Oklahoma vs South Carolina Prediction, Picks & Odds | 18 Oct 2025
College Football Betting Preview: Oklahoma vs South Carolina
Oklahoma clash with South Carolina in this NCAAF Week 8 matchup at Williams-Brice Stadium, with kickoff scheduled for 12:45 on Saturday 18 October. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.
South Carolina to Frustrate Oklahoma
The line makes plenty of appeal considering it’s set at +5.5 and our prediction is that South Carolina will cover this against Oklahoma. There is -105 available for this outcome.
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South Carolina Won 35-9 When Teams Last Met
Oklahoma Sooners lost in their previous game. Texas Longhorns won 23-6 at Cotton Bowl Stadium.
South Carolina Gamecocks suffered a defeat in their last game. A 20-10 scoreline occurred on the road at Tiger Stadium against LSU Tigers.
Head-to-Head Statistics
South Carolina won the last matchup between the pair. Enjoying a 35-9 triumph when facing Oklahoma at Gaylord Family Memorial Stadium.
Quarterbacks
John Mateer
LaNorris Sellers
Oklahoma vs South Carolina Prediction & Picks
Our Oklahoma vs South Carolina betting tips provide expert coverage of all major angles, including our main match prediction, top player prop picks, correct score recommendation and best bet builder insights.
Game Prediction
Our best bet is South Carolina at +5.5 on the spread. A win or narrow defeat would mean our pick at -105 lands a really nice return for this college football matchup.
Our CFB handicappers start by reviewing the latest team news for each team, followed by a close look at recent form. That information is then applied to the most relevant stats to reach a well-informed verdict.
Key Oklahoma vs South Carolina stats:
South Carolina +5.5 Probability
Looking at the latest betting odds, our pick has a 51.3% chance of winning. After careful examination, our cappers have this probability close to 60%. This is why we regard this as a value bet.
If the initial odds don’t grab your fancy, there’s the option to shoot for more juice by moving the line when it comes to your spread pick. It all comes down to how confident you feel.
Before you make your picks, explore our detailed betting guide filled with free bets, the latest promo codes and welcome bonuses.
Best Bet
South Carolina +5.5 @ -105
Player Prop Picks
You can place a bet on John Mateer (Oklahoma) at -114 to have less than 235.5 passing yards. Several factors suggest he will fall short of the QB Passing Yards line, making this an appealing wager.
You can place a bet on Rahsul Faison (South Carolina) at -114 to record fewer than 37.5 rushing yards. He could struggle to reach the Player Rushing Yards line, making this prop bet highly appealing.
Same Game Parlay Picks
Get in the game with a same game parlay. Our picks are South Carolina to cover the +5.5 spread, Under 43.5 on the total and John Mateer (Oklahoma) to have Under 235.5 passing yards.
There are many options when you place a same game parlay. You can go through the football lines and identify your favorite outcomes before combining the odds on the bet slip. Personalised betting doesn’t come any better.
Correct Score Prediction
17
-
21
South Carolina
We’re expecting a close battle so it might be worth going for South Carolina to triumph by a 21-17 scoreline. You can get a massive price and we should hopefully get a run for our money.
Oklahoma vs South Carolina Odds
The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.
Oklahoma Made Favorites by the Books
The sportsbooks have Oklahoma at -175 when it comes to the Moneyline betting, implying the market leaders are 64% likely to win this college game according to the latest odds. South Carolina are the underdogs at +146 and they’re regarded as least likely to win.
There is a spread of 3.5 and total points has a line of 42.5. There is no denying the popularity of wagering on the Totals. There’s the chance to back Under 42.5 at -110.
When it comes to college football, the top betting apps deliver a wide variety of game lines and team props. With so many options available, it’s worth taking your time to find the wager that fits your view of the matchup.
John Mateer Favorite to Be First TD Scorer
John Mateer can be backed to score a touchdown at anytime at +110. He is the favorite to score the first TD at odds of +650.
Touchdown
Receiving Yards
Rushing Yards
Passing Yards
Micro Betting
Among the various options for wagering on college football, you will find that micro betting is provided. It focuses on short-term in-game outcomes such as whether a touchdown will be scored within the next few minutes.
