South Carolina vs LSU Prediction, Picks & Odds | 11 Oct 2025
College Football Betting Preview: South Carolina vs LSU
South Carolina face LSU in this NCAAF Week 7 battle at Tiger Stadium, with kickoff scheduled for 19:45 on Saturday 11 October. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.
LSU Can Cover the Line
It’s time to go for LSU against the spread, especially with an attractive -8.5 line at -110. Our prediction is that this can be comfortably achieved when playing South Carolina.
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36-33 Win for LSU in Pair’s Previous Matchup
South Carolina Gamecocks won their previous game, beating Kentucky Wildcats at home. It was a 35-13 win at Williams-Brice Stadium.
LSU Tigers have won three consecutive games at home. In their last appearance, they suffered a 24-19 road defeat against Ole Miss at Vaught-Hemingway Stadium.
Head-to-Head Statistics
LSU had the edge in the most recent matchup between these teams. At Williams-Brice Stadium, they recorded a 36-33 win over South Carolina.
Quarterbacks
LaNorris Sellers
Garrett Nussmeier
South Carolina vs LSU Prediction & Picks
This South Carolina vs LSU betting guide features sharp analysis across major markets, including a match prediction, correct score bet, valuable player prop picks and a strategic bet builder.
Game Prediction
LSU are available at odds of -110 when it comes to backing them against the spread in this college football battle. The -8.5 line could be covered with ease by the favorites and this looks like a value bet.
Our CFB predictions are built after tracking the latest team news and reviewing recent form. We also dive into stats, which often serve as a solid barometer for how the action might unfold.
Key South Carolina vs LSU stats:
LSU -8.5 Probability
If you go by the top betting apps, there’s a 52.4% chance that our pick is settled as a winner. However, we have this figure between 55-60% based on our in-depth research. That means we are regarding it as a value wager.
In the hunt for bigger odds, you might be interested to know that you can move the line. This allows you to shoot for a team to perform better than expected by the sportsbooks.
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Best Bet
LSU -8.5 @ -110
Player Prop Picks
You can place a bet on Garrett Nussmeier (LSU) at -114 to go over 265.5 passing yards. The line for QB Passing Yards looks attractive and we’re confident of securing a return.
Nyck Harbor (South Carolina) is priced at -114 to rack up over 40.5 receiving yards. The line for Player Receiving Yards looks attractive and we’re confident of securing a return.
Same Game Parlay Picks
Our same game parlay pick is LSU -8.5 on the spread, Under 44.5 and Garrett Nussmeier (LSU) to have Over 265.5 passing yards.
The same game parlay option is fantastic for football bettors wanting a personalised multi-leg wager on the same game. It’s especially good if you have a strong opinion on the likely outcomes and the odds for each selection are combined.
Correct Score Prediction
14
-
24
LSU
Rather than backing LSU to triumph, there’s the alternative to try your luck when it comes to the correct score lines. Take a chance on a 24-14 win in their favor.
South Carolina vs LSU Odds
The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.
LSU Heavy Favorites to Win
With the sportsbooks giving them a 77% probability of winning this college game, LSU might be a popular parlay pick. That is reflected in their -333 Moneyline betting odds. The market suggests that South Carolina are least likely to win at +265.
The spread currently stands at 9.5 and the total points line is 44.5. There is no denying the popularity of wagering on the Totals. If you’re going for Under 44.5, this outcome can be backed at -115.
College football bettors are spoilt for choice thanks to the huge selection of team props and game lines which are available for every matchup on the coupon. Head to the top sportsbooks and find the best value wagers.
Caden Durham Favorite to Be First TD Scorer
Those interested in favorite Caden Durham to score the first touchdown are able to get +420. If the Anytime TD angle makes appeal, then this is -164.
Touchdown
Receiving Yards
Rushing Yards
Passing Yards
LSU Keep Piling Up Home Wins
LSU have stacked up five straight victories at Tiger Stadium. They have nine wins and one loss in the last 10 home games, averaging 32.20 points on offense and surrendering 17.70 on defense.
