Creighton vs Xavier Prediction, Picks & Odds | 17 Dec 2025

College Basketball Betting Preview: Creighton vs Xavier

The Creighton Bluejays square off against the Xavier Musketeers, with tip-off scheduled for 18:30 on Wednesday, December 17.

We expect Xavier to cover the -2.5 line on the spread. This is a really good number and that’s why we’re playing the favorites at -114 to overcome Creighton.

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Creighton Bluejays lost their previous game, being beaten at home to Kansas State Wildcats 83-76.

Xavier Musketeers won their last game which was at home. It was a 75-57 triumph against Missouri State Bears.

Head-to-Head Statistics

The last head-to-head saw Xavier claim a 83-61 win over Creighton. Xavier have triumphed in six of the previous 10 clashes between these teams.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Xavier	8-3	862	786	76	8-2	0-1	5W
Creighton	5-5	746	726	20	5-1	0-4	2L

View Full Standings

Creighton vs Xavier Prediction & Picks

Our Creighton vs Xavier tips include the main match prediction, a correct score forecast and bet builder picks. Each section below offers expert insight into the key betting angles.

Game Prediction

It’s awesome to see Xavier given a -2.5 line on the spread at odds of -114 as we’re expecting a bigger margin of victory in this college contest.

Tracking injury updates is a big part of our college hoops analysis and team news plays a major role in shaping our basketball picks. We combine this with recent form and the most important stats to get a complete picture.

Key Creighton vs Xavier stats:

• The -2.5 line has been covered by Xavier in 5 consecutive games.
• The -2.5 line has been covered by Xavier in 8 of their last 10 games at home.
• The -2.5 line has been covered by Xavier in 16 of their last 20 games at home.
• The +2.5 line hasn’t been covered by Creighton in 5 consecutive games on the road.
• The +2.5 line hasn’t been covered by Creighton in 8 of their last 10 games on the road.
• The +2.5 line hasn’t been covered by Creighton in 12 of their last 20 games on the road.
• The -2.5 line has been covered by Xavier in 6 of their last 10 games against Creighton.

Xavier -2.5 Probability

The best sportsbooks are estimating that there is a 53.2% chance of this pick winning. Based on our in-depth research, we calculate the actual probability to be closer to 60%. It's therefore regarded as a value wager.

If you want to pimp the odds about Xavier covering the line, you might consider going down the Bet Builder route and combine this prediction with other selections.

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Our Game Prediction

Xavier -2.5 @ -114 Bet Now

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Correct Score Prediction

Creighton 68 - 75 Xavier

There’s the chance to land huge betting odds when it comes to Xavier winning on the correct score lines. We’ll try a 75-68 victory in their favor and this should be in the right ball park.

Creighton vs Xavier Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

For this college game, the sportsbooks’ Moneyline betting odds mean Xavier are -164 favorites to win and that means a 62% chance of landing a victory. At +136, Creighton are regarded as having a lower probability of winning.

The current spread is 2.5 and total points is 150.5. There are many ways to bet on basketball including the Totals. There’s the chance to back Under 150.5 at -110.

Whether you’re betting pre-game or in-game, the top basketball sportsbooks serve up a wide range of team props and game lines to choose from. The options are nearly endless, and it’s great to have so much variety.

Moneyline

Creighton

+136

Xavier

-164

Point Spread

Creighton +2.5

-106

Xavier -2.5

-114

Total Points

Under 150.5

-110

Over 150.5

-110

We’re fond of player props as an alternative to betting on the game result. The gambling sites will have Points, Assists, Three-Pointers, Rebounds and Steals among the choices and you can take a particular view.

It’s good to consider all wagering options when it comes to college basketball and micro betting can be an exciting way to get involved in the action. When everything goes in-game, consider whether the next shot will be a Two or a Three-pointer.

Latest regular season and playoff games stats.

Creighton Stats

Xavier Stats

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 home games

Point Spread

• +2.5 Betting Line: Have covered the spread in 5 of the last 10 games
• +2.5 Betting Line on the Road: Have covered the spread in 2 of the last 10 games on the road

Point Spread

• -2.5 Betting Line: Have covered the spread in 7 of the last 10 games
• -2.5 Betting Line at Home: Have covered the spread in 8 of the last 10 home games

Total Points

• Game Totals: An average of 147.20 pts in the previous 10 games
• Game Totals on the Road: An average of 146.70 pts in the previous 10 games on the road
• Over 150.5: Covered in 5 of the previous 10 games
• Over 150.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 74.60 pts and allowed 72.60 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 68.50 pts and allowed 78.20 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 152.00 pts in the previous 10 games
• Game Totals at Home: An average of 150.50 pts in the previous 10 home games
• Over 150.5: Covered in 6 of the previous 10 games
• Over 150.5 at Home: Covered in 6 of the previous 10 home games
• Team Totals: Have scored an average of 79.60 pts and allowed 72.40 pts in the last 10 games
• Team Totals at Home: Have scored an average of 80.00 pts and allowed 70.50 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big East	Overall	PF	PA	N. Pts	Home	Away	Strk
UConn	11-1	948	740	208	8-1	3-0	7W
Seton Hall	10-1	842	678	164	7-0	3-1	4W
Villanova	8-2	804	681	123	7-0	1-2	1W
Butler	8-3	961	839	122	8-1	0-2	1L
Xavier	8-3	862	786	76	8-2	0-1	5W
St. John's	7-3	879	723	156	6-2	1-1	3W
Georgetown	7-3	782	741	41	6-1	1-2	1W
DePaul	8-4	917	825	92	7-3	1-1	1L
Providence	7-5	1100	1016	84	6-1	1-4	1L
Creighton	5-5	746	726	20	5-1	0-4	2L
Marquette	5-6	868	843	25	5-3	0-3	2L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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