Iowa State vs BYU Prediction, Picks & Odds | 21 Feb 2026

College Basketball Betting Preview: Iowa State vs BYU

The Iowa State Cyclones square off against the Brigham Young Cougars, with tip-off scheduled for 22:30 on Saturday, February 21.

It’s time to go for Iowa State against the spread, especially with a -3.5 line at odds of -104. Our betting prediction is that this can be comfortably achieved when they play BYU.

Iowa State Cyclones won their previous game which was at home. It was a 70-67 triumph against Houston Cougars.

Brigham Young Cougars were defeated in their last game. On the road, they suffered a 75-68 reverse against Arizona Wildcats.

Head-to-Head Statistics

BYU have beaten Iowa State in their last two matchups. On the road, they won 88-85 (OT) and followed up with a 96-92 home win. We’ve seen three BYU wins in the past 4 meetings between the teams.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Iowa State	23-3	2175	1680	495	17-0	6-3	2W
BYU	19-7	2230	1938	292	14-3	5-4	1L

View Full Standings

Iowa State vs BYU Prediction & Picks

This Iowa State vs BYU betting breakdown features a main match prediction, a correct score insight and a sharply constructed bet builder to guide your wagers.

Game Prediction

Iowa State should be able to cover the -3.5 line in this college contest. We’re confident of a strong showing and betting the favorites against the spread is the best play at odds of -104.

Tracking injury updates is a big part of our college hoops analysis and team news plays a major role in shaping our basketball picks. We combine this with recent form and the most important stats to get a complete picture.

Key Iowa State vs BYU stats:

• The -3.5 line has been covered by Iowa State in 15 of their last 20 games.
• The +3.5 line hasn’t been covered by BYU in 3 of their last 5 games.

Iowa State -3.5 Probability

When you look at the latest odds, our pick has a 51% chance of landing a return. Our analysts think there’s a stronger chance of success and calculate the probability to be 55-60%. It’s the reason why we are recommending this college basketball bet.

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Our Game Prediction

Iowa State -3.5 @ -104 Bet Now

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Correct Score Prediction

Iowa State 78 - 70 BYU

A 78-70 win for the Cyclones is clearly a risky bet although this could be an exciting correct score option where there’s the chance to enjoy a huge potential return.

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Iowa State vs BYU Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Iowa State are regarded as having a 63% chance of winning this college game according to the latest betting odds. The sportsbooks have priced them up at -169. Brigham Young Cougars are the underdogs at +140 and they’re regarded as least likely to win.

There is a spread of 3.5 and total points has a line of 155.5. The Totals offers basketball fans an alternative way of getting involved. Those that want to back Under 155.5 can find odds of -110 available.

You’ll find a broad selection of team props and game lines for most college contests, with the best basketball betting sites offering plenty of options. Be sure to review both the pre-game and in-game markets before placing your bets.

Moneyline

Iowa State

-169

BYU

+140

Point Spread

Iowa State -3.5

-104

BYU +3.5

-118

Total Points

Under 155.5

-110

Over 155.5

-110

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Latest regular season and playoff games stats.

Iowa State Stats

Brigham Young Cougars Stats

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 home games

Point Spread

• -3.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -3.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• +3.5 Betting Line: Have covered the spread in 5 of the last 10 games
• +3.5 Betting Line at Home: Have covered the spread in 9 of the last 10 home games

Total Points

• Game Totals: An average of 144.00 pts in the previous 10 games
• Game Totals on the Road: An average of 152.20 pts in the previous 10 games on the road
• Over 155.5: Covered in 2 of the previous 10 games
• Over 155.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 76.70 pts and allowed 67.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 78.90 pts and allowed 73.30 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 165.70 pts in the previous 10 games
• Game Totals at Home: An average of 162.80 pts in the previous 10 home games
• Over 155.5: Covered in 6 of the previous 10 games
• Over 155.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 81.80 pts and allowed 83.90 pts in the last 10 games
• Team Totals at Home: Have scored an average of 89.70 pts and allowed 73.10 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big 12	Overall	PF	PA	N. Pts	Home	Away	Strk
Arizona	24-2	2281	1783	498	16-1	8-1	1W
Houston	23-3	2024	1602	422	16-1	7-2	1L
Iowa State	23-3	2175	1680	495	17-0	6-3	2W
Kansas	20-6	2009	1769	240	14-1	6-5	1W
Texas Tech	19-7	2117	1881	236	14-2	5-5	1L
BYU	19-7	2230	1938	292	14-3	5-4	1L
UCF	18-7	2044	1935	109	14-3	4-4	1W
West Virginia	16-10	1809	1655	154	13-5	3-5	1L
TCU	16-10	2043	1884	159	12-5	4-5	1L
Oklahoma State	16-10	2187	2114	73	13-4	3-6	4L
Cincinnati	14-12	1879	1741	138	13-4	1-8	3W
Arizona State	14-12	2040	2046	-6	10-6	4-6	2W
Colorado	14-12	2081	2042	39	13-5	1-7	2L
Baylor	13-13	2158	1993	165	10-7	3-6	4L
Kansas State	11-15	2095	2091	4	10-7	1-8	1W
Utah	10-16	1970	2044	-74	9-6	1-10	1W

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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