New England Patriots
American Football NFL Caesars Superdome Sun 12 Oct 13:00
New Orleans Saints
  1. Prediction
  2. SGP Picks
  3. Odds
  4. Player Props
  5. Stats
  6. Live Stream
  7. Team News
  8. Lineups
  9. Injuries
  10. Standings

NFL Betting Preview: Patriots vs Saints

The New England Patriots go up against the New Orleans Saints in this NFL Week 6 matchup at Caesars Superdome, with kickoff scheduled for 13:00 on Sunday 12 October. Our betting preview features expert predictions, picks, updated betting odds, head-to-head stats and the latest team news, including injuries.

Back Patriots For a Convincing Win

We’re confident of backing the Patriots to cover the -3.5 spread when they clash with the Saints. This is a more than generous line and they look a value pick at -105.

Like our read on the spread? Claim the best BetMGM promo code and read our expert review of the site before you decide where to put your money.

Saints 34-0 to the Good in Previous H2H

New England Patriots won their previous game 23-20. This road victory at Highmark Stadium against Buffalo Bills was their second on the spin. The Patriots totaled 338 yards, split between 267 passing and 71 rushing yards. The offense produced 21 first downs and found the end zone twice.

New Orleans Saints were winners last time out. It was a 26-14 home victory against New York Giants at Caesars Superdome. The Saints put up 332 total yards, made up of 244 through the air and 88 on the ground. They picked up 18 first downs to go along with two touchdowns.

Head-to-Head Statistics

The Saints beat the Patriots in their last head-to-head matchup. It was a 34-0 scoreline at Gillette Stadium.

Quarterbacks

Patriots vs Saints Prediction & Picks

Our Patriots vs Saints betting preview covers everything you need, including a key match prediction, correct score insight, top player prop bets and a value-packed bet builder recommendation.

Game Prediction

Get with the betting favorites with a -3.5 spread. We’re backing the Patriots at odds of -105 to enjoy a solid victory in this NFL matchup.

The NFL handicappers at Sportsgambler.com stay on top of injuries and team form that could impact the outcome. We also leave no stone unturned when analyzing the latest stats to support every prediction.

Key Patriots vs Saints stats:

  • The +3.5 line hasn’t been covered by Saints in 4 of their last 5 games this season.
  • The +3.5 line hasn’t been covered by Saints in 7 of their last 10 games.

Patriots -3.5 Probability

When you look at the latest betting odds, our pick has a 51.3% chance of winning. In our opinion, there’s actually a probability of success closer to 60%. It is therefore regarded as a value bet.

Looking for Bigger Odds?

There’s the opportunity to sell points and that means moving the line until you’re happy with the wager. It means a riskier spread bet but a bigger return on the odds available.

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Best Bet

Patriots -3.5 @ -105 Watch Live Bet Now BetMGM logo
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Published 19:26, 10 October 2025

Player Prop Picks

Top Pick: TreVeyon Henderson Anytime TD +125 BetMGM logo

TreVeyon Henderson (Patriots) can be backed at +125 to record a TD. There are appealing odds on offer for this Anytime Touchdown Scorer pick, and we believe it's an attractive wager for him to punch it in.

Latest TreVeyon Henderson Player Prop Odds

Drake Maye Over 22.5 Rushing Yards -118 BetMGM logo

The odds for Drake Maye (Saints) to go over 22.5 rushing yards are -118. With confidence, we can back him to cover the generous Player Rushing Yards line, as all the signs point to him reaching the expected total.

Latest Drake Maye Player Prop Odds

Same Game Parlay Picks

Spread Patriots -3.5
Totals Under 45.5
Anytime Touchdown TreVeyon Henderson

Take a same game parlay that incorporates Patriots to cover the -3.5 spread along with Under 45.5 points. Add in TreVeyon Henderson (Patriots) as an anytime touchdown scorer.

A same game parlay is a fantastic way of cheering on different picks within the same football game. You can predict a number of outcomes and get bigger odds than a single bet. The odds can combine to great effect.

