Howard vs Duke Prediction, Picks & Odds | 23 Nov 2025

College Basketball Betting Preview: Howard vs Duke

The Howard Bison square off against the Duke Blue Devils, with tip-off scheduled for 16:00 on Sunday, November 23.

We have decided to go for Duke against the spread in order to get the best value. They should be able to cover an appealing -39.5 line at -118 when they take on Howard.

Howard Bison claimed a victory in their previous game. A 80-70 home win occurred against Niagara Purple Eagles.

Duke Blue Devils won their last game which was at home. It was a 100-42 triumph against Niagara Purple Eagles.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	32-2	2798	2147	651	21-0	11-2	11W
Howard	23-10	2556	2236	320	16-4	7-6	8W

View Full Standings

Howard vs Duke Prediction & Picks

Take on Howard vs Duke with our in-depth betting analysis, featuring an expert match prediction, scoreline advice and a value-driven bet builder. Scroll down for the full breakdown.

Game Prediction

Duke can enjoy a huge victory in this college matchup and a wager on the spread could be the best way forward. Back the big favorites off -39.5 to cover the line at -118.

Knowing which players are injured gives us a valuable edge when making basketball predictions. After reviewing the form guide, we turn to the latest stats to shape our college hoops picks.

Key Howard vs Duke stats:

• The -39.5 line has been covered by Duke in 3 of their last 5 games.

Duke -39.5 Probability

If you go by the top sportsbooks, our pick has a 54.1% chance of winning. Our experts think there’s a stronger chance of success and calculate the probability to be closer to 60%. The bet can be recommended for this precise reason.

If you’re in pursuit of bigger odds, then a Bet Builder could be the way forward. Take Duke to cover the line with additional selections until you’re satisfied with the price.

Before you back your picks, see how far a bonus can take you — our guide highlights the top betting offers live now.

Our Game Prediction

Duke -39.5 @ -118 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Nov 22, 21:55). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Howard 50 - 93 Duke

For those wanting a big return from a small stake, consider the correct score lines. For example, Duke can be backed to win 93-50 at huge betting odds.

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Howard vs Duke Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The Spread offers a better alternative to the Moneyline considering Duke are huge favorites for this college game. Consider whether to side with them to cover the line or alternatively wager on the underdogs to outperform their odds.

The current spread is 42.5 and the total points line is 153.5. There are many ways to bet on basketball including the Totals. If you fancy Under 153.5, then the odds are -105.

Consider every angle when placing your college hoops bets. The top basketball betting sites offer a huge selection of game lines and team props, and it’s all about finding a wager that fits your prediction of the game.

Moneyline

Howard

-

Duke

-

Point Spread

Howard +42.5

-110

Duke -42.5

-110

Total Points

Under 153.5

-105

Over 153.5

-115

If you’re looking for an alternative to the main game lines, check out the player props instead. It’s great to wager on Total Points, Three-Pointers, Assists, Steals, Blocks and Rebounds as potential options.

You don’t have to wait for the final outcome when it comes to college basketball micro betting. Instead, there’s the opportunity to wager on live lines which tend to be settled in a shorter space of time and the in-game odds are always changing.

Latest regular season and playoff games stats.

Howard Stats

Duke Stats

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• +39.5 Betting Line: Have covered the spread in the last 10 games
• +39.5 Betting Line on the Road: Have covered the spread in the last 10 games on the road

Point Spread

• -39.5 Betting Line: Have covered the spread in 3 of the last 10 games
• -39.5 Betting Line at Home: Have covered the spread in 3 of the last 10 home games

Total Points

• Game Totals: An average of 150.10 pts in the previous 10 games
• Game Totals on the Road: An average of 148.10 pts in the previous 10 games on the road
• Over 150.5: Covered in 3 of the previous 10 games
• Over 150.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 74.80 pts and allowed 75.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 69.80 pts and allowed 78.30 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 154.00 pts in the previous 10 games
• Game Totals at Home: An average of 150.90 pts in the previous 10 home games
• Over 150.5: Covered in 4 of the previous 10 games
• Over 150.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 90.30 pts and allowed 63.70 pts in the last 10 games
• Team Totals at Home: Have scored an average of 88.20 pts and allowed 62.70 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	32-2	2798	2147	651	21-0	11-2	11W
Virginia	29-5	2742	2326	416	19-1	10-4	1L
Miami	25-8	2704	2349	355	16-4	9-4	1L
North Carolina	24-8	2553	2282	271	19-1	5-7	2L
Clemson	24-10	2521	2269	252	16-3	8-7	1L
Louisville	23-10	2797	2382	415	16-2	7-8	1L
California	21-11	2492	2344	148	17-4	4-7	2L
Stanford	20-12	2431	2326	105	12-7	8-5	1L
NC State	20-13	2762	2525	237	13-7	7-6	1L
SMU	20-13	2779	2561	218	17-3	3-10	1L
Virginia Tech	19-13	2521	2396	125	15-4	4-9	2L
Florida State	18-15	2652	2572	80	12-8	6-7	1L
Wake Forest	17-16	2602	2543	59	12-6	5-10	1L
Syracuse	15-17	2400	2376	24	12-6	3-11	6L
Notre Dame	13-18	2308	2335	-27	11-7	2-11	2L
Pittsburgh	13-20	2327	2370	-43	8-10	5-10	1L
Boston College	11-20	2090	2191	-101	10-10	1-10	1W
Georgia Tech	11-20	2287	2400	-113	10-10	1-10	12L

Mid-Eastern Athletic	Overall	PF	PA	N. Pts	Home	Away	Strk
Howard	23-10	2556	2236	320	16-4	7-6	8W
Norfolk State	15-17	2445	2362	83	9-6	6-11	3L
Morgan State	14-16	2258	2347	-89	9-7	5-9	1L
NC Central	14-18	2299	2415	-116	10-5	4-13	1L
South Carolina St.	10-22	2147	2522	-375	6-5	4-17	1L
UMES	9-23	2060	2265	-205	6-4	3-19	3L
Delaware State	8-23	1896	2185	-289	5-8	3-15	1L
Coppin State	7-24	2032	2493	-461	3-8	4-16	3L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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