UConn vs Syracuse Prediction, Picks & Odds | 06 Sep 2025

College Football Betting Preview: UConn vs Syracuse

UConn face Syracuse in this NCAAF Week 2 matchup at JMA Wireless Dome, with kickoff scheduled for 12:00 on Saturday 6 September. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.

UConn to Give Syracuse a Tough Test

There’s a great opportunity to back UConn against the spread considering they should perform well against Syracuse. Snap up the -106 when it comes to the underdogs covering the +6.5.

Feeling good about our ATS pick? Grab the best BetMGM promo code and check out our comprehensive site review before you jump in.

Syracuse Too Strong for UConn in Last H2H

UConn Huskies claimed a victory in their previous game. A 59-13 home win occurred against Central Connecticut State Blue Devils at Rentschler Field.

Syracuse Orange were defeated in their last game. They suffered a 45-26 reverse against Tennessee Volunteers at Mercedes-Benz Stadium.

Head-to-Head Statistics

Syracuse triumphed 31-24 when they last played UConn. This head-to-head was played at JMA Wireless Dome.

UConn vs Syracuse Prediction & Picks

Make the most of UConn vs Syracuse with our betting analysis that includes an expert match prediction, expected scoreline and a hand-picked bet builder designed for value.

Game Prediction

There’s the opportunity to back UConn to cover the +6.5 line in this college football battle. Betting the underdogs on the spread seems the logical play and there is -106 now available.

We’re always on top of team news and when combined with recent form, it helps us uncover the best value. Our college football handicappers also take a data-led approach, using key stats to back every pick.

Key UConn vs Syracuse stats:

• The +6.5 line has been covered by UConn in 9 of their last 10 games.
• The +6.5 line has been covered by UConn in 4 of their last 5 games.
• The +6.5 line has been covered by UConn in 3 consecutive games.
• The -6.5 line hasn’t been covered by Syracuse in 12 of their last 20 games.

UConn +6.5 Probability

Based on the odds from the top betting apps, our pick has a 51.5% chance of landing a return. In the opinion of our cappers, there’s actually a probability of success closer to 60%. It’s why we think it’s worth placing this college bet.

In the hunt for tastier odds, you might be interested to know that you can move the betting line. This allows you to shoot for a team to perform better than expected by the sportsbooks.

Our user-friendly bonus guide highlights the newest betting offers, free bets, and sign-up deals in one spot.

Best Bet

UConn +6.5 @ -106 Bet Now

BetMGM Promo Up To $1500 in Bonus Bets Get Bonus T&C apply. Gamble responsibly 18+

Gamble responsibly 18+. All odds are correct at time of publishing and are subject to change. To use the Bookmaker Live Streaming services you will need to be logged in and have a funded account or to have placed a bet in the last 24 hours. Geo-restrictions apply.

Correct Score Prediction

UConn 30 - 31 Syracuse

Syracuse are available at massive odds to register a 31-30 victory and they might have the edge. This should be a close matchup and there won’t be much between the teams.

UConn vs Syracuse Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Books Think Syracuse Likeliest to Win

Syracuse are regarded as having a 72% chance of winning this college game according to the latest betting odds. The sportsbooks have priced them up at -256. For those wanting to oppose the market leader, you can get +205 about UConn.

The current spread is 6.5 and the total points line is 57.5. A Total bet relates to the number of points that will be scored overall. If you’re going for Under 57.5, this outcome can be backed at -110.

The good news is that you can access a wide range of team props and game lines for most college football clashes. The top betting sites offer a great selection of pre-game and in-game wagering options.

Moneyline

UConn

+205

Syracuse

-256

Point Spread

UConn +6.5

-100

Syracuse -6.5

-122

Total Points

Under 57.5

-110

Over 57.5

-110

Player Props & Micro Betting

There is regularly value to be found from betting the quarterback and player props with the best online gambling sites. You can find lots of ways to back for or against a specific player lining up for one of the two teams.

It’s possible to use stats to your advantage when it comes to college football micro betting, especially if you’re predicting outcomes such as the Next Drive Result. Check out the live player, score and team props and see if you can find an angle.

Syracuse Keep Cashing In at Home

Syracuse have stacked up four straight victories at JMA Wireless Dome. They are 8-2 in their last 10 home games, averaging 30.90 points scored and 27.20 points allowed.

UConn have four wins and six losses in the last 10 games on the road, averaging 21.10 points scored and 32.80 points allowed.

Syracuse earned a 31-24 win against UConn in the teams’ last meeting at JMA Wireless Dome.

Last 10 Games		W-L	P	PF	PA	O58.5	U58.5
Syracuse Home Stats		8-2	58.10	30.90	27.20	5	5
UConn Away Stats		4-6	53.90	21.10	32.80	2	8

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O58.5 = Games Over 58.5 Points
• U58.5 = Games Under 58.5 Points

Last 5 & H2H

Latest regular season and playoff games stats.

UConn Stats

Syracuse Orange Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 4 wins and 6 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 home games

Point Spread

• +6.5 Betting Line: Have covered the spread in 9 of the last 10 games
• +6.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• -6.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -6.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games

Total Points

• Game Totals: An average of 54.10 pts in the previous 10 games
• Game Totals on the Road: An average of 53.90 pts in the previous 10 games on the road
• Over 58.5: Covered in 3 of the previous 10 games
• Over 58.5 on the Road: Covered in 2 of the previous 10 games on the road
• Team Totals: Have scored an average of 33.50 pts and allowed 20.60 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 21.10 pts and allowed 32.80 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 66.80 pts in the previous 10 games
• Game Totals at Home: An average of 58.10 pts in the previous 10 home games
• Over 58.5: Covered in 6 of the previous 10 games
• Over 58.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 33.40 pts and allowed 33.40 pts in the last 10 games
• Team Totals at Home: Have scored an average of 30.90 pts and allowed 27.20 pts in the last 10 home games

NCAAF Standings Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	W	L	PF	PA	N. Pts	Home	Away	Strk
Boston College	1	0	66	10	56	1-0	0-0	1W
NC State	1	0	24	17	7	1-0	0-0	1W
Wake Forest	1	0	10	9	1	1-0	0-0	1W
Virginia	1	0	48	7	41	1-0	0-0	1W
SMU	1	0	42	13	29	1-0	0-0	1W
California	1	0	34	15	19	0-0	1-0	1W
Pittsburgh	1	0	61	9	52	1-0	0-0	1W
Miami	1	0	27	24	3	1-0	0-0	1W
Louisville	1	0	51	17	34	1-0	0-0	1W
Georgia Tech	1	0	27	20	7	0-0	1-0	1W
Florida State	1	0	31	17	14	1-0	0-0	1W
Duke	1	0	45	17	28	1-0	0-0	1W
Clemson	0	1	10	17	-7	0-1	0-0	1L
North Carolina	0	1	14	48	-34	0-1	0-0	1L
Stanford	0	1	20	23	-3	0-0	0-1	1L
Syracuse	0	1	26	45	-19	0-0	0-1	1L
Virginia Tech	0	1	11	24	-13	0-0	0-1	1L

Independents I-A	W	L	PF	PA	N. Pts	Home	Away	Strk
UConn	1	0	59	13	46	1-0	0-0	1W
Notre Dame	0	1	24	27	-3	0-0	0-1	1L