South Carolina have four wins and six losses in the last 10 road games, averaging 22.20 points on offense and surrendering 21.80 on defense.
The last time these teams met at Tiger Stadium, LSU came out on top 52-24 against South Carolina.
| Last 10 Games | W-L | P | PF | PA | O44.5 | U44.5 | |
|---|---|---|---|---|---|---|---|
 LSU Home Stats |
9-1 | 49.90 | 32.20 | 17.70 | 7 | 3 | |
 South Carolina Away Stats |
4-6 | 44.00 | 22.20 | 21.80 | 5 | 5 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O44.5 = Games Over 44.5 Points
- U44.5 = Games Under 44.5 Points
Last 5 & H2H
Latest regular season and playoff games stats.
South Carolina Gamecocks Stats
LSU Tigers Stats
- 7 wins and 3 defeats in the last 10 games
- 4 wins and 6 defeats in the last 10 games on the road
- +8.5 Betting Line: Have covered the spread in 8 of the last 10 games
- +8.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road
- -8.5 Betting Line: Have covered the spread in 5 of the last 10 games
- -8.5 Betting Line at Home: Have covered the spread in 7 of the last 10 home games
- Game Totals: An average of 45.40 pts in the previous 10 games
- Game Totals on the Road: An average of 44.00 pts in the previous 10 games on the road
- Over 44.5: Covered in 5 of the previous 10 games
- Over 44.5 on the Road: Covered in 5 of the previous 10 games on the road
- Team Totals: Have scored an average of 27.60 pts and allowed 17.80 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 22.20 pts and allowed 21.80 pts in the last 10 games on the road
- Game Totals: An average of 46.40 pts in the previous 10 games
- Game Totals at Home: An average of 50.90 pts in the previous 10 home games
- Over 44.5: Covered in 4 of the previous 10 games
- Over 44.5 at Home: Covered in 7 of the previous 10 home games
- Team Totals: Have scored an average of 26.90 pts and allowed 19.50 pts in the last 10 games
- Team Totals at Home: Have scored an average of 32.20 pts and allowed 18.70 pts in the last 10 home games
NCAAF Standings Select Season
| Southeastern | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Missouri
|
5 | 0 | 226 | 73 | 153 | 5-0 | 0-0 | 5W |
Oklahoma
|
5 | 0 | 169 | 36 | 133 | 4-0 | 1-0 | 5W |
Ole Miss
|
5 | 0 | 203 | 94 | 109 | 4-0 | 1-0 | 5W |
Texas A&M
|
5 | 0 | 174 | 105 | 69 | 4-0 | 1-0 | 5W |
Vanderbilt
|
5 | 1 | 259 | 116 | 143 | 3-0 | 2-1 | 1L |
Alabama
|
4 | 1 | 182 | 80 | 102 | 3-0 | 1-1 | 4W |
Georgia
|
4 | 1 | 173 | 92 | 81 | 3-1 | 1-0 | 1W |
|
LSU
|
4 | 1 | 135 | 61 | 74 | 3-0 | 1-1 | 1L |
Tennessee
|
4 | 1 | 255 | 145 | 110 | 3-1 | 1-0 | 2W |
Mississippi State
|
4 | 2 | 202 | 119 | 83 | 3-1 | 1-1 | 2L |
Auburn
|
3 | 2 | 138 | 82 | 56 | 2-0 | 1-2 | 2L |
|
South Carolina
|
3 | 2 | 124 | 94 | 30 | 3-1 | 0-1 | 1W |
Texas
|
3 | 2 | 148 | 60 | 88 | 3-0 | 0-2 | 1L |
Arkansas
|
2 | 3 | 187 | 150 | 37 | 2-1 | 0-2 | 3L |
Florida
|
2 | 3 | 117 | 85 | 32 | 2-1 | 0-2 | 1W |
Kentucky
|
2 | 3 | 122 | 139 | -17 | 2-1 | 0-2 | 2L |
South Florida
North Texas
Betting Tips
21:00 - Fri 10 Oct
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12:00 - Sat 11 Oct
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13:00 - Sat 11 Oct
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