Old Dominion vs South Florida Prediction, Picks & Odds | 17 Dec 2025
College Football Betting Preview: Old Dominion vs South Florida
Old Dominion square off against South Florida in the Cure Bowl at Camping World Stadium, with kickoff scheduled for 17:00 on Wednesday, December 17.
The total line of 53.5 points looks pretty low and we can take advantage by backing the Overs at -110. We can see South Florida and Old Dominion combining to go bigger.
Think the passing game goes off here? Snag the latest BetMGM promo code and weigh up our in-depth review before putting your money down.
Old Dominion Monarchs made it five consecutive wins after a 27-10 home success over Georgia State Panthers at S.B. Ballard Stadium.
South Florida last game was a 52-3 victory over Rice Owls at Raymond James Stadium. That means it’s now been six home wins on the spin.
Quarterbacks
Quinn Henicle
Gaston Moore
Old Dominion vs South Florida Prediction & Picks
Get the full betting picture for Old Dominion vs South Florida, including our expert match prediction, likely scoreline, must-watch player props and a tailored bet builder ready to use.
Game Prediction
We’ll take a chance on a total bet after finding that the line is set at a generous 53.5 points. Expect this number to be surpassed at -110 for this Cure Bowl college football matchup.
We put solid research behind every CFB pick, starting with recent form and a clear read on injuries. From there, key stats and advanced metrics help complete the picture and support smarter betting decisions.
Key Old Dominion vs South Florida stats:
Over 53.5 Probability
Based on the odds from the top sportsbooks, our pick has a 52.4% chance of winning. Based on our analysts in-depth research, we calculate the actual probability to be closer to 60%. The bet can be recommended for this precise reason.
Secure more attractive betting odds by moving the line when you place an Over wager. You can choose from a range of options on the Totals until you’re happy with your bet.
Check out the most rewarding betting offers in our in-depth guide before your next wager. The best bonuses and free bets await.
Player Prop Picks
Gaston Moore (USF) is priced at -114 to go over 183.5 passing yards. We feel confident that he’ll cover the QB Passing Yards line, which looks generous.
The odds for Sam Franklin (Old Dominion) to exceed 41.5 rushing yards are -114. We’re confident in taking him to cover the Player Rushing Yards line and bettors can place this bet with confidence.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
We’ve got a same game parlay with three options: Over 53.5 points, South Florida -2.5 and Gaston Moore (South Florida) to have Over 183.5 passing yards.
A same game parlay allows bettors to place a multiple wager on the same football game. You can go through the available betting lines and cherry-pick the outcomes that you think will happen. The odds for each selection are then combined together.
Correct Score Prediction
27
-
31
South Florida
Don’t pass up the opportunity to have a speculative bet on the Bulls to land a 31-27 win. We don’t think that there will be too much between the teams.
Old Dominion vs South Florida Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
The sportsbooks’ betting odds have South Florida as -192 favorites for this college game, implying that they are 66% likely to win. For those wanting to oppose the market leader, you can get +162 about Old Dominion.
The spread is calculated to be 3.5, while total points comes in at 52.5. There are many ways to wager on football including the Totals. If you want to back Over 52.5, it’s -110.
You can find a nice selection of game lines and team props for every college football game, with the top betting apps creating many different options. Check out the pre-game and in-game selections before placing your bets.
The First TD Scorer favorite is Nykahi Davenport at +600. Similar odds can be found if you’re interested in this player to record the last touchdown.
Touchdown
Receiving Yards
Rushing Yards
Passing Yards
For those looking to enjoy a thrilling in-game wager, then college football micro betting could be up your street. You are now able to wager on what will happen on the next snap by staking your money on the Next Play Result.
Latest regular season and playoff games stats.
