1 1-2 2L
North Carolina 2 3 94 129 -35 1-2 1-1 2L
Stanford 2 4 113 181 -68 2-0 0-4 1L
Virginia Tech 2 5 161 205 -44 1-3 1-2 2L
Boston College 1 5 167 199 -32 1-2 0-3 5L
Southeastern W L PF PA N. Pts Home Away Strk
Ole Miss 6 0 227 115 112 5-0 1-0 6W
Texas A&M 6 0 208 122 86 5-0 1-0 6W
Alabama 5 1 209 104 105 3-0 2-1 5W
Georgia 5 1 193 102 91 3-1 2-0 2W
LSU 5 1 155 71 84 4-0 1-1 1W
Missouri 5 1 250 100 150 5-1 0-0 1L
Oklahoma 5 1 175 59 116 4-0 1-1 1L
Tennessee 5 1 289 176 113 4-1 1-0 3W
Vanderbilt 5 1 259 116 143 3-0 2-1 1L
Mississippi State 4 2 202 119 83 3-1 1-1 2L
Texas 4 2 171 66 105 4-0 0-2 1W
Auburn 3 3 148 102 46 2-1 1-2 3L
South Carolina 3 3 134 114 20 3-1 0-2 1L
Kentucky 2 3 122 139 -17 2-1 0-2 2L
Arkansas 2 4 218 184 34 2-1 0-3 4L
Florida 2 4 134 119 15 2-1 0-3 1L