Iowa State vs Creighton Prediction, Picks & Odds | 25 Nov 2025
College Basketball Betting Preview: Iowa State vs Creighton
The Iowa State Cyclones square off against the Creighton Bluejays, with tip-off scheduled for 14:00 on Tuesday, November 25.
We’re confident that Creighton can produce a strong performance against Iowa State. Our prediction is that they’ll cover the spread of +8.5 and you can currently get -110.
Iowa State Cyclones won their previous game 83-82. This was a road victory against St. John's Red Storm.
Creighton Bluejays suffered a defeat in their last game. A 81-74 scoreline occurred on the road against Baylor Bears.
Head-to-Head Statistics
It was a 64-58 win for Iowa State when they last played Creighton.
| NCAAB | Overall | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|
Iowa State
|
27-7 | 2781 | 2215 | 566 | 19-1 | 8-6 | 1L |
Creighton
|
15-17 | 2404 | 2401 | 3 | 11-6 | 4-11 | 1L |
Iowa State vs Creighton Prediction & Picks
The Iowa State vs Creighton betting tips feature sharp analysis across major markets, including a key match prediction, player prop bets, correct score guidance and a ready-made bet builder.
Game Prediction
We’re happy to get with Creighton against the spread in this college game. -110 is available that they are able to cover +8.5 and that looks more than reasonable.
The college hoops handicappers at Sportsgambler.com regularly track injury updates and pair that with current form. We also tap into a deep stats database to highlight the key numbers that help shape our basketball picks.
Key Iowa State vs Creighton stats:
Creighton +8.5 Probability
Based on the odds from the top betting sites, there’s a 52.4% likelihood of our pick delivering a return. However, our cappers have this figure closer to 60% based on their in-depth research. This college basketball wager can therefore be backed with confidence.
If you want to back Creighton without taking them on the spread, there’s the alternative to go for a Winning Margin wager instead. There are lots of different options here.
Before you bet, make sure to check out the latest offers. Our guide is packed with the best welcome bonuses from leading sportsbooks.
Player Prop Picks
Joshua Jefferson (Iowa State) is available at +120 to have Over 4.5 assists. The total is attractive when it comes to betting on Player Assists and we’re confident of landing a return.
Latest Joshua Jefferson Player Prop Odds
Blake Harper (Creighton) can be wagered to total Over 11.5 points at -135. There’s a fairly strong case that he will be able to cover the line and we’ll wager on his Player Points.
Latest Blake Harper Player Prop Odds
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
Take a same game parlay that incorporates Creighton to cover the +7.5 spread combined with Over 152.5. Add in Joshua Jefferson (Iowa State) to get Over 4.5 assists.
Should you want to back different picks for the same game, then a same game parlay will suit your needs. The betting sites create this personalised basketball wagering tool where you can choose different selections and combine the odds together.
Correct Score Prediction
80
-
75
Creighton
There’s the chance to land huge betting odds when it comes to the Cyclones winning on the correct score lines. We’ll try a 80-75 victory in their favor and this should be in the right ball park.
Iowa State vs Creighton Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
Iowa State are strong -278 favorites to win this college game according to the Moneyline betting odds. The sportsbooks give them a 74% chance of claiming victory. If you’re looking for an alternative angle, Creighton are trading at +220.
6.5 is where the spread lies, with total points being 150.5 right now. The Totals offers basketball fans an alternative way of getting involved. The Over 150.5 selection is available to back at -115.
The top basketball sportsbooks offer a huge selection of game lines and team props when it comes to most college games. Make sure you look through all the available options before deciding which bet to place.
The favorite to hit the most buckets is Milan Momcilovic. Odds of -125 can be found for him scoring Over 16.5 points and there is -105 for him to go Under.
There are always opportunities to enjoy college basketball micro betting. It’s generally the case that you will find player and team props in-game and bettors can use their insight to wager on outcomes such as if the next shot will be a Two or Three-Pointer.
Latest regular season and playoff games stats.
