Old Dominion vs Indiana Prediction, Picks & Odds | 30 Aug 2025

College Football Betting Preview: Old Dominion vs Indiana

Old Dominion lock horns with Indiana in this NCAAF Week 1 matchup at Memorial Stadium, with kickoff scheduled for 14:30 on Saturday, August 30. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.

Indiana should enjoy a big win and that’s why we’re taking the -23.5 about the favorites on the spread. This recommendation should cover the line at -115 against Old Dominion.

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Old Dominion Monarchs won their previous game by a 40-32 scoreline. It was on the road against Arkansas State Red Wolves at Centennial Bank Stadium.

Indiana Hoosiers lost their last game, falling 27–17 on the road to the Notre Dame Fighting Irish in the College Football Playoff First Round at Notre Dame Stadium.

Old Dominion vs Indiana Prediction & Picks

Our Old Dominion vs Indiana tips include the main match prediction, a correct score forecast and bet builder picks. Each section below offers expert insight into the key betting angles.

Game Prediction

We’re predicting that this could be a one-sided college football affair. Our pick is to therefore take Indiana at -115 to cover an appealing -23.5 line on the spread.

Knowing which players are injured gives us a valuable edge when making college football predictions. After reviewing the form guide, we turn to the latest stats to shape our picks.

Key Old Dominion vs Indiana stats:

• The -23.5 line has been covered by Indiana in 5 of their last 10 games at home.

Indiana -23.5 Probability

Based on the odds from the top sportsbooks, our pick has a 53.5% chance of winning. In the opinion of our analysts, there’s actually a probability of success closer to 60%. The wager can be recommended for this precise reason.

There are lots of ways to back Indiana and that includes the Winning Margin lines. Choose from a range of fixed intervals and get rewarded if you’re on the money.

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Our Game Prediction

Indiana -23.5 @ -115 Bet Now

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Correct Score Prediction

Old Dominion 14 - 42 Indiana

Rather than backing the Hoosiers to triumph, there’s the alternative to try your luck when it comes to the correct score lines. Take a chance on a 42-14 win in their favor.

Old Dominion vs Indiana Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

The sportsbooks are taking no chances with their Moneyline odds of -3333 about Indiana which reflects they have a 97% chance of winning this college game. For those wanting to oppose the market leader, you can get +1200 about Old Dominion.

The spread currently stands at 23.5 and the total points line is 53.5. A Total wager is always available and can often provide value selections. There’s the chance to back Under 53.5 at -110.

You can find a nice selection of game lines and team props for every college football game, with the top betting apps creating many different options. Check out the pre-game and in-game selections before placing your bets.

Moneyline

Old Dominion

+1200

Indiana

-3333

Point Spread

Old Dominion +23.5

-105

Indiana -23.5

-115

Total Points

Under 53.5

-110

Over 53.5

-110

If you’re looking for an alternative to the main game lines, check out the player props instead. It’s great to bet on Quarterback Passing Yards, First Touchdown Scorer and Passing Touchdowns as potential options.

There are always opportunities to enjoy college football micro betting. It’s generally the case that you will find player and team props in-game and bettors can use their insight to wager on outcomes such as the Next Punt, Turnover or Score Play.

Indiana Locked In at Home

Indiana have put together eight wins in a row at Memorial Stadium. They have a 9-1 record in their last 10 home games, posting 41.60 points per contest while yielding 12.90.

Old Dominion have a 5-5 record in their last 10 road games, putting up 24.10 points per contest and giving up 26.70.

Last 10 Games		W-L	P	PF	PA	O52.5	U52.5
Indiana Home Stats		9-1	54.50	41.60	12.90	5	5
Old Dominion Away Stats		5-5	50.80	24.10	26.70	4	6

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O52.5 = Games Over 52.5 Points
• U52.5 = Games Under 52.5 Points

Latest regular season and playoff games stats.

Old Dominion Monarchs Stats

Indiana Hoosiers Stats

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• +23.5 Betting Line: Have covered the spread in the last 10 games
• +23.5 Betting Line on the Road: Have covered the spread in 9 of the last 10 games on the road

Point Spread

• -23.5 Betting Line: Have covered the spread in 4 of the last 10 games
• -23.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games

Total Points

• Game Totals: An average of 59.60 pts in the previous 10 games
• Game Totals on the Road: An average of 50.80 pts in the previous 10 games on the road
• Over 52.5: Covered in 7 of the previous 10 games
• Over 52.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 30.30 pts and allowed 29.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 24.10 pts and allowed 26.70 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 56.70 pts in the previous 10 games
• Game Totals at Home: An average of 54.50 pts in the previous 10 home games
• Over 52.5: Covered in 7 of the previous 10 games
• Over 52.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 38.70 pts and allowed 18.00 pts in the last 10 games
• Team Totals at Home: Have scored an average of 41.60 pts and allowed 12.90 pts in the last 10 home games

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