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Correct Score Prediction

Patriots Patriots logo 24 - 13 Saints logo Saints

The Patriots can be wagered in lots of different ways and this includes the correct score lines. There’s the chance to back them to win 24-13 for a big potential return.

Patriots vs Saints Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Books Think Patriots Likeliest to Win

For this game, the sportsbooks’ Moneyline betting odds mean New England Patriots are -185 favorites to win and that means a 65% chance of landing a victory. New Orleans Saints are trading at bigger odds than their opponents and they can be backed at +154.

3.5 is the spread and 45.5 is the total points line. The Totals offers NFL fans an alternative way of getting involved. If you’re going for Under 45.5, this outcome can be backed at -105.

Take a well-rounded approach when placing your bets. The top NFL betting sites are packed with team props and game lines, so focus on finding the selection that reflects your read on the matchup.

Rhamondre Stevenson Favorite to Be First Touchdown Scorer

There is +110 available that Rhamondre Stevenson scores a TD at any stage. He is available at +650 to record the first touchdown which makes him favorite.

Touchdown

Rhamondre Stevenson (Patriots)
First TD
+650
Anytime TD
+110
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Alvin Kamara (Saints)
First TD
+750
Anytime TD
+120
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Kendre Miller (Saints)
First TD
+750
Anytime TD
+120
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TreVeyon Henderson (Patriots)
First TD
+750
Anytime TD
+125
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Receiving Yards

Stefon Diggs (Patriots)
Over 60.5
-114
Under 60.5
-114
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Rashid Shaheed (Saints)
Over 46.5
-114
Under 46.5
-114
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Hunter Henry (Patriots)
Over 40.5
-114
Under 40.5
-114
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Rushing Yards

Rhamondre Stevenson (Patriots)
Over 45.5
-108
Under 45.5
-122
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TreVeyon Henderson (Patriots)
Over 33.5
-114
Under 33.5
-114
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Drake Maye (Patriots)
Over 23.5
-114
Under 23.5
-114
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Passing Yards

Best Betting Offers
Caesars Superdome
Caesars Superdome

Saints Have Seven Losses From Past Ten at Home

The Saints are 3-7 in their last 10 home games, putting up 19.50 points on average and giving up 24.10.

The Patriots are 3-7 in their last 10 road games, averaging 17.70 points scored and 24.40 points allowed.

Last 10 Games W-L P PF PA O45.5 U45.5
Saints logo Saints Home Stats 3-7 43.60 19.50 24.10 3 7
Patriots logo Patriots Away Stats 3-7 42.10 17.70 24.40 4 6
  • W-L = Wins-Losses
  • P = Avg. Points
  • PF = Avg. Points For
  • PA = Avg. Points Against
  • O45.5 = Games Over 45.5 Points
  • U45.5 = Games Under 45.5 Points
Team Stats

Latest regular season and playoff games stats.

New England Patriots logo New England Patriots Stats
New Orleans Saints logo New Orleans Saints Stats
Moneyline
  • 4 wins and 6 defeats in the last 10 games
  • 3 wins and 7 defeats in the last 10 games on the road
Moneyline
  • 2 wins and 8 defeats in the last 10 games
  • 3 wins and 7 defeats in the last 10 home games
Point Spread
Point Spread
Total Points
Total Points
Game Stats
Last 10 Games
Game Stats
Last 10 Games
Last 10 Games on the Road
Last 10 Home Games

Live Streaming

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You’re never short of viewing opportunities. Check out the daily list of sporting events that are being covered through this service.

