Clemson vs Notre Dame Prediction, Picks & Odds | 10 Jan 2026

College Basketball Betting Preview: Clemson vs Notre Dame

The Clemson Tigers go up against the Notre Dame Fighting Irish, with tip-off scheduled for 18:00 on Saturday, January 10.

We’re expecting Over 133.5 points to be scored by Clemson and Notre Dame combined. There’s a juicy -110 for our prediction and we’re anticipating that the scoreboard will tick over.

Clemson Tigers won their previous game, beating SMU Mustangs at home. It was a 74-70 win.

Notre Dame Fighting Irish were defeated in their last game. On the road, they suffered a 72-71 reverse against California Golden Bears.

Head-to-Head Statistics

It was a 83-68 win for Clemson when they last played Notre Dame. The H2H over the past 8 games have seen four wins for both teams.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Clemson	24-10	2521	2269	252	16-3	8-7	1L
Notre Dame	13-18	2308	2335	-27	11-7	2-11	2L

View Full Standings

Clemson vs Notre Dame Prediction & Picks

We cover the key Clemson vs Notre Dame betting angles, showcasing our expert match prediction, correct score selection and a bet builder tailored for the best value.

Game Prediction

The teams are capable of exceeding the set points total line which leads us to predict Over 133.5 as a great pick at -110 for this college matchup.

We only make our basketball picks after confirming the latest college hoops team news. Studying recent form and digging into the most relevant stats also helps us build a complete picture.

Key Clemson vs Notre Dame stats:

• The 133.5 line has been covered in 7 of the last 10 Clemson games on the road.
• The 133.5 line has been covered in 12 of the last 20 Clemson games.
• The 133.5 line has been covered in the last 2 Clemson games.
• The 133.5 line has been covered in the last 4 Notre Dame games at home.
• The 133.5 line has been covered in 8 of the last 10 Notre Dame games at home.
• The 133.5 line has been covered in 16 of the last 20 Notre Dame games at home.

Over 133.5 Probability

The top sportsbooks make it a 52.4% chance that our pick is settled as a winner. In our opinion, there’s actually a probability of success closer to 60%. This college basketball wager can therefore be backed with confidence.

There’s a chance to secure larger odds when you wager on the Totals. The leading sportsbooks allow you to move the line for an Over pick until you’re happy with the potential return.

Don’t miss out on extra value. Our comprehensive guide features a wide range of free bets and sign-up bonuses for new bettors.

Our Game Prediction

Over 133.5 Points @ -110 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Jan 10, 16:56). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Clemson 69 - 70 Notre Dame

We’re expecting a close contest so it might be worth going for the Irish to win by a 70-69 scoreline. You can get a massive price and we should hopefully get a run for our money.

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Clemson vs Notre Dame Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Sportsbooks’ favorites Clemson are regarded as likeliest victors for this college game and the -161 about them triumphing means a 62% chance based on their current Moneyline betting odds. Notre Dame are regarded as a long shot to win and you can currently back them at +134.

The spread currently stands at 2.5 and the total points line is 133.5. There is no denying the popularity of betting on the Totals. There’s an opportunity to bet Over 133.5 at -110.

Consider every angle when placing your college basketball bets. The top betting apps offer a nice selection of team props and game lines and it’s all about finding a wager which matches your prediction of the contest.

Moneyline

Clemson

-161

Notre Dame

+134

Point Spread

Clemson -2.5

-118

Notre Dame +2.5

-104

Total Points

Under 133.5

-110

Over 133.5

-110

Prop betting is very popular, with bettors looking to wager on player props such as Points, Assists, Rebounds, Steals and Three-Pointers. It’s a great way of betting on individual player performance and the gambling sites will provide lots of options.

An increasing number of bettors are now enjoying micro betting on college basketball and it’s something which is available on an in-game basis. Wait for the action to start and then wager on something specific to happen.

Latest regular season and playoff games stats.

Clemson Stats

Notre Dame Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• -2.5 Betting Line: Have covered the spread in 8 of the last 10 games
• -2.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• +2.5 Betting Line: Have covered the spread in 7 of the last 10 games
• +2.5 Betting Line at Home: Have covered the spread in 9 of the last 10 home games

Total Points

• Game Totals: An average of 144.90 pts in the previous 10 games
• Game Totals on the Road: An average of 148.80 pts in the previous 10 games on the road
• Over 133.5: Covered in 5 of the previous 10 games
• Over 133.5 on the Road: Covered in 7 of the previous 10 games on the road
• Team Totals: Have scored an average of 75.40 pts and allowed 69.50 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 75.70 pts and allowed 73.10 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 136.00 pts in the previous 10 games
• Game Totals at Home: An average of 144.20 pts in the previous 10 home games
• Over 133.5: Covered in 6 of the previous 10 games
• Over 133.5 at Home: Covered in 8 of the previous 10 home games
• Team Totals: Have scored an average of 69.70 pts and allowed 66.30 pts in the last 10 games
• Team Totals at Home: Have scored an average of 78.50 pts and allowed 65.70 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	32-2	2798	2147	651	21-0	11-2	11W
Virginia	29-5	2742	2326	416	19-1	10-4	1L
Miami	25-8	2704	2349	355	16-4	9-4	1L
North Carolina	24-8	2553	2282	271	19-1	5-7	2L
Clemson	24-10	2521	2269	252	16-3	8-7	1L
Louisville	23-10	2797	2382	415	16-2	7-8	1L
California	21-11	2492	2344	148	17-4	4-7	2L
Stanford	20-12	2431	2326	105	12-7	8-5	1L
NC State	20-13	2762	2525	237	13-7	7-6	1L
SMU	20-13	2779	2561	218	17-3	3-10	1L
Virginia Tech	19-13	2521	2396	125	15-4	4-9	2L
Florida State	18-15	2652	2572	80	12-8	6-7	1L
Wake Forest	17-16	2602	2543	59	12-6	5-10	1L
Syracuse	15-17	2400	2376	24	12-6	3-11	6L
Notre Dame	13-18	2308	2335	-27	11-7	2-11	2L
Pittsburgh	13-20	2327	2370	-43	8-10	5-10	1L
Boston College	11-20	2090	2191	-101	10-10	1-10	1W
Georgia Tech	11-20	2287	2400	-113	10-10	1-10	12L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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