Canisius vs Duquesne Prediction, Picks & Odds | 22 Dec 2025

College Basketball Betting Preview: Canisius vs Duquesne

The Canisius Golden Griffins square off against the Duquesne Dukes, with tip-off scheduled for 19:00 on Monday, December 22.

We’re predicting that Duquesne will be superior to Canisius and that’s why we’re backing them on the spread at -20.5. Take the -110 that the big favorites are able to cover this line.

Canisius Golden Griffins were beaten in their previous game and this was on the road. Rhode Island Rams claimed a 62-45 win.

Duquesne Dukes were beaten last game and this was on the road. Nevada Wolf Pack claimed a 78-75 win.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Duquesne	18-15	2584	2481	103	13-7	5-8	1L
Canisius	10-21	1951	2184	-233	7-8	3-13	1L

View Full Standings

Canisius vs Duquesne Prediction & Picks

This expert Canisius vs Duquesne betting breakdown features our match prediction, a correct score pick and a carefully constructed bet builder to guide your wagers.

Game Prediction

There’s a case for taking the -110 that Duquesne can overcome the -20.5 in this college showdown. They should be capable of a sizeable win and that means we’re backing the favorites against the spread.

We track all injuries that could impact each team before making our basketball picks. The form guide and latest stats also help the Sportsgambler.com team crunch the numbers ahead of the college hoops action.

Key Canisius vs Duquesne stats:

• The +20.5 line hasn’t been covered by Canisius in 4 of their last 10 games on the road.

Duquesne -20.5 Probability

The best betting sites suggest there’s a 52.4% chance of our pick delivering a return. However, we think that the probability is close to 60% taking all factors into consideration. This is why we can recommend this college basketball bet.

If you want to land bigger odds, you might be interested to know that you can move the betting line. There’s extra juice depending on how risky you want your wager to be.

Before placing your bets, explore the latest betting offers. Our comprehensive guide features a wide range of welcome bonuses to choose from.

Our Game Prediction

Duquesne -20.5 @ -110 Bet Now

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Correct Score Prediction

Canisius 63 - 87 Duquesne

Correct score betting might be tough to predict but there’s a massive potential return if you get it right. We’ll try Duquesne to achieve a 87-63 win at huge odds.

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Canisius vs Duquesne Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

At betting odds of -5000 with the sportsbooks, Duquesne are regarded as 98% likely to win this college game. For those wanting to back Canisius, you will find +1500 about the underdogs.

There is a spread of 18.5 and total points has a line of 142.5. There are many ways to bet on basketball including the Totals. There’s an opportunity to bet Over 142.5 at -108.

If you’re planning to place a bet on a college hoops matchup, visit the top basketball betting sites and check out the many available game lines and team props. Find the lines which are the most attractive.

Moneyline

Canisius

+1500

Duquesne

-5000

Point Spread

Canisius +18.5

-104

Duquesne -18.5

-118

Total Points

Under 142.5

-112

Over 142.5

-108

We’re fond of player props as an alternative to betting on the game result. The gambling sites will have Points, Assists, Three-Pointers, Rebounds and Steals among the choices and you can take a particular view.

Instead of focusing on the overall outcome, some bettors prefer to look at the college basketball micro betting lines. As the name suggests, it means placing short-term in-game wagers and this might include Next Field Goal, with the options being for a two-pointer or a three-pointer.

Latest regular season and playoff games stats.

Canisius Stats

Duquesne Stats

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +20.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +20.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• -20.5 Betting Line: Have covered the spread in 1 of the last 10 games
• -20.5 Betting Line at Home: Have covered the spread in 1 of the last 10 home games

Total Points

• Game Totals: An average of 126.90 pts in the previous 10 games
• Game Totals on the Road: An average of 135.10 pts in the previous 10 games on the road
• Over 142.5: Covered in 2 of the previous 10 games
• Over 142.5 on the Road: Covered in 3 of the previous 10 games on the road
• Team Totals: Have scored an average of 59.00 pts and allowed 67.90 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 59.70 pts and allowed 75.40 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 165.80 pts in the previous 10 games
• Game Totals at Home: An average of 162.30 pts in the previous 10 home games
• Over 142.5: Covered in the previous 10 games
• Over 142.5 at Home: Covered in 9 of the previous 10 home games
• Team Totals: Have scored an average of 83.70 pts and allowed 82.10 pts in the last 10 games
• Team Totals at Home: Have scored an average of 85.10 pts and allowed 77.20 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic 10	Overall	PF	PA	N. Pts	Home	Away	Strk
Saint Louis	28-5	2879	2294	585	21-2	7-3	1L
VCU	27-7	2773	2430	343	19-3	8-4	6W
George Mason	23-9	2347	2160	187	17-3	6-6	1L
Dayton	23-11	2528	2376	152	16-4	7-7	1L
Saint Joseph's	22-11	2419	2306	113	16-3	6-8	1L
Davidson	20-13	2367	2225	142	12-8	8-5	1L
Duquesne	18-15	2584	2481	103	13-7	5-8	1L
George Washington	18-15	2708	2433	275	13-5	5-10	1L
Fordham	17-15	2235	2095	140	12-8	5-7	1L
Rhode Island	16-16	2236	2182	54	10-7	6-9	2L
St. Bonaventure	17-17	2596	2532	64	10-7	7-10	1L
Richmond	15-17	2455	2366	89	11-8	4-9	4L
La Salle	9-23	2148	2370	-222	7-9	2-14	2L
Loyola Chicago	9-24	2204	2500	-296	6-12	3-12	1L

Metro Atlantic Athletic	Overall	PF	PA	N. Pts	Home	Away	Strk
Merrimack	23-11	2330	2260	70	13-2	10-9	1L
Siena	23-11	2398	2233	165	11-4	12-7	4W
Fairfield	21-13	2528	2432	96	13-4	8-9	1L
Marist	19-12	2160	1979	181	11-4	8-8	1L
Quinnipiac	19-13	2411	2303	108	10-6	9-7	1L
Saint Peter's	17-12	2054	1984	70	13-2	4-10	1L
Iona	18-14	2363	2340	23	11-5	7-9	1L
Mount St. Mary's	15-17	2178	2244	-66	8-5	7-12	1L
Sacred Heart	14-19	2482	2528	-46	8-5	6-14	1L
Manhattan	12-20	2369	2526	-157	8-7	4-13	4L
Canisius	10-21	1951	2184	-233	7-8	3-13	1L
Niagara	8-22	1916	2137	-221	6-7	2-15	1L
Rider	4-25	1840	2204	-364	4-9	0-16	2L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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