Clemson vs Syracuse Prediction, Picks & Odds | 31 Dec 2025

College Basketball Betting Preview: Clemson vs Syracuse

The Clemson Tigers go up against the Syracuse Orange, with tip-off scheduled for 14:00 on Wednesday, December 31.

We think a wager on the totals provides value after finding that the line is set at a generous 141.5 points. Expect Clemson and Syracuse to surpass this number at -110.

Clemson Tigers previous game saw them claim a 68-65 home win over Cincinnati Bearcats.

Syracuse Orange won their last game which was at home. It was a 77-48 triumph against Stonehill Skyhawks.

Head-to-Head Statistics

Clemson beat Syracuse when the teams last met. It was a 86-72 scoreline. Clemson have racked up four straight wins over Syracuse. On the head-to-head front, they have won 7 of the past 10.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Clemson	24-10	2521	2269	252	16-3	8-7	1L
Syracuse	15-17	2400	2376	24	12-6	3-11	6L

View Full Standings

Clemson vs Syracuse Prediction & Picks

Get the edge with our Clemson vs Syracuse betting tips: our expert match prediction, most likely correct score outcome and a bet builder tailored for value.

Game Prediction

The Overs is sticking out like a sore thumb considering the line for this college contest is set at 141.5. We’re expecting a bigger total and -110 is available.

Our expert basketball picks always start with checking the latest team news and understanding how it might impact the matchup. From there, we dive into the most valuable college hoops stats to uncover the insights that matter most.

Key Clemson vs Syracuse stats:

• The 141.5 line has been covered in 4 of the last 5 Clemson games on the road.
• The 141.5 line has been covered in 6 of the last 10 Clemson games on the road.
• The 141.5 line has been covered in the last 5 games between these teams.

Over 141.5 Probability

The best sportsbooks are estimating that there is a 52.4% chance of this pick winning. However, our cappers have this figure closer to 60% based on their in-depth research. It's therefore regarded as a value wager.

Want more juice from your Over bet on the Totals? Bigger odds can be found if you move the line and go for a riskier wager. You can choose from a range of options.

Don’t place a bet without checking our comprehensive guide to today’s best free bets and welcome bonuses.

Our Game Prediction

Over 141.5 Points @ -110 Bet Now

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Correct Score Prediction

Clemson 72 - 73 Syracuse

A close game could be on the cards. We’ll bet on Syracuse to secure a 73-72 win at huge odds and this correct score selection should hopefully be a fun one.

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Clemson vs Syracuse Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

If you want to bet on Syracuse, then Moneyline odds of -114 are on offer, although Clemson are a -105 chance. This means the leading sportsbooks give the visiting team a 51% chance of success.

The spread is calculated to be 1.5, while total points comes in at 141.5. A Total bet is always available and can often provide value selections. There’s an opportunity to bet Over 141.5 at -115.

The top basketball sportsbooks offer a huge selection of game lines and team props when it comes to most college games. Make sure you look through all the available options before deciding which bet to place.

Moneyline

Clemson

-105

Syracuse

-114

Point Spread

Clemson +1.5

-120

Syracuse -1.5

-102

Total Points

Under 141.5

-105

Over 141.5

-115

Prop bets don’t involve betting on a team to win and instead might look at a player’s individual performance. For example, the number of Points they might score or the number of Assists they might have.

There are some exciting college basketball micro betting lines that are created and they are available in-game. Among them are Next Field Goal, where you select if the shot will be a two or three-pointer. The long-ball option pays better, and in today’s game, you can never discount the three-pointer.

Latest regular season and playoff games stats.

Clemson Stats

Syracuse Stats

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• -1.5 Betting Line: Have covered the spread in 7 of the last 10 games
• -1.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• +1.5 Betting Line: Have covered the spread in 7 of the last 10 games
• +1.5 Betting Line at Home: Have covered the spread in the last 10 home games

Total Points

• Game Totals: An average of 147.10 pts in the previous 10 games
• Game Totals on the Road: An average of 146.60 pts in the previous 10 games on the road
• Over 141.5: Covered in 5 of the previous 10 games
• Over 141.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 76.80 pts and allowed 70.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 76.00 pts and allowed 70.60 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 142.50 pts in the previous 10 games
• Game Totals at Home: An average of 139.50 pts in the previous 10 home games
• Over 141.5: Covered in 4 of the previous 10 games
• Over 141.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 72.20 pts and allowed 70.30 pts in the last 10 games
• Team Totals at Home: Have scored an average of 77.60 pts and allowed 61.90 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	32-2	2798	2147	651	21-0	11-2	11W
Virginia	29-5	2742	2326	416	19-1	10-4	1L
Miami	25-8	2704	2349	355	16-4	9-4	1L
North Carolina	24-8	2553	2282	271	19-1	5-7	2L
Clemson	24-10	2521	2269	252	16-3	8-7	1L
Louisville	23-10	2797	2382	415	16-2	7-8	1L
California	21-11	2492	2344	148	17-4	4-7	2L
Stanford	20-12	2431	2326	105	12-7	8-5	1L
NC State	20-13	2762	2525	237	13-7	7-6	1L
SMU	20-13	2779	2561	218	17-3	3-10	1L
Virginia Tech	19-13	2521	2396	125	15-4	4-9	2L
Florida State	18-15	2652	2572	80	12-8	6-7	1L
Wake Forest	17-16	2602	2543	59	12-6	5-10	1L
Syracuse	15-17	2400	2376	24	12-6	3-11	6L
Notre Dame	13-18	2308	2335	-27	11-7	2-11	2L
Pittsburgh	13-20	2327	2370	-43	8-10	5-10	1L
Boston College	11-20	2090	2191	-101	10-10	1-10	1W
Georgia Tech	11-20	2287	2400	-113	10-10	1-10	12L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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