Pittsburgh vs East Carolina Prediction, Picks & Odds | 27 Dec 2025
College Football Betting Preview: Pitt Panthers vs East Carolina
Pitt Panthers square off against East Carolina at Navy Marine Corps Memorial Stadium, with kickoff scheduled for 11:00 on Saturday, December 27.
East Carolina look capable of avoiding a big loss against Pitt Panthers and we’re happy to bet the underdogs against the spread. They can comfortably cover +10.5 and this can be backed at -118.
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Pittsburgh Panthers have triumphed in four straight road games. Their previous contest was a 38-7 home defeat against Miami Hurricanes at Acrisure Stadium.
East Carolina Pirates have now achieved four straight home wins. In their last game, they won on the road at FAU Football Stadium when beating Florida Atlantic Owls 42-3.
Pittsburgh vs East Carolina Prediction & Picks
Get fully prepped for Pittsburgh vs East Carolina with our betting guide, featuring our expert match pick, predicted scoreline and a value-focused bet builder. Read on for the full breakdown.
Game Prediction
We like the look of East Carolina +10.5 at odds of -118. We think they can take on the market leaders and put up a strong showing in this college football showdown.
It’s important to know which players are unavailable for the upcoming action along with the current form of each team. If you're after stats, you're in the right place because they form the foundation of our CFB predictions.
Key Pittsburgh vs East Carolina stats:
East Carolina +10.5 Probability
If you go by the top betting apps, there’s a 54.1% chance that our pick is settled as a winner. However, we think that the probability is close to 60% taking all factors into consideration. This college wager can therefore be backed with confidence.
In the quest to secure bigger odds, there’s the possibility of moving the line. There are plenty of choices when it comes to doing this, so you can choose the option that suits you.
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Same Game Parlay Picks
Our same game parlay pick is East Carolina +10.5 on the spread, Over 52.5 and the first score to be a Touchdown.
A same game parlay is a fantastic option for bettors who want to focus their wagering on a single football game. You can predict different outcomes and see their odds combined before going ahead and placing this tailored bet.
Correct Score Prediction
34
-
28
East Carolina
If you want to take a chance on a correct score, then Pittsburgh to achieve a 34-28 win could be along the right lines. There are huge odds for this particular outcome.
Pittsburgh vs East Carolina Odds
The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.
The sportsbooks have Pittsburgh at -357 when it comes to the Moneyline betting, implying the market leaders are 78% likely to win this college game according to the latest odds. The market suggests that East Carolina are least likely to win at +285.
The current spread is 10.5 and total points is 52.5. The beauty of the Totals is that you only have to choose from one of two options. If you want to back Over 52.5, it’s -115.
The good news is that you can access a wide range of team props and game lines for most college football clashes. The top betting sites offer a great selection of pre-game and in-game wagering options.
Should you be more interested in a specific individual who is competing, check out the gambling sites’ prop bets where you can pick out player and quarterback lines that focus on performance rather than the game result.
For those looking to enjoy a thrilling in-game wager, then college football micro betting could be up your street. You are now able to wager on what will happen on the next snap by staking your money on the Next Play Result.
Latest regular season and playoff games stats.