South Carolina Own Seven Victories From Previous Ten at Home
South Carolina have a 7-3 record in their last 10 home games, averaging 32.30 points on offense and surrendering 20.50 on defense.
Oklahoma have gone 3-7 across their last 10 games games on the road, scoring 23.70 points per contest and conceding 25.00.
| Last 10 Games | W-L | P | PF | PA | O43.5 | U43.5 | |
|---|---|---|---|---|---|---|---|
 South Carolina Home Stats |
7-3 | 52.80 | 32.30 | 20.50 | 7 | 3 | |
 Oklahoma Away Stats |
3-7 | 48.70 | 23.70 | 25.00 | 7 | 3 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O43.5 = Games Over 43.5 Points
- U43.5 = Games Under 43.5 Points
Last 5 & H2H
Latest regular season and playoff games stats.
Oklahoma Sooners Stats
South Carolina Gamecocks Stats
- 6 wins and 4 defeats in the last 10 games
- 3 wins and 7 defeats in the last 10 games on the road
- -5.5 Betting Line: Have covered the spread in 6 of the last 10 games
- -5.5 Betting Line on the Road: Have covered the spread in 3 of the last 10 games on the road
- +5.5 Betting Line: Have covered the spread in 7 of the last 10 games
- +5.5 Betting Line at Home: Have covered the spread in 8 of the last 10 home games
- Game Totals: An average of 40.90 pts in the previous 10 games
- Game Totals on the Road: An average of 48.70 pts in the previous 10 games on the road
- Over 43.5: Covered in 4 of the previous 10 games
- Over 43.5 on the Road: Covered in 7 of the previous 10 games on the road
- Team Totals: Have scored an average of 25.90 pts and allowed 15.00 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 23.70 pts and allowed 25.00 pts in the last 10 games on the road
- Game Totals: An average of 44.90 pts in the previous 10 games
- Game Totals at Home: An average of 52.10 pts in the previous 10 home games
- Over 43.5: Covered in 5 of the previous 10 games
- Over 43.5 at Home: Covered in 7 of the previous 10 home games
- Team Totals: Have scored an average of 25.80 pts and allowed 19.10 pts in the last 10 games
- Team Totals at Home: Have scored an average of 32.40 pts and allowed 19.70 pts in the last 10 home games
NCAAF Standings Select Season
| Southeastern | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Texas A&M
|
7 | 0 | 253 | 164 | 89 | 5-0 | 2-0 | 7W |
Alabama
|
6 | 1 | 246 | 124 | 122 | 4-0 | 2-1 | 6W |
Georgia
|
6 | 1 | 236 | 137 | 99 | 4-1 | 2-0 | 3W |
Missouri
|
6 | 1 | 273 | 117 | 156 | 5-1 | 1-0 | 1W |
|
Oklahoma
|
6 | 1 | 201 | 66 | 135 | 4-0 | 2-1 | 1W |
Ole Miss
|
6 | 1 | 262 | 158 | 104 | 5-0 | 1-1 | 1L |
Vanderbilt
|
6 | 1 | 290 | 140 | 150 | 4-0 | 2-1 | 1W |
LSU
|
5 | 2 | 179 | 102 | 77 | 4-0 | 1-2 | 1L |
Tennessee
|
5 | 2 | 309 | 213 | 96 | 4-1 | 1-1 | 1L |
Texas
|
5 | 2 | 187 | 79 | 108 | 4-0 | 1-2 | 2W |
Mississippi State
|
4 | 3 | 223 | 142 | 81 | 3-1 | 1-2 | 3L |
Auburn
|
3 | 4 | 165 | 125 | 40 | 2-2 | 1-2 | 4L |
Florida
|
3 | 4 | 157 | 140 | 17 | 3-1 | 0-3 | 1W |
|
South Carolina
|
3 | 4 | 141 | 140 | 1 | 3-2 | 0-2 | 2L |
Kentucky
|
2 | 4 | 135 | 155 | -20 | 2-2 | 0-2 | 3L |
Arkansas
|
2 | 5 | 260 | 229 | 31 | 2-2 | 0-3 | 5L |
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