Team News

New England Patriots @ New Orleans Saints Lineups

New Orleans Saints

Manager:
Kellen Moore

New England Patriots

Manager:
Mike Vrabel

New Orleans Saints Substitutes

New England Patriots Substitutes

New England Patriots Injuries

Type
Name
Info
Marcellas Dial
Knee - ACL
Yasir Durant
Undisclosed
Antonio Gibson
Knee - ACL
Christian Gonzalez
Hamstring
Jaylinn Hawkins
Hamstring
Isaiah Iton
Hip
Anfernee Jennings
Ankle
Brock Lampe
Undisclosed
Lan Larison
Foot
Marte Mapu
Neck
Deneric Prince
Undisclosed
Layden Robinson
Undisclosed
Jaquelin Roy
Undisclosed
Wes Schweitzer
Undisclosed
Keion White
Elbow
Charles Woods
Knee

New Orleans Saints Injuries

Type
Name
Info
Julian Blackmon
Shoulder - Labrum
Vernon Broughton
Hip
Derek Carr
Shoulder
Will Clapp
Foot
Alvin Kamara
Ankle
Tyrann Mathieu
Undisclosed
Bub Means
Lower Leg
Trey Palmer
Ankle
Mason Pline
Upper Body
Ja'Lynn Polk
Shoulder
Ryan Ramczyk
Undisclosed
John Ridgeway
Shoulder
Nick Saldiveri
Knee
Barry Wesley
Undisclosed
Isaac Yiadom
Hamstring
Landon Young
Ankle

Previous New England Patriots Lineups

05 Oct NFL
Patriots 23-20 Bills
28 Sep NFL
Panthers 13-42 Patriots
21 Sep NFL
Steelers 21-14 Patriots
14 Sep NFL
Patriots 33-27 Dolphins
07 Sep NFL
Raiders 20-13 Patriots
05 Jan NFL
Bills 16-23 Patriots
28 Dec NFL
Chargers 40-7 Patriots
22 Dec NFL
Patriots 21-24 Bills
15 Dec NFL
Patriots 17-30 Cardinals
01 Dec NFL
Colts 25-24 Patriots

Previous New Orleans Saints Lineups

05 Oct NFL
Giants 14-26 Saints
28 Sep NFL
Saints 19-31 Bills
21 Sep NFL
Saints 13-44 Seahawks
14 Sep NFL
49ers 26-21 Saints
07 Sep NFL
Cardinals 20-13 Saints
05 Jan NFL
Saints 19-27 Buccaneers
29 Dec NFL
Raiders 25-10 Saints
23 Dec NFL
Saints 0-34 Packers
15 Dec NFL
Commanders 20-19 Saints
08 Dec NFL
Saints 14-11 Giants

