Marquette vs DePaul Prediction, Picks & Odds | 16 Jan 2026

College Basketball Betting Preview: Marquette vs DePaul

The Marquette Golden Eagles battle the DePaul Blue Demons, with tip-off scheduled for 20:30 on Friday, January 16.

Don’t miss out on the chance to side with DePaul on the spread at -3.5. On the face of it, this seems a generous line and odds of -105 can be backed against Marquette.

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Marquette Golden Eagles were defeated in their previous game. On the road, they suffered a 92-68 reverse against St. John's Red Storm.

DePaul Blue Demons lost on the road in their last game. UConn Huskies won 72-60.

Head-to-Head Statistics

Marquette had the edge in the most recent matchup between these teams. They recorded a 68-58 win over DePaul. Marquette have six straight victories against DePaul. They have won 8 of the 10 previous head-to-head matchups.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
DePaul	10-7	1239	1167	72	9-4	1-3	1L
Marquette	6-12	1337	1390	-53	6-6	0-6	2L

View Full Standings

Marquette vs DePaul Prediction & Picks

Our Marquette vs DePaul tips include the main match prediction, a correct score forecast and bet builder picks. Each section below offers expert insight into the key betting angles.

Game Prediction

DePaul are available at odds of -105 when it comes to backing them against the spread in this college contest. The appealing -3.5 line could be covered with ease by the favorites and this looks like a value bet.

Incoming team news often impacts the betting lines and odds in significant ways. Our college hoops handicappers factor this in alongside recent form, while key stats are also carefully weighed to strengthen each basketball pick.

Key Marquette vs DePaul stats:

• The -3.5 line has been covered by DePaul in 4 of their last 5 games at home.
• The -3.5 line has been covered by DePaul in 7 of their last 10 games at home.
• The -3.5 line has been covered by DePaul in 2 consecutive games at home.
• The +3.5 line hasn’t been covered by Marquette in 7 consecutive games on the road.
• The +3.5 line hasn’t been covered by Marquette in 8 of their last 10 games on the road.
• The +3.5 line hasn’t been covered by Marquette in 13 of their last 20 games on the road.

DePaul -3.5 Probability

Based on the latest odds from the top sportsbooks, our pick carries a 51.3% chance of winning. Based on our in-depth research, we calculate the actual probability to be 55-60%. The bet can be recommended for this precise reason.

There’s the chance to sell points and that means moving the line until you’re happy with the wager. It means a riskier bet but a bigger return on the odds available.

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Our Game Prediction

DePaul -3.5 @ -105 Bet Now

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Correct Score Prediction

Marquette 71 - 78 DePaul

Should you want a bet that can land a monster return, then look no further than the correct score lines. Back the Blue Demons to win 78-71 and leverage a huge payout if this happens.

Marquette vs DePaul Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

The sportsbooks’ betting odds have DePaul as -185 favorites for this college game, implying that they are 65% likely to win. The market suggests that Marquette are least likely to win at +152.

The spread is calculated to be 3.5, while total points comes in at 142.5. The advantage of the Totals is that you only have to choose from one of two options. If you want to back Over 142.5, it’s -110.

The good news is that you’ll find a strong selection of game lines and team props for most college contests. The best basketball betting sites provide a wide range of pre-game and in-game wagering options.

Moneyline

Marquette

+152

DePaul

-185

Point Spread

Marquette +3.5

-110

DePaul -3.5

-110

Total Points

Under 142.5

-110

Over 142.5

-110

If you’re looking for an alternative to the main game lines, check out the player props instead. It’s great to wager on Total Points, Three-Pointers, Assists, Steals, Blocks and Rebounds as potential options.

It’s good to consider all wagering options when it comes to college basketball and micro betting can be an exciting way to get involved in the action. When everything goes in-game, consider whether the next shot will be a Two or a Three-pointer.

Latest regular season and playoff games stats.

Marquette Stats

DePaul Stats

Moneyline

• 2 wins and 8 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +3.5 Betting Line: Have covered the spread in 3 of the last 10 games
• +3.5 Betting Line on the Road: Have covered the spread in 2 of the last 10 games on the road

Point Spread

• -3.5 Betting Line: Have covered the spread in 4 of the last 10 games
• -3.5 Betting Line at Home: Have covered the spread in 7 of the last 10 home games

Total Points

• Game Totals: An average of 147.30 pts in the previous 10 games
• Game Totals on the Road: An average of 151.70 pts in the previous 10 games on the road
• Over 142.5: Covered in 7 of the previous 10 games
• Over 142.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 67.90 pts and allowed 79.40 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 69.40 pts and allowed 82.30 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 137.60 pts in the previous 10 games
• Game Totals at Home: An average of 146.40 pts in the previous 10 home games
• Over 142.5: Covered in 4 of the previous 10 games
• Over 142.5 at Home: Covered in 6 of the previous 10 home games
• Team Totals: Have scored an average of 68.00 pts and allowed 69.60 pts in the last 10 games
• Team Totals at Home: Have scored an average of 76.90 pts and allowed 69.50 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big East	Overall	PF	PA	N. Pts	Home	Away	Strk
UConn	17-1	1427	1140	287	10-1	7-0	13W
Villanova	14-3	1336	1167	169	9-1	5-2	2W
Seton Hall	14-3	1245	1072	173	8-2	6-1	1L
St. John's	12-5	1462	1231	231	8-3	4-2	3W
Creighton	11-7	1398	1301	97	9-2	2-5	1W
Xavier	11-7	1394	1362	32	10-4	1-3	2W
DePaul	10-7	1239	1167	72	9-4	1-3	1L
Butler	10-7	1420	1296	124	10-3	0-4	4L
Georgetown	9-8	1317	1270	47	7-4	2-4	4L
Providence	8-9	1508	1447	61	6-4	2-5	3L
Marquette	6-12	1337	1390	-53	6-6	0-6	2L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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