Old Dominion Monarchs Stats
South Florida Stats
- 8 wins and 2 defeats in the last 10 games
- 5 wins and 5 defeats in the last 10 games on the road
- +2.5 Betting Line: Have covered the spread in 8 of the last 10 games
- +2.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road
- -2.5 Betting Line: Have covered the spread in 7 of the last 10 games
- -2.5 Betting Line at Home: Have covered the spread in 8 of the last 10 home games
- Game Totals: An average of 52.20 pts in the previous 10 games
- Game Totals on the Road: An average of 60.30 pts in the previous 10 games on the road
- Over 53.5: Covered in 5 of the previous 10 games
- Over 53.5 on the Road: Covered in 6 of the previous 10 games on the road
- Team Totals: Have scored an average of 32.40 pts and allowed 19.80 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 30.40 pts and allowed 29.90 pts in the last 10 games on the road
- Game Totals: An average of 72.10 pts in the previous 10 games
- Game Totals at Home: An average of 60.40 pts in the previous 10 home games
- Over 53.5: Covered in the previous 10 games
- Over 53.5 at Home: Covered in 7 of the previous 10 home games
- Team Totals: Have scored an average of 46.40 pts and allowed 25.70 pts in the last 10 games
- Team Totals at Home: Have scored an average of 41.40 pts and allowed 19.00 pts in the last 10 home games
| American Athletic | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Tulane
|
11 | 2 | 378 | 294 | 84 | 7-0 | 4-2 | 5W |
North Texas
|
11 | 2 | 582 | 324 | 258 | 6-1 | 5-1 | 1L |
Navy
|
10 | 2 | 374 | 312 | 62 | 7-0 | 3-2 | 3W |
|
South Florida
|
9 | 3 | 516 | 280 | 236 | 6-0 | 3-3 | 2W |
East Carolina
|
8 | 4 | 402 | 244 | 158 | 5-1 | 3-3 | 1W |
Memphis
|
8 | 4 | 415 | 270 | 145 | 4-2 | 4-2 | 3L |
Army
|
6 | 6 | 269 | 265 | 4 | 2-3 | 4-3 | 1L |
UTSA
|
6 | 6 | 405 | 355 | 50 | 4-2 | 2-4 | 1L |
Temple
|
5 | 7 | 334 | 356 | -22 | 2-4 | 3-3 | 4L |
Rice
|
5 | 7 | 238 | 387 | -149 | 3-4 | 2-3 | 2L |
Florida Atlantic
|
4 | 8 | 354 | 436 | -82 | 3-3 | 1-5 | 3L |
UAB
|
4 | 8 | 317 | 459 | -142 | 3-3 | 1-5 | 1W |
Tulsa
|
4 | 8 | 278 | 347 | -69 | 2-4 | 2-4 | 1L |
Charlotte
|
1 | 11 | 172 | 436 | -264 | 1-6 | 0-5 | 9L |
| Sun Belt | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
James Madison
|
12 | 1 | 485 | 206 | 279 | 7-0 | 5-1 | 11W |
|
Old Dominion
|
9 | 3 | 392 | 231 | 161 | 6-0 | 3-3 | 5W |
Troy
|
8 | 5 | 316 | 318 | -2 | 4-2 | 4-3 | 1L |
Southern Miss
|
7 | 5 | 358 | 329 | 29 | 4-3 | 3-2 | 3L |
Coastal Carolina
|
6 | 6 | 274 | 407 | -133 | 4-2 | 2-4 | 3L |
Arkansas State
|
6 | 6 | 293 | 328 | -35 | 3-3 | 3-3 | 1W |
Louisiana
|
6 | 6 | 325 | 360 | -35 | 4-2 | 2-4 | 4W |
Georgia Southern
|
6 | 6 | 334 | 410 | -76 | 4-2 | 2-4 | 1W |
Texas State
|
6 | 6 | 433 | 367 | 66 | 4-2 | 2-4 | 3W |
Marshall
|
5 | 7 | 369 | 363 | 6 | 3-3 | 2-4 | 2L |
Appalachian State
|
5 | 7 | 304 | 358 | -54 | 3-3 | 2-4 | 1L |
South Alabama
|
4 | 8 | 318 | 365 | -47 | 2-4 | 2-4 | 1L |
UL Monroe
|
3 | 9 | 199 | 383 | -184 | 2-3 | 1-6 | 8L |
Georgia State
|
1 | 11 | 237 | 454 | -217 | 1-5 | 0-6 | 9L |
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