Butler vs DePaul Prediction, Picks & Odds | 07 Mar 2026

College Basketball Betting Preview: Butler vs DePaul

The Butler Bulldogs battle the DePaul Blue Demons, with tip-off scheduled for 12:00 on Saturday, March 7.

Our betting prediction is that there will be home-court advantage when DePaul play Butler. You can currently get -147 about this happening which look like attractive odds.

Butler Bulldogs were beaten 76-59 in their previous game, being turned over at home to Creighton Bluejays.

DePaul Blue Demons lost their last game, being beaten at home to Villanova Wildcats 76-57.

Head-to-Head Statistics

The last head-to-head saw Butler claim a 87-80 win over DePaul. Butler have a 100% win record when it comes to the previous 10 H2H meetings.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
DePaul	16-14	2121	2082	39	12-7	4-7	1L
Butler	15-15	2378	2319	59	13-7	2-8	2L

View Full Standings

Butler vs DePaul Prediction & Picks

The Butler vs DePaul betting tips feature sharp analysis across major markets, including a key match prediction, correct score guidance and a ready-made bet builder.

Game Prediction

We’re keeping our pick simple and backing DePaul to claim a victory. The home team should be able to win this college matchup and you can get them at a tempting -147.

The college hoops handicappers at Sportsgambler.com regularly track injury updates and pair that with current form. We also tap into a deep stats database to highlight the key numbers that help shape our basketball picks.

Key Butler vs DePaul stats:

• DePaul have won 13 of their last 20 games at home.
• DePaul have won 6 of their last 10 games at home.
• Butler have lost 8 of their last 10 games.
• Butler have lost 4 of their last 5 games on the road.
• Butler have lost their last 2 games.

DePaul Moneyline Probability

The top sportsbooks make it a 59.5% chance that our pick is settled as a winner. Based on our in-depth research, we calculate the actual probability to be 65-70%. The bet can be recommended for this precise reason.

Those looking for a bigger price about a victory for DePaul can check out the Match Result & Total lines. You can combine this moneyline pick with an Under / Over points prediction for more juice.

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Our Game Prediction

DePaul Moneyline @ -147 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Mar 6, 17:02). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Butler 73 - 76 DePaul

Don’t pass up the opportunity to have a speculative wager on the Blue Demons to achieve a 76-73 victory. We don’t think that there will be too much between the teams.

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Butler vs DePaul Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

DePaul are -156 favorites and that means a 61% chance of winning this college game according to the Moneyline betting odds with the sportsbooks. At +130, Butler are regarded as having a lower probability of winning.

The spread is calculated to be 3.5, while total points comes in at 141.5. A bet on the Totals allows fans to use the latest basketball data to good effect. There’s an opportunity to bet Over 141.5 at -115.

The good news is that you’ll find a strong selection of game lines and team props for most college contests. The best basketball betting sites provide a wide range of pre-game and in-game wagering options.

Moneyline

Butler

+130

DePaul

-156

Point Spread

Butler +3.5

-112

DePaul -3.5

-108

Total Points

Under 141.5

-105

Over 141.5

-115

If you have a view on Rebounds, Steals, Blocks, Assists or Points, then the player props could be an option. It’s a fantastic way of betting on a player to perform well and the gambling sites provide lots of choice.

There are some exciting college basketball micro betting lines that are created and they are available in-game. Among them are Next Field Goal, where you select if the shot will be a two or three-pointer. The long-ball option pays better, and in today’s game, you can never discount the three-pointer.

Latest regular season and playoff games stats.

Butler Stats

DePaul Stats

Moneyline

• 2 wins and 8 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 home games

Point Spread

• +2.5 Betting Line: Have covered the spread in 2 of the last 10 games
• +2.5 Betting Line on the Road: Have covered the spread in 3 of the last 10 games on the road

Point Spread

• -2.5 Betting Line: Have covered the spread in 2 of the last 10 games
• -2.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games

Total Points

• Game Totals: An average of 150.80 pts in the previous 10 games
• Game Totals on the Road: An average of 160.00 pts in the previous 10 games on the road
• Over 142.5: Covered in 6 of the previous 10 games
• Over 142.5 on the Road: Covered in 8 of the previous 10 games on the road
• Team Totals: Have scored an average of 70.70 pts and allowed 80.10 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 76.00 pts and allowed 84.00 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 134.80 pts in the previous 10 games
• Game Totals at Home: An average of 135.70 pts in the previous 10 home games
• Over 142.5: Covered in 3 of the previous 10 games
• Over 142.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 65.50 pts and allowed 69.30 pts in the last 10 games
• Team Totals at Home: Have scored an average of 68.80 pts and allowed 66.90 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big East	Overall	PF	PA	N. Pts	Home	Away	Strk
UConn	27-3	2361	1955	406	16-2	11-1	3W
St. John's	24-6	2466	2122	344	15-3	9-3	2W
Villanova	23-7	2314	2109	205	14-3	9-4	1W
Seton Hall	20-10	2116	1945	171	12-4	8-6	1W
DePaul	16-14	2121	2082	39	12-7	4-7	1L
Butler	15-15	2378	2319	59	13-7	2-8	2L
Creighton	15-16	2343	2329	14	11-6	4-10	1W
Providence	14-16	2573	2526	47	10-7	4-9	1L
Xavier	14-16	2351	2390	-39	13-7	1-9	1L
Georgetown	13-17	2231	2213	18	9-8	4-9	7L
Marquette	11-19	2250	2274	-24	9-8	2-11	1W

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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