Ohio State vs Illinois Prediction, Picks & Odds | 11 Oct 2025

College Football Betting Preview: Ohio State vs Illinois

Ohio State lock horns with Illinois in this NCAAF Week 7 matchup at Memorial Stadium, with kickoff scheduled for 12:00 on Saturday 11 October. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.

Illini Betting Line Looks Too Generous

It’s hard to resist wagering Illinois considering they’ve been given +14.5 on the spread. The underdogs are a good shout at -114 to stay close to Ohio State.

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Each Team Won Previous Clash

Ohio State Buckeyes made it five consecutive wins after a 42-3 home success over Minnesota Golden Gophers at Ohio Stadium.

Illinois Fighting Illini have now achieved three straight home wins. In their last game, they won on the road at Ross-Ade Stadium when beating Purdue Boilermakers 43-27.

Quarterbacks

Julian Sayin

270.5 Passing Yards

Over -114

Under -114

Luke Altmyer

210.5 Passing Yards

Over -114

Under -114

Ohio State vs Illinois Prediction & Picks

Our Ohio State vs Illinois betting tips provide expert coverage of all major angles, including our main match prediction, top player prop picks, correct score recommendation and best bet builder insights.

Game Prediction

The best bet could be Illinois at -114 on the spread. The underdogs been given a +14.5 points start and should be able to stay relatively close to their opponents in this college football matchup.

To deliver the best possible college football picks, we start by locking in the team news and taking time to review the latest form. There’s also no shortage of data to crunch from the most up-to-date stats available.

Key Ohio State vs Illinois stats:

• The +14.5 line has been covered by Illinois in 16 consecutive games at home.
• The +14.5 line has been covered by Illinois in 19 of their last 20 games at home.
• The -14.5 line hasn’t been covered by Ohio State in 12 of their last 20 games on the road.

Illini +14.5 Probability

According to the latest betting odds, our pick has a 53.2% chance of winning. Taking all factors into consideration, our experts think there’s a stronger chance of success and estimate the probability to be closer to 60%. It's therefore regarded as a value wager.

Those wanting an alternative to the spread can consider Winning Margin where there are several options. Take a view on Illini and their performance.

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Best Bet

Illinois +14.5 @ -114 Bet Now

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Player Prop Picks

Top Pick: Julian Sayin Under 270.5 Passing Yards -114

You can back Julian Sayin (Ohio State) at -114 to end with fewer than 270.5 passing yards. He is likely to fall short of the line, making this QB Passing Yards bet an appealing option.

Latest Julian Sayin Player Prop Odds

Passing Yards

Over 270.5

-114

Under 270.5

-114

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Carnell Tate Under 68.5 Receiving Yards -114

The odds for Carnell Tate (Illini) to have less than 68.5 receiving yards are -114. Several factors suggest he will fall short of the Player Receiving Yards line, making this an appealing wager.

Latest Carnell Tate Player Prop Odds

Receiving Yards

Over 68.5

-114

Under 68.5

-114

Correct Score Prediction

Ohio State 30 - 23 Illinois

For those looking to get more bang for their buck, consider a correct score wager on the Buckeyes. Backing them to win 30-23 means you can land a potential monster return.

Ohio State vs Illinois Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Books Taking No Chances With Ohio State

At betting odds of -625 with the sportsbooks, Ohio State are regarded as 86% likely to win this college game. Illinois are trading at bigger odds than their opponents and they can be backed at +460.

The current spread is 14.5 and total points is 50.5. The Totals offers football bettors an alternative way of getting involved. If you’re going for Under 50.5, this outcome can be backed at -106.

Whether you are betting pre-game or in-game on college football, the best sportsbooks let you feast on a wide range of game lines and team props. The selections are practically endless, and it’s fantastic to have so many options.

