Louisville vs North Carolina Prediction, Picks & Odds | 23 Feb 2026

College Basketball Betting Preview: Louisville vs North Carolina

The Louisville Cardinals battle the North Carolina Tar Heels, with tip-off scheduled for 19:00 on Monday, February 23.

We’re not convinced Louisville and North Carolina are cumulatively going to produce enough points in relation to the total line. Therefore, we’re aiming to go Under 162.5 at -105.

Louisville Cardinals won their previous game, beating Georgia Tech Yellow Jackets at home. It was a 87-70 win.

North Carolina Tar Heels won their last game 77-64. This was a road victory against Syracuse Orange.

Head-to-Head Statistics

It was a 83-70 win for Louisville when they last played North Carolina. In the past 10 games between the teams, North Carolina have won seven.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
North Carolina	21-6	2180	1907	273	16-0	5-6	1W
Louisville	20-7	2344	1938	406	14-2	6-5	1W

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Louisville vs North Carolina Prediction & Picks

Our Louisville vs North Carolina tips include the main match prediction, a correct score forecast and bet builder picks. Each section below offers expert insight into the key betting angles.

Game Prediction

We’ve identified a betting angle for this college matchup on the totals. Our pick is Under 162.5 points which can currently be backed at odds of -105.

The college hoops handicappers at Sportsgambler.com start by analyzing recent form and staying on top of injury news before making any basketball picks. From there, we interpret the story the stats are telling to help shape our predictions.

Key Louisville vs North Carolina stats:

• The 162.5 line hasn’t been covered in 15 of the last 20 Louisville games on the road.
• The 162.5 line hasn’t been covered in 7 of the last 10 Louisville games.
• The 162.5 line hasn’t been covered in the last 5 UNC games.
• The 162.5 line hasn’t been covered in 8 of the last 10 UNC games at home.
• The 162.5 line hasn’t been covered in 16 of the last 20 UNC games at home.
• The 162.5 line hasn’t been covered in the last 4 games between these teams.

Under 162.5 Probability

The best betting apps make it a 51.3% chance that our pick is settled as a winner. After careful examination, our cappers calculate this probability to be somewhere between 55-60%. This is why we can recommend this college basketball bet.

The top sportsbooks will allow you to shoot for bigger odds on your Under wager. By moving the line and going for a lower Total, there’s the chance to get more juice.

Before you place your bets, explore our updated guide packed with the latest free bets and betting bonuses.

Our Game Prediction

Under 162.5 Points @ -105 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Feb 22, 23:02). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Louisville 78 - 77 North Carolina

We’ll roll the dice and go for Louisville to register a 78-77 victory. We don’t think that there will be too much between the teams and we’re happy to take the massive odds.

T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Louisville vs North Carolina Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Louisville are -143 favorites and that means a 59% chance of winning this college game according to the Moneyline betting odds with the sportsbooks. For those wanting to oppose the market leader, you can get +118 about North Carolina.

2.5 is where the spread lies, with total points being 162.5 right now. Basketball fans regularly enjoy the opportunity to bet on the Totals. There’s the chance to back Under 162.5 at -105.

If you’re planning to place a bet on a college hoops matchup, visit the top basketball betting sites and check out the many available game lines and team props. Find the lines which are the most attractive.

Moneyline

Louisville

-143

UNC

+118

Point Spread

Louisville -2.5

-102

UNC +2.5

-120

Total Points

Under 162.5

-105

Over 162.5

-115

As an alternative to the game lines and team props, check out the player props that are available. These can be a great alternative if you want to focus on a player’s performance. The best gambling sites will provide lots of options.

An increasing number of bettors are now enjoying micro betting on college basketball and it’s something which is available on an in-game basis. Wait for the action to start and then wager on something specific to happen.

Latest regular season and playoff games stats.

Louisville Stats

North Carolina Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 10 wins and 0 defeats in the last 10 home games

Point Spread

• -3.5 Betting Line: Have covered the spread in 8 of the last 10 games
• -3.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• +3.5 Betting Line: Have covered the spread in 7 of the last 10 games
• +3.5 Betting Line at Home: Have covered the spread in the last 10 home games

Total Points

• Game Totals: An average of 160.60 pts in the previous 10 games
• Game Totals on the Road: An average of 159.00 pts in the previous 10 games on the road
• Over 162.5: Covered in 3 of the previous 10 games
• Over 162.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 86.10 pts and allowed 74.50 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 80.20 pts and allowed 78.80 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 152.20 pts in the previous 10 games
• Game Totals at Home: An average of 149.20 pts in the previous 10 home games
• Over 162.5: Covered in 3 of the previous 10 games
• Over 162.5 at Home: Covered in 2 of the previous 10 home games
• Team Totals: Have scored an average of 78.30 pts and allowed 73.90 pts in the last 10 games
• Team Totals at Home: Have scored an average of 83.10 pts and allowed 66.10 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	25-2	2225	1705	520	16-0	9-2	4W
Virginia	24-3	2215	1836	379	14-1	10-2	8W
Miami	21-6	2239	1904	335	14-3	7-3	1L
North Carolina	21-6	2180	1907	273	16-0	5-6	1W
Louisville	20-7	2344	1938	406	14-2	6-5	1W
Clemson	20-8	2087	1837	250	13-3	7-5	4L
NC State	19-8	2291	1992	299	12-5	7-3	1W
SMU	19-8	2344	2094	250	16-2	3-6	2W
California	19-8	2125	1963	162	16-3	3-5	2W
Virginia Tech	18-10	2206	2073	133	14-3	4-7	1W
Stanford	16-11	2027	1958	69	10-6	6-5	2L
Syracuse	15-13	2117	2054	63	12-5	3-8	2L
Florida State	14-13	2159	2097	62	10-7	4-6	3W
Wake Forest	14-13	2140	2084	56	10-6	4-7	1L
Notre Dame	12-15	2009	1982	27	10-5	2-10	1L
Georgia Tech	11-17	2075	2165	-90	10-8	1-9	9L
Pittsburgh	10-17	1891	1934	-43	8-9	2-8	1W
Boston College	9-18	1828	1907	-79	8-10	1-8	8L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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