Pittsburgh Stats
East Carolina Pirates Stats
- 6 wins and 4 defeats in the last 10 games
- 5 wins and 5 defeats in the last 10 games on the road
- -10.5 Betting Line: Have covered the spread in 5 of the last 10 games
- -10.5 Betting Line on the Road: Have covered the spread in 3 of the last 10 games on the road
- +10.5 Betting Line: Have covered the spread in 8 of the last 10 games
- +10.5 Betting Line at Home: Have covered the spread in 8 of the last 10 home games
- Game Totals: An average of 58.80 pts in the previous 10 games
- Game Totals on the Road: An average of 61.60 pts in the previous 10 games on the road
- Over 52.5: Covered in 7 of the previous 10 games
- Over 52.5 on the Road: Covered in 8 of the previous 10 games on the road
- Team Totals: Have scored an average of 31.50 pts and allowed 27.30 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 30.20 pts and allowed 31.40 pts in the last 10 games on the road
- Game Totals: An average of 54.60 pts in the previous 10 games
- Game Totals at Home: An average of 59.30 pts in the previous 10 home games
- Over 52.5: Covered in 5 of the previous 10 games
- Over 52.5 at Home: Covered in 7 of the previous 10 home games
- Team Totals: Have scored an average of 32.90 pts and allowed 21.70 pts in the last 10 games
- Team Totals at Home: Have scored an average of 37.20 pts and allowed 22.10 pts in the last 10 home games
| American Athletic | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Tulane
|
11 | 2 | 378 | 294 | 84 | 7-0 | 4-2 | 5W |
North Texas
|
11 | 2 | 582 | 324 | 258 | 6-1 | 5-1 | 1L |
Navy
|
10 | 2 | 374 | 312 | 62 | 7-0 | 3-2 | 3W |
South Florida
|
9 | 3 | 516 | 280 | 236 | 6-0 | 3-3 | 2W |
|
East Carolina
|
8 | 4 | 402 | 244 | 158 | 5-1 | 3-3 | 1W |
Memphis
|
8 | 4 | 415 | 270 | 145 | 4-2 | 4-2 | 3L |
Army
|
6 | 6 | 269 | 265 | 4 | 2-3 | 4-3 | 1L |
UTSA
|
6 | 6 | 405 | 355 | 50 | 4-2 | 2-4 | 1L |
Temple
|
5 | 7 | 334 | 356 | -22 | 2-4 | 3-3 | 4L |
Rice
|
5 | 7 | 238 | 387 | -149 | 3-4 | 2-3 | 2L |
Florida Atlantic
|
4 | 8 | 354 | 436 | -82 | 3-3 | 1-5 | 3L |
UAB
|
4 | 8 | 317 | 459 | -142 | 3-3 | 1-5 | 1W |
Tulsa
|
4 | 8 | 278 | 347 | -69 | 2-4 | 2-4 | 1L |
Charlotte
|
1 | 11 | 172 | 436 | -264 | 1-6 | 0-5 | 9L |
| Atlantic Coast | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Miami
|
10 | 2 | 409 | 166 | 243 | 7-1 | 3-1 | 4W |
Virginia
|
10 | 3 | 418 | 267 | 151 | 6-2 | 4-1 | 1L |
Georgia Tech
|
9 | 3 | 397 | 300 | 97 | 5-2 | 4-1 | 2L |
|
Pittsburgh
|
8 | 4 | 421 | 299 | 122 | 4-3 | 4-1 | 1L |
SMU
|
8 | 4 | 395 | 248 | 147 | 5-1 | 3-3 | 1L |
Louisville
|
8 | 4 | 362 | 253 | 109 | 5-3 | 3-1 | 1W |
Wake Forest
|
8 | 4 | 322 | 258 | 64 | 5-2 | 3-2 | 1L |
Duke
|
8 | 5 | 442 | 373 | 69 | 3-3 | 5-2 | 3W |
NC State
|
7 | 5 | 362 | 346 | 16 | 6-1 | 1-4 | 2W |
California
|
7 | 5 | 298 | 318 | -20 | 4-2 | 3-3 | 1W |
Clemson
|
7 | 5 | 344 | 245 | 99 | 3-4 | 4-1 | 4W |
Florida State
|
5 | 7 | 396 | 264 | 132 | 5-2 | 0-5 | 2L |
Stanford
|
4 | 8 | 226 | 350 | -124 | 4-2 | 0-6 | 1L |
North Carolina
|
4 | 8 | 231 | 294 | -63 | 2-4 | 2-4 | 3L |
Virginia Tech
|
3 | 9 | 257 | 362 | -105 | 2-5 | 1-4 | 4L |
Syracuse
|
3 | 9 | 242 | 419 | -177 | 2-4 | 1-5 | 8L |
Boston College
|
2 | 10 | 305 | 393 | -88 | 1-6 | 1-4 | 1W |
Central Michigan
Northwestern
New Mexico
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UTSA
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