Canisius vs Duquesne Prediction, Picks & Odds | 22 Dec 2025

College Basketball Betting Preview: Canisius vs Duquesne

The Canisius Golden Griffins square off against the Duquesne Dukes, with tip-off scheduled for 19:00 on Monday, December 22.

We’re predicting that Duquesne will be superior to Canisius and that’s why we’re backing them on the spread at -20.5. Take the -110 that the big favorites are able to cover this line.

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Canisius Golden Griffins were beaten in their previous game and this was on the road. Rhode Island Rams claimed a 62-45 win.

Duquesne Dukes were beaten last game and this was on the road. Nevada Wolf Pack claimed a 78-75 win.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Duquesne	6-5	920	884	36	6-2	0-3	2L
Canisius	5-7	722	810	-88	4-1	1-6	1L

View Full Standings

Canisius vs Duquesne Prediction & Picks

This expert Canisius vs Duquesne betting breakdown features our match prediction, a correct score pick and a carefully constructed bet builder to guide your wagers.

Game Prediction

There’s a case for taking the -110 that Duquesne can overcome the -20.5 in this college showdown. They should be capable of a sizeable win and that means we’re backing the favorites against the spread.

We track all injuries that could impact each team before making our basketball picks. The form guide and latest stats also help the Sportsgambler.com team crunch the numbers ahead of the college hoops action.

Key Canisius vs Duquesne stats:

• The +20.5 line hasn’t been covered by Canisius in 4 of their last 10 games on the road.

Duquesne -20.5 Probability

The best betting sites suggest there’s a 52.4% chance of our pick delivering a return. However, we think that the probability is close to 60% taking all factors into consideration. This is why we can recommend this college basketball bet.

If you want to land bigger odds, you might be interested to know that you can move the betting line. There’s extra juice depending on how risky you want your wager to be.

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Our Game Prediction

Duquesne -20.5 @ -110 Bet Now

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Correct Score Prediction

Canisius 63 - 87 Duquesne

Correct score betting might be tough to predict but there’s a massive potential return if you get it right. We’ll try Duquesne to achieve a 87-63 win at huge odds.

Canisius vs Duquesne Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

At betting odds of -10000 with the sportsbooks, Duquesne are regarded as 99% likely to win this college game. For those wanting to back Canisius, you will find +1800 about the underdogs.

There is a spread of 20.5 and total points has a line of 142.5. There are many ways to bet on basketball including the Totals. There’s an opportunity to bet Over 142.5 at -114.

If you’re planning to place a bet on a college hoops matchup, visit the top basketball betting sites and check out the many available game lines and team props. Find the lines which are the most attractive.

Moneyline

Canisius

+1800

Duquesne

-10000

Point Spread

Canisius +20.5

-112

Duquesne -20.5

-110

Total Points

Under 142.5

-112

Over 142.5

-114

We’re fond of player props as an alternative to betting on the game result. The gambling sites will have Points, Assists, Three-Pointers, Rebounds and Steals among the choices and you can take a particular view.

Instead of focusing on the overall outcome, some bettors prefer to look at the college basketball micro betting lines. As the name suggests, it means placing short-term in-game wagers and this might include Next Field Goal, with the options being for a two-pointer or a three-pointer.

Latest regular season and playoff games stats.

Canisius Stats

Duquesne Stats

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +20.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +20.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• -20.5 Betting Line: Have covered the spread in 1 of the last 10 games
• -20.5 Betting Line at Home: Have covered the spread in 1 of the last 10 home games

Total Points

• Game Totals: An average of 126.90 pts in the previous 10 games
• Game Totals on the Road: An average of 135.10 pts in the previous 10 games on the road
• Over 142.5: Covered in 2 of the previous 10 games
• Over 142.5 on the Road: Covered in 3 of the previous 10 games on the road
• Team Totals: Have scored an average of 59.00 pts and allowed 67.90 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 59.70 pts and allowed 75.40 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 165.80 pts in the previous 10 games
• Game Totals at Home: An average of 162.30 pts in the previous 10 home games
• Over 142.5: Covered in the previous 10 games
• Over 142.5 at Home: Covered in 9 of the previous 10 home games
• Team Totals: Have scored an average of 83.70 pts and allowed 82.10 pts in the last 10 games
• Team Totals at Home: Have scored an average of 85.10 pts and allowed 77.20 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic 10	Overall	PF	PA	N. Pts	Home	Away	Strk
Saint Louis	11-1	1114	833	281	10-1	1-0	5W
George Mason	11-1	960	793	167	9-0	2-1	2W
St. Bonaventure	11-2	1019	906	113	8-0	3-2	1W
Richmond	10-2	1006	840	166	8-0	2-2	1W
Davidson	8-3	827	739	88	6-3	2-0	1L
Dayton	9-4	1035	914	121	8-2	1-2	1L
Fordham	8-4	916	750	166	7-2	1-2	2W
VCU	8-4	1026	860	166	7-2	1-2	2W
George Washington	8-4	1042	907	135	6-2	2-2	2L
Rhode Island	8-4	892	798	94	5-2	3-2	1W
Saint Joseph's	6-4	756	723	33	6-0	0-4	1W
Duquesne	6-5	920	884	36	6-2	0-3	2L
Loyola Chicago	4-9	902	998	-96	3-6	1-3	1W
La Salle	3-9	793	866	-73	3-3	0-6	6L

Metro Atlantic Athletic	Overall	PF	PA	N. Pts	Home	Away	Strk
Siena	9-3	844	758	86	4-1	5-2	1L
Marist	8-3	810	695	115	6-1	2-2	1W
Quinnipiac	9-4	1024	955	69	5-1	4-3	1L
Iona	9-4	1046	1020	26	4-2	5-2	1W
Fairfield	7-5	891	900	-9	4-1	3-4	2W
Merrimack	6-7	842	936	-94	3-1	3-6	1L
Saint Peter's	4-5	611	648	-37	4-1	0-4	1L
Sacred Heart	5-7	939	937	2	3-1	2-6	1W
Canisius	5-7	722	810	-88	4-1	1-6	1L
Manhattan	5-8	1016	1084	-68	4-2	1-6	1W
Mount St. Mary's	4-9	891	988	-97	2-2	2-7	1W
Niagara	3-9	753	900	-147	2-1	1-8	1W
Rider	1-9	586	736	-150	1-2	0-7	7L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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