Ohio State vs Illinois Prediction, Picks & Odds | 11 Oct 2025
College Football Betting Preview: Ohio State vs Illinois
Ohio State lock horns with Illinois in this NCAAF Week 7 matchup at Memorial Stadium, with kickoff scheduled for 12:00 on Saturday, October 11. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.
Illini Betting Line Looks Too Generous
It’s hard to resist wagering Illinois considering they’ve been given +14.5 on the spread. The underdogs are a good shout at -114 to stay close to Ohio State.
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Each Team Won Previous Clash
Ohio State Buckeyes made it five consecutive wins after a 42-3 home success over Minnesota Golden Gophers at Ohio Stadium.
Illinois Fighting Illini have now achieved three straight home wins. In their last game, they won on the road at Ross-Ade Stadium when beating Purdue Boilermakers 43-27.
Quarterbacks
Julian Sayin
Luke Altmyer
Ohio State vs Illinois Prediction & Picks
Our Ohio State vs Illinois betting tips provide expert coverage of all major angles, including our main match prediction, top player prop picks, correct score recommendation and best bet builder insights.
Game Prediction
The best bet could be Illinois at -114 on the spread. The underdogs been given a +14.5 points start and should be able to stay relatively close to their opponents in this college football matchup.
To deliver the best possible college football picks, we start by locking in the team news and taking time to review the latest form. There’s also no shortage of data to crunch from the most up-to-date stats available.
Key Ohio State vs Illinois stats:
Illini +14.5 Probability
According to the latest betting odds, our pick has a 53.2% chance of winning. Taking all factors into consideration, our experts think there’s a stronger chance of success and estimate the probability to be closer to 60%. It's therefore regarded as a value wager.
Those wanting an alternative to the spread can consider Winning Margin where there are several options. Take a view on Illini and their performance.
Don’t miss the chance to claim free bets using our exclusive betting promo codes —check our bonus guide before placing your bets.
Best Bet
Illinois +14.5 @ -114
Player Prop Picks
You can back Julian Sayin (Ohio State) at -114 to end with fewer than 270.5 passing yards. He is likely to fall short of the line, making this QB Passing Yards bet an appealing option.
The odds for Carnell Tate (Illini) to have less than 68.5 receiving yards are -114. Several factors suggest he will fall short of the Player Receiving Yards line, making this an appealing wager.
Same Game Parlay Picks
We’ve loaded up a same game parlay with the combined picks of Illinois +14.5, Over 49.5 and Julian Sayin (Ohio State) to go Under 270.5 passing yards.
A same game parlay is an awesome way of cheering on different outcomes within the same football game. You can predict a number of outcomes and get bigger odds than a single wager. The odds can combine to great effect.
Correct Score Prediction
30
-
23
Illinois
For those looking to get more bang for their buck, consider a correct score wager on the Buckeyes. Backing them to win 30-23 means you can land a potential monster return.
Ohio State vs Illinois Odds
The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.
Books Taking No Chances With Ohio State
At betting odds of -526 with the sportsbooks, Ohio State are regarded as 84% likely to win this college game. Illinois are trading at bigger odds than their opponents and they can be backed at +390.
The current spread is 13.5 and total points is 50.5. The Totals offers football bettors an alternative way of getting involved. If you’re going for Under 50.5, this outcome can be backed at -110.
Whether you are betting pre-game or in-game on college football, the best sportsbooks let you feast on a wide range of game lines and team props. The selections are practically endless, and it’s fantastic to have so many options.
Jeremiah Smith Favorite to Be First Touchdown Scorer
Jeremiah Smith is the First Touchdown Scorer favorite at +370. Alternatively, there’s the opportunity to simply back him to score a TD anytime at -185.
Touchdown
Receiving Yards
Rushing Yards
Passing Yards
Micro Betting
Micro betting provides a rollercoaster ride for college football bettors. It can be great to enjoy the live lines, with the opportunity to wager on the Next Scoring Play. Watch the live action before deciding which way to go.
Will Illini Extend Their Home Winning Streak?
Illinois have chalked up four straight victories at Memorial Stadium. They have gone 9-1 across their last 10 home games, averaging 34.80 points scored and 15.80 points allowed.
