Mercyhurst vs Syracuse Prediction, Picks & Odds | 17 Dec 2025

College Basketball Betting Preview: Mercyhurst vs Syracuse

The Mercyhurst Lakers battle the Syracuse Orange, with tip-off scheduled for 19:00 on Wednesday, December 17.

There’s everything to like about the -21.5 line that Syracuse have to cover against Mercyhurst. Take the -102 and feel confident that the favorites get the job done.

Mercyhurst Lakers lost on the road in their previous game. Davidson Wildcats won 80-47.

Syracuse Orange were defeated last time out. They were beaten at home to Hofstra Pride by a 70-69 scoreline.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Mercyhurst	17-17	2357	2291	66	12-3	5-14	1L
Syracuse	15-17	2400	2376	24	12-6	3-11	6L

View Full Standings

Mercyhurst vs Syracuse Prediction & Picks

Prepare for Mercyhurst vs Syracuse with our expert betting guide featuring a trusted match prediction, a correct score recommendation and a well-crafted bet builder.

Game Prediction

Syracuse should enjoy a substantial win in this college showdown and that’s why we’re taking the -21.5 about them on the spread. We expect our pick to cover the line at -102.

Sportsgambler.com brings strong college hoops expertise, built on knowing the team news as soon as it’s confirmed. Recent form plays a big part in our basketball picks and we always back it up with the most relevant stats.

Key Mercyhurst vs Syracuse stats:

• The +21.5 line hasn’t been covered by Mercyhurst in 2 of their last 5 games.

Syracuse -21.5 Probability

The best betting sites make it a 50.5% chance that our pick will deliver a return. However, our cappers think that the probability sits between 55-60% taking all factors into consideration. It is therefore regarded as a value bet.

A Bet Builder provides you with the chance to combine Syracuse against the spread with other picks. For every additional selection, the odds are boosted.

Check our complete list of betting promo codes, free bet deals and the latest welcome bonuses before wagering.

Our Game Prediction

Syracuse -21.5 @ -102 Bet Now

BetMGM Promo Up To $1500 in Bonus Bets Get Bonus T&C apply. Gamble responsibly 18+

Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Dec 16, 23:56). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Mercyhurst 52 - 77 Syracuse

Should you wish to go for a speculative bet, try Syracuse to win 77-52 on the correct score lines. This should be a fun wager which could potentially yield a huge return.

T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Mercyhurst vs Syracuse Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Mercyhurst are such big underdogs for this college game that some sportsbooks aren’t even offering the Moneyline. However, the spread is an attractive option for bettors as it presents a more level playing field.

There is a spread of 24.5 and total points has a line of 130.5. A bet on the Totals allows fans to use the latest basketball data to good effect. There’s the chance to back Under 130.5 at -105.

Consider every angle when placing your college basketball bets. The top betting apps offer a nice selection of team props and game lines and it’s all about finding a wager which matches your prediction of the contest.

Moneyline

Mercyhurst

-

Syracuse

-

Point Spread

Mercyhurst +24.5

-105

Syracuse -24.5

-115

Total Points

Under 130.5

-105

Over 130.5

-115

If you’re looking for an alternative to the main game lines, check out the player props instead. It’s great to wager on Total Points, Three-Pointers, Assists, Steals, Blocks and Rebounds as potential options.

It’s good to consider all wagering options when it comes to college basketball and micro betting can be an exciting way to get involved in the action. When everything goes in-game, consider whether the next shot will be a Two or a Three-pointer.

Latest regular season and playoff games stats.

Mercyhurst Stats

Syracuse Stats

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 1 win and 9 defeats in the last 10 games on the road

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 home games

Point Spread

• +21.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +21.5 Betting Line on the Road: Have covered the spread in 7 of the last 10 games on the road

Point Spread

• -21.5 Betting Line: Have covered the spread in 3 of the last 10 games
• -21.5 Betting Line at Home: Have covered the spread in 2 of the last 10 home games

Total Points

• Game Totals: An average of 133.70 pts in the previous 10 games
• Game Totals on the Road: An average of 132.30 pts in the previous 10 games on the road
• Over 135.5: Covered in 5 of the previous 10 games
• Over 135.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 67.40 pts and allowed 66.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 59.80 pts and allowed 72.50 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 137.60 pts in the previous 10 games
• Game Totals at Home: An average of 144.30 pts in the previous 10 home games
• Over 135.5: Covered in 4 of the previous 10 games
• Over 135.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 72.60 pts and allowed 65.00 pts in the last 10 games
• Team Totals at Home: Have scored an average of 78.30 pts and allowed 66.00 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	32-2	2798	2147	651	21-0	11-2	11W
Virginia	29-5	2742	2326	416	19-1	10-4	1L
Miami	25-8	2704	2349	355	16-4	9-4	1L
North Carolina	24-8	2553	2282	271	19-1	5-7	2L
Clemson	24-10	2521	2269	252	16-3	8-7	1L
Louisville	23-10	2797	2382	415	16-2	7-8	1L
California	21-11	2492	2344	148	17-4	4-7	2L
Stanford	20-12	2431	2326	105	12-7	8-5	1L
NC State	20-13	2762	2525	237	13-7	7-6	1L
SMU	20-13	2779	2561	218	17-3	3-10	1L
Virginia Tech	19-13	2521	2396	125	15-4	4-9	2L
Florida State	18-15	2652	2572	80	12-8	6-7	1L
Wake Forest	17-16	2602	2543	59	12-6	5-10	1L
Syracuse	15-17	2400	2376	24	12-6	3-11	6L
Notre Dame	13-18	2308	2335	-27	11-7	2-11	2L
Pittsburgh	13-20	2327	2370	-43	8-10	5-10	1L
Boston College	11-20	2090	2191	-101	10-10	1-10	1W
Georgia Tech	11-20	2287	2400	-113	10-10	1-10	12L

Northeast	Overall	PF	PA	N. Pts	Home	Away	Strk
LIU	24-10	2519	2418	101	14-1	10-9	5W
Central Conn. St.	18-12	2215	2127	88	10-4	8-8	1L
Mercyhurst	17-17	2357	2291	66	12-3	5-14	1L
Le Moyne	15-17	2336	2341	-5	10-4	5-13	2L
New Haven	14-17	2013	2055	-42	9-6	5-11	1W
Wagner	13-17	2118	2186	-68	7-5	6-12	1L
Stonehill	12-21	2191	2263	-72	8-6	4-15	1L
Fairleigh Dickinson	11-21	2150	2245	-95	8-6	3-15	4L
St. Francis (PA)	7-24	2216	2510	-294	5-9	2-15	2L
Chicago State	7-25	2105	2434	-329	5-6	2-19	3L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

Top Basketball Pages