NFL Standings Select Season

AFC East W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Bills 4 1 0 0.800 153 113 40 3-1-0 1-0-0 2-1-0 3-1-0 4-1-0 1L
Patriots 3 2 0 0.600 125 101 24 1-2-0 2-0-0 2-0-0 2-2-0 3-2-0 2W
Dolphins 1 4 0 0.200 107 145 -38 1-1-0 0-3-0 1-2-0 1-3-0 1-4-0 1L
Jets 0 5 0 0.000 112 157 -45 0-3-0 0-2-0 0-2-0 0-3-0 0-5-0 5L
AFC North W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Steelers 3 1 0 0.750 96 98 -2 1-1-0 2-0-0 0-0-0 2-0-0 3-1-0 2W
Bengals 2 3 0 0.400 85 156 -71 1-1-0 1-2-0 1-0-0 2-1-0 2-3-0 3L
Ravens 1 4 0 0.200 141 177 -36 1-2-0 0-2-0 1-0-0 1-3-0 1-4-0 3L
Browns 1 4 0 0.200 73 123 -50 1-2-0 0-2-0 0-2-0 0-2-0 1-4-0 2L
AFC South W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Colts 4 1 0 0.800 163 89 74 3-0-0 1-1-0 1-0-0 4-0-0 4-1-0 1W
Jaguars 4 1 0 0.800 127 100 27 3-0-0 1-1-0 1-0-0 2-1-0 4-1-0 3W
Texans 2 3 0 0.400 108 61 47 1-1-0 1-2-0 1-1-0 2-1-0 2-3-0 2W
Titans 1 4 0 0.200 73 141 -68 0-2-0 1-2-0 0-2-0 0-3-0 1-4-0 1W
AFC West W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Chargers 3 2 0 0.600 98 98 0 2-1-0 1-1-0 3-0-0 3-0-0 3-2-0 2L
Broncos 3 2 0 0.600 117 84 33 2-0-0 1-2-0 0-1-0 2-2-0 3-2-0 2W
Chiefs 2 3 0 0.400 125 107 18 1-1-0 1-2-0 0-1-0 1-2-0 2-3-0 1L
Raiders 1 4 0 0.200 83 139 -56 0-2-0 1-2-0 0-1-0 1-2-0 1-4-0 4L
NFC East W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Eagles 4 2 0 0.667 142 143 -1 2-1-0 2-1-0 1-1-0 3-1-0 3-2-0 2L
Commanders 3 2 0 0.600 134 101 33 2-0-0 1-2-0 1-0-0 1-2-0 3-2-0 1W
Cowboys 2 2 1 0.400 151 154 -3 1-0-1 1-2-0 1-1-0 1-2-1 2-2-1 1W
Giants 2 4 0 0.333 121 144 -23 2-1-0 0-3-0 1-2-0 1-3-0 2-3-0 1W
NFC North W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Lions 4 1 0 0.800 174 112 62 2-0-0 2-1-0 1-1-0 1-1-0 4-1-0 4W
Packers 2 1 1 0.500 104 84 20 2-0-0 0-1-1 1-0-0 2-0-1 2-1-1 1D
Vikings 3 2 0 0.600 123 97 26 1-1-0 2-1-0 1-0-0 1-1-0 3-2-0 1W
Bears 2 2 0 0.500 101 117 -16 1-1-0 1-1-0 0-2-0 1-2-0 2-2-0 2W
NFC South W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Buccaneers 4 1 0 0.800 135 132 3 1-1-0 3-0-0 1-0-0 2-1-0 4-1-0 1W
Falcons 2 2 0 0.500 76 86 -10 1-1-0 1-1-0 0-2-0 2-2-0 2-2-0 1W
Panthers 2 3 0 0.400 102 119 -17 2-0-0 0-3-0 1-0-0 1-1-0 2-3-0 1W
Saints 1 4 0 0.200 92 135 -43 1-2-0 0-2-0 0-0-0 1-3-0 1-4-0 1W