Ohio State have stacked up six consecutive road wins. They have gone 8-2 across their last 10 road games, posting 30.60 points per contest while yielding 16.90.
| Last 10 Games | W-L | P | PF | PA | O49.5 | U49.5 | |
|---|---|---|---|---|---|---|---|
 Illinois Home Stats |
9-1 | 50.60 | 34.80 | 15.80 | 4 | 6 | |
 Ohio State Away Stats |
8-2 | 47.50 | 30.60 | 16.90 | 5 | 5 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O49.5 = Games Over 49.5 Points
- U49.5 = Games Under 49.5 Points
Last 5 & H2H
Latest regular season and playoff games stats.
Ohio State Buckeyes Stats
Illinois Fighting Illini Stats
- 9 wins and 1 defeat in the last 10 games
- 8 wins and 2 defeats in the last 10 games on the road
- -14.5 Betting Line: Have covered the spread in 6 of the last 10 games
- -14.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road
- +14.5 Betting Line: Have covered the spread in 9 of the last 10 games
- +14.5 Betting Line at Home: Have covered the spread in the last 10 home games
- Game Totals: An average of 45.50 pts in the previous 10 games
- Game Totals on the Road: An average of 47.50 pts in the previous 10 games on the road
- Over 49.5: Covered in 4 of the previous 10 games
- Over 49.5 on the Road: Covered in 5 of the previous 10 games on the road
- Team Totals: Have scored an average of 34.20 pts and allowed 11.30 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 30.60 pts and allowed 16.90 pts in the last 10 games on the road
- Game Totals: An average of 59.30 pts in the previous 10 games
- Game Totals at Home: An average of 49.90 pts in the previous 10 home games
- Over 49.5: Covered in 8 of the previous 10 games
- Over 49.5 at Home: Covered in 4 of the previous 10 home games
- Team Totals: Have scored an average of 35.70 pts and allowed 23.60 pts in the last 10 games
- Team Totals at Home: Have scored an average of 32.40 pts and allowed 17.50 pts in the last 10 home games
NCAAF Standings Select Season
| Big Ten | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Indiana
|
10 | 0 | 445 | 121 | 324 | 6-0 | 4-0 | 10W |
|
Ohio State
|
9 | 0 | 327 | 65 | 262 | 5-0 | 4-0 | 9W |
Oregon
|
8 | 1 | 348 | 124 | 224 | 4-1 | 4-0 | 3W |
Michigan
|
7 | 2 | 253 | 155 | 98 | 5-0 | 2-2 | 3W |
USC
|
7 | 2 | 356 | 196 | 160 | 5-0 | 2-2 | 2W |
Nebraska
|
7 | 3 | 325 | 199 | 126 | 4-2 | 3-1 | 1W |
Minnesota
|
6 | 3 | 214 | 194 | 20 | 6-0 | 0-3 | 1W |
Iowa
|
6 | 3 | 266 | 123 | 143 | 4-2 | 2-1 | 1L |
Washington
|
6 | 3 | 294 | 180 | 114 | 4-1 | 2-2 | 1L |
|
Illinois
|
6 | 3 | 298 | 233 | 65 | 4-1 | 2-2 | 1W |
Northwestern
|
5 | 4 | 197 | 172 | 25 | 4-1 | 1-3 | 2L |
Rutgers
|
5 | 5 | 299 | 300 | -1 | 4-2 | 1-3 | 1W |
Maryland
|
4 | 5 | 228 | 211 | 17 | 3-3 | 1-2 | 5L |
UCLA
|
3 | 6 | 184 | 276 | -92 | 2-3 | 1-3 | 2L |
Wisconsin
|
3 | 6 | 113 | 201 | -88 | 3-3 | 0-3 | 1W |
Michigan State
|
3 | 6 | 230 | 283 | -53 | 3-2 | 0-4 | 6L |
Penn State
|
3 | 6 | 276 | 201 | 75 | 3-3 | 0-3 | 6L |
Purdue
|
2 | 8 | 209 | 277 | -68 | 2-4 | 0-4 | 8L |
Kent State
Akron
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Burgos
Castellón
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