Oregon vs Penn State Prediction, Picks & Odds | 27 Sep 2025
College Football Betting Preview: Oregon vs Penn State
Oregon battle Penn State in this NCAAF Week 5 matchup at Beaver Stadium, with kickoff scheduled for 19:30 on Saturday 27 September. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.
Penn State Against the Spread Look the Best Bet
Bet on Penn State against the spread in order to get the best value. They should be able to cover a generous -3.5 line at -112 in their clash against Oregon.
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Oregon Won 45-37 in Teams’ Previous H2H
Oregon Ducks have won their previous four games. The latest was a 41-7 home triumph at Autzen Stadium against Oregon State Beavers.
Penn State Nittany Lions last game was a 52-6 home win. This victory over Villanova at Beaver Stadium was their third successive victory.
Head-to-Head Statistics
These two teams last met at Lucas Oil Stadium, with Oregon claiming the win. Beating Penn State by a 45-37 scoreline.
Quarterbacks
Dante Moore
Drew Allar
Oregon vs Penn State Prediction & Picks
Our Oregon vs Penn State betting preview covers everything you need, including a key match prediction, correct score insight, top player prop bets and a value-packed bet builder recommendation.
Game Prediction
Bet on Penn State against the spread, with an attractive line of -3.5 that the favorites get the job done. There are odds of -112 that are currently on offer for this college football matchup.
We use the latest team news and injury updates to help shape the best possible CFB predictions. You’ll also notice we take a stats-led approach by factoring in the key numbers that truly make a difference.
Key Oregon vs Penn State stats:
Penn State -3.5 Probability
Based on the odds from the top sportsbooks, our pick has a 52.9% chance of winning. Taking all factors into consideration, our analysts think there’s a stronger chance of success and have a probability interval between 55-60%. This college wager can therefore be backed with confidence.
If the price on display doesn’t appeal, you can make the choice to secure bigger odds by moving the line for your selection. It’s a case of taking a view which you are happy with.
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Best Bet
Penn State -3.5 @ -112
Player Prop Picks
The odds for Kaytron Allen (Penn State) to hit paydirt are -125. We're happy to back this Anytime Touchdown Scorer bet, as the odds offer value for him to take it to the house at least once.
Nicholas Singleton (Oregon) is available at -114 to go over 64.5 rushing yards. The line for Player Rushing Yards looks attractive and we’re confident of securing a return.
Same Game Parlay Picks
Take a same game parlay that incorporates Penn State to cover the -3.5 spread along with Under 52.5 points. Add in Kaytron Allen (Penn State) as an anytime touchdown scorer.
A same game parlay allows bettors to place a multiple wager on the same football game. You can go through the available betting lines and cherry-pick the outcomes that you think will happen. The odds for each selection are then combined together.
Correct Score Prediction
17
-
30
Penn State
There are lots of different ways to back the Lions on the correct score betting and something like 30-17 in their favor might be along the right lines at massive odds.
Oregon vs Penn State Odds
The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.
Books Make Penn State Moneyline Favorites
Sportsbooks’ favorites Penn State are regarded as likeliest victors for this college game and the -179 about them triumphing means a 64% chance based on their current Moneyline betting odds. Oregon are regarded as a long shot to win and you can currently back them at +146.
3.5 is the spread and 53.5 is the total points line. The Totals offers football bettors an alternative way of getting involved. If you want to bet Under 53.5, there are odds of -110.
The best betting apps offer a wide range of game lines and team props when it comes to most college football games. Make sure you look through all the available options before deciding which bet to place.
Kaytron Allen Favorite to Be First Touchdown Scorer
You will find Kaytron Allen at +500 to be First Touchdown Scorer which makes him the favorite. There’s the opportunity to get -135 that he scores a TD at anytime.
Touchdown
Receiving Yards
Rushing Yards
Passing Yards
Penn State Looking to Keep Rolling at Home
Penn State have reeled off six straight victories at Beaver Stadium. They are 9-1 in their last 10 home games, averaging 36.60 points scored and 7.80 points allowed.