Moneyline

Ohio State

-625

Illini

+460

Point Spread

Ohio State -14.5

-106

Illini +14.5

-114

Total Points

Under 50.5

-106

Over 50.5

-114

Player Odds

Receiving Yards

Jeremiah Smith (Ohio State)

Over 91.5

-114

Under 91.5

-114

Carnell Tate (Ohio State)

Over 68.5

-114

Under 68.5

-114

Hank Beatty (Illini)

Over 60.5

-114

Under 60.5

-114

Collin Dixon (Illini)

Over 31.5

-114

Under 31.5

-114

Max Klare (Ohio State)

Over 26.5

-114

Under 26.5

-114

Rushing Yards

Bo Jackson (Ohio State)

Over 72.5

-114

Under 72.5

-114

CJ Donaldson (Ohio State)

Over 27.5

-114

Under 27.5

-114

Passing Yards

Julian Sayin (Ohio State)

Over 270.5

-114

Under 270.5

-114

Luke Altmyer (Illini)

Over 210.5

-114

Under 210.5

-114

Will Illini Extend Their Home Winning Streak?

Illinois have chalked up four straight victories at Memorial Stadium. They have gone 9-1 across their last 10 home games, averaging 34.80 points scored and 15.80 points allowed.

Ohio State have stacked up six consecutive road wins. They have gone 8-2 across their last 10 road games, posting 30.60 points per contest while yielding 16.90.

Last 10 Games		W-L	P	PF	PA	O49.5	U49.5
Illinois Home Stats		9-1	50.60	34.80	15.80	4	6
Ohio State Away Stats		8-2	47.50	30.60	16.90	5	5

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O49.5 = Games Over 49.5 Points
• U49.5 = Games Under 49.5 Points

Last 5 & H2H

Latest regular season and playoff games stats.

Ohio State Buckeyes Stats

Illinois Fighting Illini Stats

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 8 wins and 2 defeats in the last 10 games on the road

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• -14.5 Betting Line: Have covered the spread in 6 of the last 10 games
• -14.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• +14.5 Betting Line: Have covered the spread in 9 of the last 10 games
• +14.5 Betting Line at Home: Have covered the spread in the last 10 home games

Total Points

• Game Totals: An average of 45.50 pts in the previous 10 games
• Game Totals on the Road: An average of 47.50 pts in the previous 10 games on the road
• Over 49.5: Covered in 4 of the previous 10 games
• Over 49.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 34.20 pts and allowed 11.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 30.60 pts and allowed 16.90 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 59.30 pts in the previous 10 games
• Game Totals at Home: An average of 49.90 pts in the previous 10 home games
• Over 49.5: Covered in 8 of the previous 10 games
• Over 49.5 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 35.70 pts and allowed 23.60 pts in the last 10 games
• Team Totals at Home: Have scored an average of 32.40 pts and allowed 17.50 pts in the last 10 home games

NCAAF Standings Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big Ten	W	L	PF	PA	N. Pts	Home	Away	Strk
Indiana	5	0	239	48	191	4-0	1-0	5W
Oregon	5	0	233	61	172	3-0	2-0	5W
Ohio State	5	0	187	25	162	4-0	1-0	5W
Illinois	5	1	222	144	78	3-0	2-1	2W
Maryland	4	1	150	67	83	3-1	1-0	1L
Michigan	4	1	164	81	83	3-0	1-1	3W
Nebraska	4	1	212	81	131	3-1	1-0	1W
USC	4	1	242	115	127	3-0	1-1	1L
Washington	4	1	197	99	98	2-1	2-0	1W
Penn State	3	2	193	89	104	3-1	0-1	2L
Rutgers	3	2	195	127	68	3-1	0-1	2L
Iowa	3	2	147	78	69	2-1	1-1	1L
Northwestern	3	2	118	85	33	3-1	0-1	2W
Minnesota	3	2	137	107	30	3-0	0-2	1L
Michigan State	3	2	164	153	11	3-0	0-2	2L
Purdue	2	3	139	149	-10	2-2	0-1	3L
Wisconsin	2	3	93	99	-6	2-1	0-2	3L
UCLA	1	4	99	162	-63	1-2	0-2	1W