NFC West W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
49ers 4 1 0 0.800 106 98 8 1-1-0 3-0-0 3-0-0 4-0-0 4-1-0 1W
Seahawks 3 2 0 0.600 146 105 41 1-2-0 2-0-0 1-1-0 2-2-0 3-2-0 1L
Rams 3 2 0 0.600 123 107 16 2-1-0 1-1-0 0-1-0 0-2-0 3-2-0 1L
Cardinals 2 3 0 0.400 103 96 7 1-2-0 1-1-0 0-2-0 2-2-0 2-3-0 3L
AFC Conference W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Colts 4 1 0 0.800 163 89 74 3-0-0 1-1-0 1-0-0 4-0-0 4-1-0 1W
Bills 4 1 0 0.800 153 113 40 3-1-0 1-0-0 2-1-0 3-1-0 4-1-0 1L
Steelers 3 1 0 0.750 96 98 -2 1-1-0 2-0-0 0-0-0 2-0-0 3-1-0 2W
Chargers 3 2 0 0.600 98 98 0 2-1-0 1-1-0 3-0-0 3-0-0 3-2-0 2L
Jaguars 4 1 0 0.800 127 100 27 3-0-0 1-1-0 1-0-0 2-1-0 4-1-0 3W
Broncos 3 2 0 0.600 117 84 33 2-0-0 1-2-0 0-1-0 2-2-0 3-2-0 2W
Patriots 3 2 0 0.600 125 101 24 1-2-0 2-0-0 2-0-0 2-2-0 3-2-0 2W
Bengals 2 3 0 0.400 85 156 -71 1-1-0 1-2-0 1-0-0 2-1-0 2-3-0 3L
Texans 2 3 0 0.400 108 61 47 1-1-0 1-2-0 1-1-0 2-1-0 2-3-0 2W
Chiefs 2 3 0 0.400 125 107 18 1-1-0 1-2-0 0-1-0 1-2-0 2-3-0 1L
Raiders 1 4 0 0.200 83 139 -56 0-2-0 1-2-0 0-1-0 1-2-0 1-4-0 4L
Ravens 1 4 0 0.200 141 177 -36 1-2-0 0-2-0 1-0-0 1-3-0 1-4-0 3L
Dolphins 1 4 0 0.200 107 145 -38 1-1-0 0-3-0 1-2-0 1-3-0 1-4-0 1L
Browns 1 4 0 0.200 73 123 -50 1-2-0 0-2-0 0-2-0 0-2-0 1-4-0 2L
Titans 1 4 0 0.200 73 141 -68 0-2-0 1-2-0 0-2-0 0-3-0 1-4-0 1W
Jets 0 5 0 0.000 112 157 -45 0-3-0 0-2-0 0-2-0 0-3-0 0-5-0 5L
NFC Conference W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Eagles 4 2 0 0.667 142 143 -1 2-1-0 2-1-0 1-1-0 3-1-0 3-2-0 2L
49ers 4 1 0 0.800 106 98 8 1-1-0 3-0-0 3-0-0 4-0-0 4-1-0 1W
Buccaneers 4 1 0 0.800 135 132 3 1-1-0 3-0-0 1-0-0 2-1-0 4-1-0 1W
Lions 4 1 0 0.800 174 112 62 2-0-0 2-1-0 1-1-0 1-1-0 4-1-0 4W
Packers 2 1 1 0.500 104 84 20 2-0-0 0-1-1 1-0-0 2-0-1 2-1-1 1D
Seahawks 3 2 0 0.600 146 105 41 1-2-0 2-0-0 1-1-0 2-2-0 3-2-0 1L
Vikings 3 2 0 0.600 123 97 26 1-1-0 2-1-0 1-0-0 1-1-0 3-2-0 1W
Commanders 3 2 0 0.600 134 101 33 2-0-0 1-2-0 1-0-0 1-2-0 3-2-0 1W
Rams 3 2 0 0.600 123 107 16 2-1-0 1-1-0 0-1-0 0-2-0 3-2-0 1L
Falcons 2 2 0 0.500 76 86 -10 1-1-0 1-1-0 0-2-0 2-2-0 2-2-0 1W
Bears 2 2 0 0.500 101 117 -16 1-1-0 1-1-0 0-2-0 1-2-0 2-2-0 2W
Cowboys 2 2 1 0.400 151 154 -3 1-0-1 1-2-0 1-1-0 1-2-1 2-2-1 1W
Cardinals 2 3 0 0.400 103 96 7 1-2-0 1-1-0 0-2-0 2-2-0 2-3-0 3L