Oregon have strung together six straight wins on the road. They have gone 8-2 across their last 10 games on the road, putting up 35.40 points per contest and giving up 16.00.
| Last 10 Games | W-L | P | PF | PA | O52.5 | U52.5 | |
|---|---|---|---|---|---|---|---|
 Penn State Home Stats |
9-1 | 44.40 | 36.60 | 7.80 | 3 | 7 | |
 Oregon Away Stats |
8-2 | 51.40 | 35.40 | 16.00 | 5 | 5 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O52.5 = Games Over 52.5 Points
- U52.5 = Games Under 52.5 Points
Last 5 & H2H
Latest regular season and playoff games stats.
Oregon Ducks Stats
Penn State Nittany Lions Stats
- 9 wins and 1 defeat in the last 10 games
- 8 wins and 2 defeats in the last 10 games on the road
- +3.5 Betting Line: Have covered the spread in 9 of the last 10 games
- +3.5 Betting Line on the Road: Have covered the spread in the last 10 games on the road
- -3.5 Betting Line: Have covered the spread in 7 of the last 10 games
- -3.5 Betting Line at Home: Have covered the spread in 8 of the last 10 home games
- Game Totals: An average of 59.50 pts in the previous 10 games
- Game Totals on the Road: An average of 51.40 pts in the previous 10 games on the road
- Over 52.5: Covered in 7 of the previous 10 games
- Over 52.5 on the Road: Covered in 5 of the previous 10 games on the road
- Team Totals: Have scored an average of 41.10 pts and allowed 18.40 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 35.40 pts and allowed 16.00 pts in the last 10 games on the road
- Game Totals: An average of 53.60 pts in the previous 10 games
- Game Totals at Home: An average of 43.90 pts in the previous 10 home games
- Over 52.5: Covered in 4 of the previous 10 games
- Over 52.5 at Home: Covered in 2 of the previous 10 home games
- Team Totals: Have scored an average of 38.10 pts and allowed 15.50 pts in the last 10 games
- Team Totals at Home: Have scored an average of 33.40 pts and allowed 10.50 pts in the last 10 home games
NCAAF Standings Select Season
| Big Ten | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Indiana
|
4 | 0 | 219 | 33 | 186 | 4-0 | 0-0 | 4W |
Maryland
|
4 | 0 | 130 | 43 | 87 | 3-0 | 1-0 | 4W |
Ohio State
|
3 | 0 | 121 | 16 | 105 | 3-0 | 0-0 | 3W |
|
Oregon
|
4 | 0 | 203 | 37 | 166 | 3-0 | 1-0 | 4W |
|
Penn State
|
3 | 0 | 132 | 17 | 115 | 3-0 | 0-0 | 3W |
USC
|
4 | 0 | 210 | 81 | 129 | 3-0 | 1-0 | 4W |
Washington
|
3 | 0 | 167 | 55 | 112 | 2-0 | 1-0 | 3W |
Rutgers
|
3 | 1 | 167 | 96 | 71 | 3-1 | 0-0 | 1L |
Nebraska
|
3 | 1 | 174 | 54 | 120 | 2-1 | 1-0 | 1L |
Michigan State
|
3 | 1 | 137 | 115 | 22 | 3-0 | 0-1 | 1L |
Michigan
|
3 | 1 | 140 | 71 | 69 | 2-0 | 1-1 | 2W |
Iowa
|
3 | 1 | 132 | 58 | 74 | 2-0 | 1-1 | 2W |
Illinois
|
3 | 1 | 145 | 85 | 60 | 2-0 | 1-1 | 1L |
Minnesota
|
2 | 1 | 103 | 37 | 66 | 2-0 | 0-1 | 1L |
Purdue
|
2 | 2 | 112 | 106 | 6 | 2-1 | 0-1 | 2L |
Wisconsin
|
2 | 2 | 83 | 75 | 8 | 2-1 | 0-1 | 2L |
Northwestern
|
1 | 2 | 59 | 64 | -5 | 1-1 | 0-1 | 1L |
UCLA
|
0 | 3 | 43 | 108 | -65 | 0-2 | 0-1 | 3L |
Florida State
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