Mercyhurst vs Syracuse Prediction, Picks & Odds | 17 Dec 2025

College Basketball Betting Preview: Mercyhurst vs Syracuse

The Mercyhurst Lakers battle the Syracuse Orange, with tip-off scheduled for 19:00 on Wednesday, December 17.

There’s everything to like about the -21.5 line that Syracuse have to cover against Mercyhurst. Take the -102 and feel confident that the favorites get the job done.

Confident in our spread pick? Unlock the best BetMGM promo code and take a moment to read our expert site review before you commit to your play.

Mercyhurst Lakers lost on the road in their previous game. Davidson Wildcats won 80-47.

Syracuse Orange were defeated last time out. They were beaten at home to Hofstra Pride by a 70-69 scoreline.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Syracuse	6-4	726	650	76	5-1	1-3	1L
Mercyhurst	4-7	721	733	-12	3-0	1-7	1L

View Full Standings

Mercyhurst vs Syracuse Prediction & Picks

Prepare for Mercyhurst vs Syracuse with our expert betting guide featuring a trusted match prediction, a correct score recommendation and a well-crafted bet builder.

Game Prediction

Syracuse should enjoy a substantial win in this college showdown and that’s why we’re taking the -21.5 about them on the spread. We expect our pick to cover the line at -102.

Sportsgambler.com brings strong college hoops expertise, built on knowing the team news as soon as it’s confirmed. Recent form plays a big part in our basketball picks and we always back it up with the most relevant stats.

Key Mercyhurst vs Syracuse stats:

• The +21.5 line hasn’t been covered by Mercyhurst in 2 of their last 5 games.

Syracuse -21.5 Probability

The best betting sites make it a 50.5% chance that our pick will deliver a return. However, our cappers think that the probability sits between 55-60% taking all factors into consideration. It is therefore regarded as a value bet.

A Bet Builder provides you with the chance to combine Syracuse against the spread with other picks. For every additional selection, the odds are boosted.

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Our Game Prediction

Syracuse -21.5 @ -102 Bet Now

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Correct Score Prediction

Mercyhurst 52 - 77 Syracuse

Should you wish to go for a speculative bet, try Syracuse to win 77-52 on the correct score lines. This should be a fun wager which could potentially yield a huge return.

Mercyhurst vs Syracuse Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Mercyhurst are such big underdogs for this college game that some sportsbooks aren’t even offering the Moneyline. However, the spread is an attractive option for bettors as it presents a more level playing field.

There is a spread of 20.5 and total points has a line of 134.5. A bet on the Totals allows fans to use the latest basketball data to good effect. There’s the chance to back Under 134.5 at -105.

Consider every angle when placing your college basketball bets. The top betting apps offer a nice selection of team props and game lines and it’s all about finding a wager which matches your prediction of the contest.

Moneyline

Mercyhurst

-

Syracuse

-

Point Spread

Mercyhurst +20.5

-102

Syracuse -20.5

-118

Total Points

Under 134.5

-105

Over 134.5

-115

If you’re looking for an alternative to the main game lines, check out the player props instead. It’s great to wager on Total Points, Three-Pointers, Assists, Steals, Blocks and Rebounds as potential options.

It’s good to consider all wagering options when it comes to college basketball and micro betting can be an exciting way to get involved in the action. When everything goes in-game, consider whether the next shot will be a Two or a Three-pointer.

Latest regular season and playoff games stats.

Mercyhurst Stats

Syracuse Stats

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 1 win and 9 defeats in the last 10 games on the road

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 home games

Point Spread

• +21.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +21.5 Betting Line on the Road: Have covered the spread in 7 of the last 10 games on the road

Point Spread

• -21.5 Betting Line: Have covered the spread in 3 of the last 10 games
• -21.5 Betting Line at Home: Have covered the spread in 2 of the last 10 home games

Total Points

• Game Totals: An average of 133.70 pts in the previous 10 games
• Game Totals on the Road: An average of 132.30 pts in the previous 10 games on the road
• Over 135.5: Covered in 5 of the previous 10 games
• Over 135.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 67.40 pts and allowed 66.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 59.80 pts and allowed 72.50 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 137.60 pts in the previous 10 games
• Game Totals at Home: An average of 144.30 pts in the previous 10 home games
• Over 135.5: Covered in 4 of the previous 10 games
• Over 135.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 72.60 pts and allowed 65.00 pts in the last 10 games
• Team Totals at Home: Have scored an average of 78.30 pts and allowed 66.00 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	11-0	965	669	296	8-0	3-0	11W
North Carolina	10-1	888	705	183	9-0	1-1	4W
California	10-1	909	761	148	10-0	0-1	7W
Virginia	9-1	871	675	196	7-0	2-1	4W
Miami	10-2	1058	813	245	8-1	2-1	5W
Virginia Tech	10-2	998	863	135	8-0	2-2	4W
Louisville	9-2	1005	764	241	7-0	2-2	1L
SMU	9-2	975	849	126	8-0	1-2	1L
Stanford	8-2	823	732	91	5-2	3-0	1W
Clemson	9-3	968	791	177	8-0	1-3	2W
Notre Dame	9-3	928	817	111	8-0	1-3	4W
Wake Forest	8-3	953	800	153	6-1	2-2	2W
NC State	7-4	964	804	160	6-2	1-2	1L
Georgia Tech	7-4	811	768	43	7-2	0-2	2W
Syracuse	6-4	726	650	76	5-1	1-3	1L
Boston College	5-6	774	742	32	4-5	1-1	1L
Florida State	5-6	922	906	16	5-3	0-3	5L
Pittsburgh	5-6	779	772	7	5-3	0-3	3L

Northeast	Overall	PF	PA	N. Pts	Home	Away	Strk
Central Conn. St.	6-4	801	703	98	3-0	3-4	1W
LIU	6-5	843	881	-38	2-1	4-4	1L
Le Moyne	5-6	835	862	-27	3-1	2-5	1L
New Haven	4-6	631	677	-46	3-2	1-4	2L
Mercyhurst	4-7	721	733	-12	3-0	1-7	1L
Stonehill	3-8	778	801	-23	3-1	0-7	1W
Wagner	2-6	602	680	-78	1-0	1-6	1W
Fairleigh Dickinson	2-8	714	783	-69	2-2	0-6	1L
St. Francis (PA)	2-9	760	908	-148	2-2	0-7	2L
Chicago State	2-10	803	1009	-206	1-1	1-9	1L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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