Illinois State vs Southern Illinois Prediction, Picks & Odds | 18 Dec 2025

College Basketball Betting Preview: Illinois State vs Southern Illinois

The Illinois State Redbirds square off against the Southern Illinois Salukis, with tip-off scheduled for 21:00 on Thursday, December 18.

If you are looking for a value pick, then -141 that Southern Illinois beat Illinois State certainly stands out. We’re expecting the home team to win on the Moneyline and there are generous odds available.

Illinois State Redbirds lost their previous game, being beaten at home to Utah State Aggies 83-78.

Southern Illinois Salukis lost on the road in their last game. Richmond Spiders won 93-84 (OT).

Head-to-Head Statistics

Southern Illinois won the last matchup between the pair. Enjoying a 88-79 triumph when facing Illinois State. We’ve seen seven Southern Illinois wins in the past 10 meetings between the teams.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Illinois State	20-12	2404	2190	214	15-4	5-8	1L
Southern Illinois	16-16	2336	2226	110	8-8	8-8	1L

View Full Standings

Illinois State vs Southern Illinois Prediction & Picks

This expert Illinois State vs Southern Illinois betting breakdown features our match prediction, a correct score pick and a carefully constructed bet builder to guide your wagers.

Game Prediction

Southern Illinois should prove too strong for their opponents and our pick is to side with them on the Moneyline. There is a generous -141 for the home team to win this college contest.

We put solid research behind every basketball pick, starting with recent form and a clear read on injuries. From there, key college hoops stats and advanced metrics help complete the picture and support smarter betting decisions.

Key Illinois State vs Southern Illinois stats:

• Southern Illinois have won 4 of their last 5 games at home.
• Southern Illinois have won 7 of their last 10 games at home.
• Southern Illinois have won 2 consecutive games at home.
• Illinois State have lost 12 of their last 20 games on the road.
• Southern Illinois have won 7 of their last 10 games against Illinois State.

Southern Illinois Moneyline Probability

If you go by the best sportsbooks, our pick has a 58.5% chance of landing a return. After careful examination, our analysts calculate this probability to be somewhere between 65-70%. It is the reason why we are recommending this college basketball wager.

Southern Illinois can be backed in different ways and you might find the odds more attractive when you check out the Point Spread or the Result & Both Teams to Score lines.

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Our Game Prediction

Southern Illinois Moneyline @ -141 Bet Now

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Correct Score Prediction

Illinois State 75 - 79 Southern Illinois

There might not be too much between these teams, with our correct score pick being a 79-75 win for Southern Illinois. There are huge odds available when it comes to this selection.

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Illinois State vs Southern Illinois Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Southern Illinois are -125 to win against Illinois State who are priced at betting odds of +104. From a percentage point-of-view, the leading sportsbooks give the visiting team a 49% chance of success.

1.5 is the spread and 154.5 is the total points line. Basketball bettors love the chance to get an alternative angle by going for a Total wager. If you want to back Over 154.5, it’s -115.

You can find a nice selection of game lines and team props for most college basketball matchups, with the top betting apps creating many different options. Check out the pre-game and in-game selections before placing your bets.

Moneyline

ISU

+104

Southern Illinois

-125

Point Spread

ISU +1.5

-110

Southern Illinois -1.5

-110

Total Points

Under 154.5

-105

Over 154.5

-115

There is regularly betting value to be found from wagering on the player props with the best online gambling sites. You can find lots of ways to back for or against a specific player lining up for one of the two teams.

There are always opportunities to enjoy college basketball micro betting. It’s generally the case that you will find player and team props in-game and bettors can use their insight to wager on outcomes such as if the next shot will be a Two or Three-Pointer.

Latest regular season and playoff games stats.

Illinois State Stats

Southern Illinois Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +1.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +1.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• -1.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -1.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 149.50 pts in the previous 10 games
• Game Totals on the Road: An average of 150.70 pts in the previous 10 games on the road
• Over 150.5: Covered in 4 of the previous 10 games
• Over 150.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 82.50 pts and allowed 67.00 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 74.00 pts and allowed 76.70 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 157.00 pts in the previous 10 games
• Game Totals at Home: An average of 152.10 pts in the previous 10 home games
• Over 150.5: Covered in 6 of the previous 10 games
• Over 150.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 80.40 pts and allowed 76.60 pts in the last 10 games
• Team Totals at Home: Have scored an average of 81.40 pts and allowed 70.70 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Missouri Valley	Overall	PF	PA	N. Pts	Home	Away	Strk
Belmont	26-6	2684	2347	337	15-3	11-3	2L
Northern Iowa	23-12	2447	2144	303	13-5	10-7	5W
Bradley	21-12	2560	2422	138	17-4	4-8	1L
Illinois State	20-12	2404	2190	214	15-4	5-8	1L
Murray State	20-12	2667	2558	109	14-4	6-8	2L
UIC	19-15	2567	2379	188	11-7	8-8	1L
Valparaiso	17-15	2278	2300	-22	13-4	4-11	1L
Southern Illinois	16-16	2336	2226	110	8-8	8-8	1L
Drake	14-20	2552	2544	8	7-12	7-8	1L
Indiana State	11-21	2354	2383	-29	8-7	3-14	1L
Evansville	7-25	2143	2447	-304	5-12	2-13	2L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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