DePaul vs Villanova Prediction, Picks & Odds | 31 Dec 2025

College Basketball Betting Preview: DePaul vs Villanova

The DePaul Blue Demons battle the Villanova Wildcats, with tip-off scheduled for 18:00 on Wednesday, December 31.

The total line of 136.5 points looks pretty low and we can take advantage by backing the Overs at -110. We can see DePaul and Villanova combining to go bigger.

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DePaul Blue Demons lost when they last took to the court. They were turned over 72-54 at home to UConn Huskies.

Villanova Wildcats triumphed in their last game. It was on the road where Seton Hall Pirates were beaten 64-56.

Head-to-Head Statistics

The scoreline was 59-49 in favor of Villanova when they last played DePaul. Villanova have six straight victories against DePaul. They have won 9 of the 10 previous head-to-head matchups.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Villanova	10-2	944	803	141	8-0	2-2	3W
DePaul	8-5	971	897	74	7-4	1-1	2L

View Full Standings

DePaul vs Villanova Prediction & Picks

Discover our expert DePaul vs Villanova betting tips, featuring a match prediction, correct score suggestion and bet builder advice. Scroll down for full analysis.

Game Prediction

We’ll take a chance on a total bet after finding that the line is set at a generous 136.5 points. Expect this number to be surpassed at -110 for this college matchup.

Our expert basketball picks always start with checking the latest team news and understanding how it might impact the matchup. From there, we dive into the most valuable college hoops stats to uncover the insights that matter most.

Key DePaul vs Villanova stats:

• The 136.5 line has been covered in 4 of the last 5 DePaul games on the road.
• The 136.5 line has been covered in 15 of the last 19 DePaul games on the road.
• The 136.5 line has been covered in 9 of the last 10 Villanova games at home.
• The 136.5 line has been covered in 4 of the last 5 Villanova games.
• The 136.5 line has been covered in the last 3 Villanova games at home.

Over 136.5 Probability

The top sportsbooks make it a 52.4% chance that our pick is settled as a winner. After careful examination, our cappers calculate this probability to be closer to 60%. That means we’re regarding it as a value bet.

There are ways to get bigger odds by betting Over on the Totals. Bettors often look to move the line so they can land a more profitable return if the selection wins.

Before your next wager, read our guide featuring today’s top betting offers, free bet deals, and sign-up bonuses.

Our Game Prediction

Over 136.5 Points @ -110 Bet Now

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Correct Score Prediction

DePaul 62 - 79 Villanova

There’s the chance to land huge betting odds when it comes to Villanova winning on the correct score lines. We’ll try a 79-62 victory in their favor and this should be in the right ball park.

DePaul vs Villanova Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Villanova are massive -1250 favorites. They are regarded as 93% likely to win this college game judging by the sportsbooks’ latest Moneyline odds. The market suggests that DePaul are least likely to win at +740.

The spread is 13.5 and the total points line is currently 137.5. The advantage of the Totals is that you only have to choose from one of two options. There’s an opportunity to bet Over 137.5 at -110.

College hoops fans are spoilt for choice thanks to the wide range of team props and game lines which are available for every contest on the coupon. Head to the top basketball sportsbooks and find the best value picks.

Moneyline

DePaul

+740

Villanova

-1250

Point Spread

DePaul +13.5

-110

Villanova -13.5

-110

Total Points

Under 137.5

-110

Over 137.5

-110

You shouldn’t overlook the player props when it comes to betting on individual games. Many gambling sites will give you the chance to get with or bet against a specific player when it comes to number of Points, Assists, Steals and Blocks.

It’s good to consider all wagering options when it comes to college basketball and micro betting can be an exciting way to get involved in the action. When everything goes in-game, consider whether the next shot will be a Two or a Three-pointer.

Latest regular season and playoff games stats.

DePaul Stats

Villanova Stats

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 games on the road

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• +13.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +13.5 Betting Line on the Road: Have covered the spread in 8 of the last 10 games on the road

Point Spread

• -13.5 Betting Line: Have covered the spread in 6 of the last 10 games
• -13.5 Betting Line at Home: Have covered the spread in 7 of the last 10 home games

Total Points

• Game Totals: An average of 145.90 pts in the previous 10 games
• Game Totals on the Road: An average of 142.10 pts in the previous 10 games on the road
• Over 136.5: Covered in 7 of the previous 10 games
• Over 136.5 on the Road: Covered in 7 of the previous 10 games on the road
• Team Totals: Have scored an average of 75.40 pts and allowed 70.50 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 67.20 pts and allowed 74.90 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 144.20 pts in the previous 10 games
• Game Totals at Home: An average of 156.60 pts in the previous 10 home games
• Over 136.5: Covered in 7 of the previous 10 games
• Over 136.5 at Home: Covered in 9 of the previous 10 home games
• Team Totals: Have scored an average of 78.40 pts and allowed 65.80 pts in the last 10 games
• Team Totals at Home: Have scored an average of 86.60 pts and allowed 70.00 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big East	Overall	PF	PA	N. Pts	Home	Away	Strk
UConn	12-1	1020	794	226	8-1	4-0	8W
Seton Hall	12-2	1049	882	167	7-1	5-1	1W
Villanova	10-2	944	803	141	8-0	2-2	3W
Butler	10-4	1208	1038	170	10-1	0-3	1L
Georgetown	9-4	1034	957	77	7-2	2-2	1W
Xavier	9-4	999	961	38	8-3	1-1	1W
St. John's	8-4	1030	860	170	7-2	1-2	1W
Creighton	9-5	1109	1000	109	8-1	1-4	4W
DePaul	8-5	971	897	74	7-4	1-1	2L
Providence	7-6	1167	1088	79	6-2	1-4	2L
Marquette	5-9	1073	1084	-11	5-5	0-4	5L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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