Clemson vs Syracuse Prediction, Picks & Odds | 31 Dec 2025

College Basketball Betting Preview: Clemson vs Syracuse

The Clemson Tigers go up against the Syracuse Orange, with tip-off scheduled for 14:00 on Wednesday, December 31.

We think a wager on the totals provides value after finding that the line is set at a generous 141.5 points. Expect Clemson and Syracuse to surpass this number at -110.

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Clemson Tigers previous game saw them claim a 68-65 home win over Cincinnati Bearcats.

Syracuse Orange won their last game which was at home. It was a 77-48 triumph against Stonehill Skyhawks.

Head-to-Head Statistics

Clemson beat Syracuse when the teams last met. It was a 86-72 scoreline. Clemson have racked up four straight wins over Syracuse. On the head-to-head front, they have won 7 of the past 10.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Clemson	10-3	1036	856	180	9-0	1-3	3W
Syracuse	9-4	970	843	127	8-1	1-3	3W

View Full Standings

Clemson vs Syracuse Prediction & Picks

Get the edge with our Clemson vs Syracuse betting tips: our expert match prediction, most likely correct score outcome and a bet builder tailored for value.

Game Prediction

The Overs is sticking out like a sore thumb considering the line for this college contest is set at 141.5. We’re expecting a bigger total and -110 is available.

Our expert basketball picks always start with checking the latest team news and understanding how it might impact the matchup. From there, we dive into the most valuable college hoops stats to uncover the insights that matter most.

Key Clemson vs Syracuse stats:

• The 141.5 line has been covered in 4 of the last 5 Clemson games on the road.
• The 141.5 line has been covered in 6 of the last 10 Clemson games on the road.
• The 141.5 line has been covered in the last 5 games between these teams.

Over 141.5 Probability

The best sportsbooks are estimating that there is a 52.4% chance of this pick winning. However, our cappers have this figure closer to 60% based on their in-depth research. It's therefore regarded as a value wager.

Want more juice from your Over bet on the Totals? Bigger odds can be found if you move the line and go for a riskier wager. You can choose from a range of options.

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Our Game Prediction

Over 141.5 Points @ -110 Bet Now

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Correct Score Prediction

Clemson 72 - 73 Syracuse

A close game could be on the cards. We’ll bet on Syracuse to secure a 73-72 win at huge odds and this correct score selection should hopefully be a fun one.

Clemson vs Syracuse Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

If you want to bet on Syracuse, then Moneyline odds of +106 are on offer, although Clemson are a -128 chance. This means the leading sportsbooks give the visiting team a 56% chance of success.

The spread is calculated to be 1.5, while total points comes in at 141.5. A Total bet is always available and can often provide value selections. There’s an opportunity to bet Over 141.5 at -110.

The top basketball sportsbooks offer a huge selection of game lines and team props when it comes to most college games. Make sure you look through all the available options before deciding which bet to place.

Moneyline

Clemson

-128

Syracuse

+106

Point Spread

Clemson -1.5

-110

Syracuse +1.5

-110

Total Points

Under 141.5

-110

Over 141.5

-110

Prop bets don’t involve betting on a team to win and instead might look at a player’s individual performance. For example, the number of Points they might score or the number of Assists they might have.

There are some exciting college basketball micro betting lines that are created and they are available in-game. Among them are Next Field Goal, where you select if the shot will be a two or three-pointer. The long-ball option pays better, and in today’s game, you can never discount the three-pointer.

Latest regular season and playoff games stats.

Clemson Stats

Syracuse Stats

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• -1.5 Betting Line: Have covered the spread in 7 of the last 10 games
• -1.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• +1.5 Betting Line: Have covered the spread in 7 of the last 10 games
• +1.5 Betting Line at Home: Have covered the spread in the last 10 home games

Total Points

• Game Totals: An average of 147.10 pts in the previous 10 games
• Game Totals on the Road: An average of 146.60 pts in the previous 10 games on the road
• Over 141.5: Covered in 5 of the previous 10 games
• Over 141.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 76.80 pts and allowed 70.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 76.00 pts and allowed 70.60 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 142.50 pts in the previous 10 games
• Game Totals at Home: An average of 139.50 pts in the previous 10 home games
• Over 141.5: Covered in 4 of the previous 10 games
• Over 141.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 72.20 pts and allowed 70.30 pts in the last 10 games
• Team Totals at Home: Have scored an average of 77.60 pts and allowed 61.90 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
North Carolina	12-1	1058	826	232	10-0	2-1	6W
California	12-1	1080	867	213	12-0	0-1	9W
Duke	11-1	1046	751	295	8-0	3-1	1L
Virginia	11-1	1046	798	248	9-0	2-1	6W
Miami	11-2	1163	880	283	9-1	2-1	6W
SMU	11-2	1184	994	190	10-0	1-2	2W
Virginia Tech	11-2	1080	944	136	9-0	2-2	5W
Stanford	11-2	1064	940	124	7-2	4-0	4W
Louisville	10-2	1099	818	281	8-0	2-2	1W
Clemson	10-3	1036	856	180	9-0	1-3	3W
NC State	9-4	1148	938	210	8-2	1-2	2W
Syracuse	9-4	970	843	127	8-1	1-3	3W
Wake Forest	9-4	1091	966	125	7-2	2-2	1L
Notre Dame	9-4	997	889	108	8-1	1-3	1L
Georgia Tech	9-4	995	914	81	9-2	0-2	4W
Florida State	7-6	1105	1018	87	7-3	0-3	2W
Pittsburgh	7-6	962	881	81	6-3	1-3	2W
Boston College	7-6	918	867	51	6-5	1-1	2W

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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