Stanford vs Virginia Prediction, Picks & Odds | 20 Sep 2025
College Football Betting Preview: Stanford vs Virginia
Stanford square off against Virginia in this NCAAF Week 4 matchup at Scott Stadium, with kickoff scheduled for 19:30 on Saturday, September 20. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.
We’d be surprised if Virginia don’t exceed a -15.5 spread against Stanford. That is why the bet has to be for them to cover the line at -115.
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Stanford Cardinal have lost their previous two on the road. Their most recent game was at home at Stanford Stadium where they recorded a 30-20 victory over Boston College Eagles.
Virginia Cavaliers won their last game 55-16, making it back-to-back home wins. This was recorded at Scott Stadium against William & Mary Tribe.
Stanford vs Virginia Prediction & Picks
This Stanford vs Virginia betting breakdown features a main match prediction, a correct score insight and a sharply constructed bet builder to guide your wagers.
Game Prediction
Our pick is that Virginia will get the better of their opponents by a significant margin in this college football matchup. With this in mind, let’s go for the favorites at -15.5 on the spread which is currently available at odds of -115.
Incoming team news often impacts the betting lines and odds in significant ways. Our college football handicappers factor this in alongside recent form, while key stats are also carefully weighed to strengthen each pick.
Key Stanford vs Virginia stats:
UVA -15.5 Probability
According to the best betting apps, our pick has a 53.5% chance of winning. Taking all factors into consideration, our cappers think there’s a stronger chance of success and estimate the probability to be closer to 60%. It's why we think it’s worth placing this college wager.
If you want to land a big potential return from a small stake, then a Bet Builder could be a good way to go. Back Virginia against the spread in a combination with other picks.
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Same Game Parlay Picks
Try out our same game parlay pick which starts with Virginia -15.5. We’ve also gone for Over 48.5 points and Field Goal as first scoring play.
We recommend a same game parlay as it’s a great way of betting on a single event. Many football bettors like to create a personalised wager which reflects their predictions for how a game is going to play out.
Correct Score Prediction
17
-
38
Virginia
There’s the chance to land massive odds when it comes to a Virginia correct score win. We’ll try a 38-17 victory in their favor and this should be in the right ball park.
Stanford vs Virginia Odds
The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.
Virginia have short betting odds and they’re overwhelming -769 favorites for this college game. This means the sportsbooks give them a 88% chance of winning. The market suggests that Stanford are least likely to win at +520.
The spread currently stands at 16.5 and the total points line is 48.5. Having a bet on the Totals is one of the most popular football wagers. Those expecting a low total can back Under 48.5 at -110.
The top sportsbooks offer a huge selection of team props and game lines when it comes to most college football games. Make sure you look through all the available options before deciding which bet to place.
We’re fond of the quarterback and player props as an alternative to betting on the game lines. The gambling sites will have Player Kicking Points, Longest Rushing Attempt and Rushing Yards among the choices and you can take a view.
Micro betting is something that’s really popular with bettors, with college football fans essentially being able to wager in-game when it comes to score, player and team props. Sometimes these are two-way lines where you can bet on the Next Play or Next Drive.
Virginia With Five Wins in Past Ten Home Games
Virginia own a 5-5 mark in their past 10 home games, putting up 26.20 points per contest and giving up 25.70.
Stanford have suffered seven consecutive road defeats. They have gone 2-8 across their last 10 road games, posting 17.70 points per contest while yielding 34.90.
| Last 10 Games | W-L | P | PF | PA | O48.5 | U48.5 | |
|---|---|---|---|---|---|---|---|
 Virginia Home Stats |
5-5 | 51.90 | 26.20 | 25.70 | 5 | 5 | |
 Stanford Away Stats |
2-8 | 52.60 | 17.70 | 34.90 | 6 | 4 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O48.5 = Games Over 48.5 Points
- U48.5 = Games Under 48.5 Points
Latest regular season and playoff games stats.
Stanford Cardinal Stats
Virginia Cavaliers Stats
- 2 wins and 8 defeats in the last 10 games
- 2 wins and 8 defeats in the last 10 games on the road
- +15.5 Betting Line: Have covered the spread in 6 of the last 10 games
- +15.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road
- -15.5 Betting Line: Have covered the spread in 2 of the last 10 games
- -15.5 Betting Line at Home: Have covered the spread in 3 of the last 10 home games
- Game Totals: An average of 55.00 pts in the previous 10 games
- Game Totals on the Road: An average of 52.60 pts in the previous 10 games on the road
- Over 48.5: Covered in 7 of the previous 10 games
- Over 48.5 on the Road: Covered in 6 of the previous 10 games on the road
- Team Totals: Have scored an average of 21.20 pts and allowed 33.80 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 17.70 pts and allowed 34.90 pts in the last 10 games on the road
- Game Totals: An average of 55.60 pts in the previous 10 games
- Game Totals at Home: An average of 51.90 pts in the previous 10 home games
- Over 48.5: Covered in 7 of the previous 10 games
- Over 48.5 at Home: Covered in 5 of the previous 10 home games
- Team Totals: Have scored an average of 26.10 pts and allowed 29.50 pts in the last 10 games
- Team Totals at Home: Have scored an average of 26.20 pts and allowed 25.70 pts in the last 10 home games
| Atlantic Coast | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
|
Virginia
|
10 | 2 | 398 | 240 | 158 | 6-1 | 4-1 | 2W |
Miami
|
10 | 2 | 409 | 166 | 243 | 7-1 | 3-1 | 4W |
Georgia Tech
|
9 | 3 | 397 | 300 | 97 | 5-2 | 4-1 | 2L |
Pittsburgh
|
8 | 4 | 421 | 299 | 122 | 4-3 | 4-1 | 1L |
SMU
|
8 | 4 | 395 | 248 | 147 | 5-1 | 3-3 | 1L |
Louisville
|
8 | 4 | 362 | 253 | 109 | 5-3 | 3-1 | 1W |
Wake Forest
|
8 | 4 | 322 | 258 | 64 | 5-2 | 3-2 | 1L |
Duke
|
7 | 5 | 415 | 353 | 62 | 3-3 | 4-2 | 2W |
NC State
|
7 | 5 | 362 | 346 | 16 | 6-1 | 1-4 | 2W |
Clemson
|
7 | 5 | 344 | 245 | 99 | 3-4 | 4-1 | 4W |
California
|
7 | 5 | 298 | 318 | -20 | 4-2 | 3-3 | 1W |
Florida State
|
5 | 7 | 396 | 264 | 132 | 5-2 | 0-5 | 2L |
|
Stanford
|
4 | 8 | 226 | 350 | -124 | 4-2 | 0-6 | 1L |
North Carolina
|
4 | 8 | 231 | 294 | -63 | 2-4 | 2-4 | 3L |
Virginia Tech
|
3 | 9 | 257 | 362 | -105 | 2-5 | 1-4 | 4L |
Syracuse
|
3 | 9 | 242 | 419 | -177 | 2-4 | 1-5 | 8L |
Boston College
|
2 | 10 | 305 | 393 | -88 | 1-6 | 1-4 | 1W |
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