Iowa State Stats
Creighton Stats
- 8 wins and 2 defeats in the last 10 games
- 5 wins and 5 defeats in the last 10 games on the road
- -8.5 Betting Line: Have covered the spread in 7 of the last 10 games
- -8.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road
- +8.5 Betting Line: Have covered the spread in 7 of the last 10 games
- +8.5 Betting Line at Home: Have covered the spread in the last 10 home games
- Game Totals: An average of 155.20 pts in the previous 10 games
- Game Totals on the Road: An average of 148.90 pts in the previous 10 games on the road
- Over 151.5: Covered in 6 of the previous 10 games
- Over 151.5 on the Road: Covered in 4 of the previous 10 games on the road
- Team Totals: Have scored an average of 86.60 pts and allowed 68.60 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 75.10 pts and allowed 73.80 pts in the last 10 games on the road
- Game Totals: An average of 150.30 pts in the previous 10 games
- Game Totals at Home: An average of 146.10 pts in the previous 10 home games
- Over 151.5: Covered in 6 of the previous 10 games
- Over 151.5 at Home: Covered in 3 of the previous 10 home games
- Team Totals: Have scored an average of 76.90 pts and allowed 73.40 pts in the last 10 games
- Team Totals at Home: Have scored an average of 79.20 pts and allowed 66.90 pts in the last 10 home games
NCAAB Table Select Season
| Big East | Overall | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|
UConn
|
29-5 | 2635 | 2214 | 421 | 18-2 | 11-3 | 1L |
St. John's
|
28-6 | 2773 | 2379 | 394 | 18-3 | 10-3 | 6W |
Villanova
|
24-8 | 2469 | 2265 | 204 | 15-4 | 9-4 | 1L |
Seton Hall
|
21-12 | 2321 | 2156 | 165 | 13-5 | 8-7 | 1L |
DePaul
|
16-16 | 2248 | 2226 | 22 | 12-9 | 4-7 | 3L |
Butler
|
16-16 | 2540 | 2481 | 59 | 13-8 | 3-8 | 1L |
Georgetown
|
16-18 | 2503 | 2479 | 24 | 10-8 | 6-10 | 1L |
|
Creighton
|
15-17 | 2404 | 2401 | 3 | 11-6 | 4-11 | 1L |
Providence
|
15-18 | 2815 | 2772 | 43 | 10-7 | 5-11 | 1L |
Xavier
|
15-18 | 2586 | 2661 | -75 | 13-7 | 2-11 | 1L |
Marquette
|
12-20 | 2405 | 2425 | -20 | 10-9 | 2-11 | 1L |
| Big 12 | Overall | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|
Arizona
|
32-2 | 2929 | 2339 | 590 | 21-1 | 11-1 | 9W |
Houston
|
28-6 | 2623 | 2137 | 486 | 20-2 | 8-4 | 1L |
|
Iowa State
|
27-7 | 2781 | 2215 | 566 | 19-1 | 8-6 | 1L |
Kansas
|
23-10 | 2496 | 2290 | 206 | 17-2 | 6-8 | 1L |
Texas Tech
|
22-10 | 2573 | 2324 | 249 | 16-4 | 6-6 | 3L |
BYU
|
23-11 | 2853 | 2561 | 292 | 17-4 | 6-7 | 1L |
TCU
|
22-11 | 2584 | 2378 | 206 | 16-5 | 6-6 | 1L |
UCF
|
21-11 | 2591 | 2511 | 80 | 15-5 | 6-6 | 1L |
Oklahoma State
|
19-14 | 2781 | 2736 | 45 | 14-5 | 5-9 | 1L |
West Virginia
|
18-14 | 2214 | 2072 | 142 | 15-6 | 3-8 | 1L |
Cincinnati
|
18-15 | 2413 | 2230 | 183 | 16-4 | 2-11 | 1L |
Colorado
|
17-15 | 2559 | 2542 | 17 | 15-7 | 2-8 | 2L |
Arizona State
|
17-16 | 2519 | 2585 | -66 | 13-6 | 4-10 | 1L |
Baylor
|
16-16 | 2642 | 2469 | 173 | 12-8 | 4-8 | 1L |
Kansas State
|
12-20 | 2546 | 2619 | -73 | 11-8 | 1-12 | 2L |
Utah
|
10-22 | 2379 | 2531 | -152 | 9-9 | 1-13 | 6L |
- Overall = Overall Wins-Losses
- PF = Total Points For
- PA = Total Points Against
- N. Pts = Point Differential
- Home = Home Record
- Away = Away Record
- Strk = Current Streak
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