Iowa State vs Creighton Prediction, Picks & Odds | 25 Nov 2025

College Basketball Betting Preview: Iowa State vs Creighton

The Iowa State Cyclones square off against the Creighton Bluejays, with tip-off scheduled for 14:00 on Tuesday, November 25.

We’re confident that Creighton can produce a strong performance against Iowa State. Our prediction is that they’ll cover the spread of +8.5 and you can currently get -110.

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Iowa State Cyclones won their previous game 83-82. This was a road victory against St. John's Red Storm.

Creighton Bluejays suffered a defeat in their last game. A 81-74 scoreline occurred on the road against Baylor Bears.

Head-to-Head Statistics

It was a 64-58 win for Iowa State when they last played Creighton.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Iowa State	5-0	465	331	134	3-0	2-0	5W
Creighton	3-2	388	352	36	3-0	0-2	1L

View Full Standings

Iowa State vs Creighton Prediction & Picks

This Iowa State vs Creighton betting breakdown features a main match prediction, a correct score insight and a sharply constructed bet builder to guide your wagers.

Game Prediction

We’re happy to get with Creighton against the spread in this college game. -110 is available that they are able to cover +8.5 and that looks more than reasonable.

The college hoops handicappers at Sportsgambler.com regularly track injury updates and pair that with current form. We also tap into a deep stats database to highlight the key numbers that help shape our basketball picks.

Key Iowa State vs Creighton stats:

• The +8.5 line has been covered by Creighton in 18 consecutive games at home.
• The -8.5 line hasn’t been covered by Iowa State in 12 of their last 19 games on the road.
• The -8.5 line hasn’t been covered by Iowa State in 6 of their last 10 games on the road.

Creighton +8.5 Probability

Based on the odds from the top betting sites, there’s a 52.4% likelihood of our pick delivering a return. However, our cappers have this figure closer to 60% based on their in-depth research. This college basketball wager can therefore be backed with confidence.

If you want to back Creighton without taking them on the spread, there’s the alternative to go for a Winning Margin wager instead. There are lots of different options here.

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Our Game Prediction

Creighton +8.5 @ -110 Bet Now

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Correct Score Prediction

Iowa State 80 - 75 Creighton

There’s the chance to land huge betting odds when it comes to the Cyclones winning on the correct score lines. We’ll try a 80-75 victory in their favor and this should be in the right ball park.

Iowa State vs Creighton Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Iowa State are strong -455 favorites to win this college game according to the Moneyline betting odds. The sportsbooks give them a 82% chance of claiming victory. If you’re looking for an alternative angle, Creighton are trading at +350.

8.5 is where the spread lies, with total points being 152.5 right now. The Totals offers basketball fans an alternative way of getting involved. The Over 152.5 selection is available to back at -110.

The top basketball sportsbooks offer a huge selection of game lines and team props when it comes to most college games. Make sure you look through all the available options before deciding which bet to place.

Moneyline

Iowa State

-455

Creighton

+350

Point Spread

Iowa State -8.5

-110

Creighton +8.5

-110

Total Points

Under 152.5

-110

Over 152.5

-110

The gambling sites will have player props available for each game. Check out the various betting odds and take a view on whether a player’s Total Points, Three-Pointers, Blocks or Steals will hit over or under a certain line.

There are always opportunities to enjoy college basketball micro betting. It’s generally the case that you will find player and team props in-game and bettors can use their insight to wager on outcomes such as if the next shot will be a Two or Three-Pointer.

Latest regular season and playoff games stats.

Iowa State Stats

Creighton Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• -8.5 Betting Line: Have covered the spread in 7 of the last 10 games
• -8.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road

Point Spread

• +8.5 Betting Line: Have covered the spread in 7 of the last 10 games
• +8.5 Betting Line at Home: Have covered the spread in the last 10 home games

Total Points

• Game Totals: An average of 155.20 pts in the previous 10 games
• Game Totals on the Road: An average of 148.90 pts in the previous 10 games on the road
• Over 151.5: Covered in 6 of the previous 10 games
• Over 151.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 86.60 pts and allowed 68.60 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 75.10 pts and allowed 73.80 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 150.30 pts in the previous 10 games
• Game Totals at Home: An average of 146.10 pts in the previous 10 home games
• Over 151.5: Covered in 6 of the previous 10 games
• Over 151.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 76.90 pts and allowed 73.40 pts in the last 10 games
• Team Totals at Home: Have scored an average of 79.20 pts and allowed 66.90 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big East	Overall	PF	PA	N. Pts	Home	Away	Strk
Seton Hall	6-0	450	347	103	5-0	1-0	6W
Georgetown	5-0	411	349	62	4-0	1-0	5W
UConn	5-1	503	368	135	4-1	1-0	1W
Butler	5-1	542	436	106	5-0	0-1	2W
Villanova	4-1	411	337	74	3-0	1-1	4W
DePaul	4-2	484	410	74	4-2	0-0	2W
Providence	4-2	559	495	64	3-0	1-2	2W
St. John's	3-2	476	369	107	3-2	0-0	1L
Creighton	3-2	388	352	36	3-0	0-2	1L
Marquette	4-3	584	521	63	4-2	0-1	1W
Xavier	4-3	524	514	10	4-2	0-1	1W

Big 12	Overall	PF	PA	N. Pts	Home	Away	Strk
Iowa State	5-0	465	331	134	3-0	2-0	5W
Houston	6-0	460	341	119	5-0	1-0	6W
Oklahoma State	6-0	559	446	113	6-0	0-0	6W
Arizona	6-0	513	408	105	4-0	2-0	6W
Colorado	5-0	472	408	64	5-0	0-0	5W
Baylor	4-0	349	305	44	4-0	0-0	4W
Cincinnati	5-1	472	385	87	5-1	0-0	1W
Kansas State	5-1	557	477	80	5-0	0-1	1L
UCF	5-1	522	467	55	4-1	1-0	4W
Utah	5-1	518	481	37	5-1	0-0	1L
BYU	4-1	436	343	93	4-1	0-0	1W
Arizona State	4-1	385	345	40	3-1	1-0	2W
West Virginia	5-2	499	422	77	5-0	0-2	2L
Kansas	4-2	458	380	78	4-0	0-2	1W
Texas Tech	4-2	493	450	43	4-0	0-2	1L
TCU	3-2	400	318	82	3-2	0-0	1W

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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