Panthers 2 3 0 0.400 102 119 -17 2-0-0 0-3-0 1-0-0 1-1-0 2-3-0 1W
Saints 1 4 0 0.200 92 135 -43 1-2-0 0-2-0 0-0-0 1-3-0 1-4-0 1W
Giants 2 4 0 0.333 121 144 -23 2-1-0 0-3-0 1-2-0 1-3-0 2-3-0 1W
NFL Team W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Bills 4 1 0 0.800 153 113 40 3-1-0 1-0-0 2-1-0 3-1-0 4-1-0 1L
Lions 4 1 0 0.800 174 112 62 2-0-0 2-1-0 1-1-0 1-1-0 4-1-0 4W
Colts 4 1 0 0.800 163 89 74 3-0-0 1-1-0 1-0-0 4-0-0 4-1-0 1W
Jaguars 4 1 0 0.800 127 100 27 3-0-0 1-1-0 1-0-0 2-1-0 4-1-0 3W
49ers 4 1 0 0.800 106 98 8 1-1-0 3-0-0 3-0-0 4-0-0 4-1-0 1W
Buccaneers 4 1 0 0.800 135 132 3 1-1-0 3-0-0 1-0-0 2-1-0 4-1-0 1W
Steelers 3 1 0 0.750 96 98 -2 1-1-0 2-0-0 0-0-0 2-0-0 3-1-0 2W
Eagles 4 2 0 0.667 142 143 -1 2-1-0 2-1-0 1-1-0 3-1-0 3-2-0 2L
Packers 2 1 1 0.500 104 84 20 2-0-0 0-1-1 1-0-0 2-0-1 2-1-1 1D
Broncos 3 2 0 0.600 117 84 33 2-0-0 1-2-0 0-1-0 2-2-0 3-2-0 2W
Chargers 3 2 0 0.600 98 98 0 2-1-0 1-1-0 3-0-0 3-0-0 3-2-0 2L
Rams 3 2 0 0.600 123 107 16 2-1-0 1-1-0 0-1-0 0-2-0 3-2-0 1L
Vikings 3 2 0 0.600 123 97 26 1-1-0 2-1-0 1-0-0 1-1-0 3-2-0 1W
Patriots 3 2 0 0.600 125 101 24 1-2-0 2-0-0 2-0-0 2-2-0 3-2-0 2W
Seahawks 3 2 0 0.600 146 105 41 1-2-0 2-0-0 1-1-0 2-2-0 3-2-0 1L
Commanders 3 2 0 0.600 134 101 33 2-0-0 1-2-0 1-0-0 1-2-0 3-2-0 1W
Falcons 2 2 0 0.500 76 86 -10 1-1-0 1-1-0 0-2-0 2-2-0 2-2-0 1W
Bears 2 2 0 0.500 101 117 -16 1-1-0 1-1-0 0-2-0 1-2-0 2-2-0 2W
Cowboys 2 2 1 0.400 151 154 -3 1-0-1 1-2-0 1-1-0 1-2-1 2-2-1 1W
Cardinals 2 3 0 0.400 103 96 7 1-2-0 1-1-0 0-2-0 2-2-0 2-3-0 3L
Panthers 2 3 0 0.400 102 119 -17 2-0-0 0-3-0 1-0-0 1-1-0 2-3-0 1W
Bengals 2 3 0 0.400 85 156 -71 1-1-0 1-2-0 1-0-0 2-1-0 2-3-0 3L
Texans 2 3 0 0.400 108 61 47 1-1-0 1-2-0 1-1-0 2-1-0 2-3-0 2W
Chiefs 2 3 0 0.400 125 107 18 1-1-0 1-2-0 0-1-0 1-2-0 2-3-0 1L
Giants 2 4 0 0.333 121 144 -23 2-1-0 0-3-0 1-2-0 1-3-0 2-3-0 1W
Ravens 1 4 0 0.200 141 177 -36 1-2-0 0-2-0 1-0-0 1-3-0 1-4-0 3L
Browns 1 4 0 0.200 73 123 -50 1-2-0 0-2-0 0-2-0 0-2-0 1-4-0 2L
Raiders 1 4 0 0.200 83 139 -56 0-2-0 1-2-0 0-1-0 1-2-0 1-4-0 4L
Dolphins 1 4 0 0.200 107 145 -38 1-1-0 0-3-0 1-2-0 1-3-0 1-4-0 1L
Saints 1 4 0 0.200 92 135 -43 1-2-0 0-2-0 0-0-0 1-3-0 1-4-0 1W
Titans 1 4 0 0.200 73 141 -68 0-2-0 1-2-0 0-2-0 0-3-0 1-4-0 1W
Jets 0 5 0 0.000 112 157 -45 0-3-0 0-2-0 0-2-0 0-3-0 0-5-0 5L