Missouri vs Illinois Prediction, Picks & Odds | 22 Dec 2025

College Basketball Betting Preview: Missouri vs Illinois

The Missouri Tigers go up against the Illinois Fighting Illini, with tip-off scheduled for 20:00 on Monday, December 22.

Missouri should give a good account of themselves against Illinois and the prediction is to bet them on the spread. The +8.5 looks attractive and -105 is available.

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Missouri Tigers previous game saw them claim a 82-60 home win over Bethune-Cookman Wildcats.

Illinois Fighting Illini were defeated last time out. They were beaten at home to Nebraska Cornhuskers by a 83-80 scoreline.

Head-to-Head Statistics

Illini have landed back-to-back victories against Missouri. A home matchup saw them triumph 97-73 and they won 80-77 on the road. The past 7 H2H games have seen Missouri land four wins.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Missouri	10-2	1041	838	203	9-0	1-2	2W
Illinois	8-3	966	787	179	6-3	2-0	1L

View Full Standings

Missouri vs Illinois Prediction & Picks

We cover the key Missouri vs Illinois betting angles, showcasing our expert match prediction, correct score selection and a bet builder tailored for the best value.

Game Prediction

We’re confident of Missouri staying close in this college showdown, with our pick being that they’ll cover the spread. The +8.5 line looks generous at odds of -105.

To deliver the best possible basketball picks, we start by locking in the team news and taking time to review the latest form. There’s also no shortage of data to crunch from the most up-to-date college hoops stats available.

Key Missouri vs Illinois stats:

• The +8.5 line has been covered by Missouri in 9 of their last 10 games.
• The +8.5 line has been covered by Missouri in 16 of their last 20 games.
• The +8.5 line has been covered by Missouri in 2 consecutive games.
• The -8.5 line hasn’t been covered by Illinois in 3 of their last 5 games.
• The -8.5 line hasn’t been covered by Illinois in 11 of their last 20 games at home.
• The -8.5 line hasn’t been covered by Illinois in 2 consecutive games.
• The -8.5 line hasn’t been covered by Illinois in 5 of their last 7 games against Missouri.

Mizzou +8.5 Probability

If you go by the top sportsbooks, our pick has a 51.3% chance of winning. However, we have this number closer to 60% based on our in-depth research. This college basketball bet can therefore be backed with confidence.

A Bet Builder provides you with the opportunity to combine Mizzou on the spread with other picks. For every additional selection, the odds are boosted.

Our user-friendly bonus guide highlights the newest betting offers, free bets, and sign-up deals in one spot.

Our Game Prediction

Missouri +8.5 @ -105 Bet Now

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Correct Score Prediction

Missouri 77 - 83 Illinois

A 83-77 win for the Illini is clearly a risky bet although this could be an exciting correct score option where there’s the chance to enjoy a huge potential return.

Missouri vs Illinois Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

With an estimated 83% chance of winning, the sportsbooks are taking no chances with their -476 betting odds about Illinois triumphing in this college game. The market suggests that Missouri are least likely to win at +360.

The spread currently stands at 8.5 and the total points line is 155.5. There is no denying the popularity of betting on the Totals. There’s an opportunity to bet Over 155.5 at -106.

College hoops fans are spoilt for choice thanks to the wide range of team props and game lines which are available for every contest on the coupon. Head to the top basketball sportsbooks and find the best value picks.

Moneyline

Missouri

+360

Illinois

-476

Point Spread

Missouri +8.5

-105

Illinois -8.5

-115

Total Points

Under 155.5

-114

Over 155.5

-106

If you have a view on Total Points, Three-Pointers, Assists, Double-Doubles or Triple-Doubles, then the player prop betting could be up your street. It’s a great way of wagering on individual performance.

There are some exciting college basketball micro betting lines that are created and they are available in-game. Among them are Next Field Goal, where you select if the shot will be a two or three-pointer. The long-ball option pays better, and in today’s game, you can never discount the three-pointer.

Latest regular season and playoff games stats.

Missouri Stats

Illinois Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +8.5 Betting Line: Have covered the spread in 9 of the last 10 games
• +8.5 Betting Line on the Road: Have covered the spread in 7 of the last 10 games on the road

Point Spread

• -8.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -8.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 155.10 pts in the previous 10 games
• Game Totals on the Road: An average of 164.10 pts in the previous 10 games on the road
• Over 155.5: Covered in 5 of the previous 10 games
• Over 155.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 86.40 pts and allowed 68.70 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 81.80 pts and allowed 82.30 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 158.50 pts in the previous 10 games
• Game Totals at Home: An average of 160.70 pts in the previous 10 home games
• Over 155.5: Covered in 7 of the previous 10 games
• Over 155.5 at Home: Covered in 8 of the previous 10 home games
• Team Totals: Have scored an average of 85.30 pts and allowed 73.20 pts in the last 10 games
• Team Totals at Home: Have scored an average of 88.90 pts and allowed 71.80 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big Ten	Overall	PF	PA	N. Pts	Home	Away	Strk
Michigan	11-0	1049	727	322	8-0	3-0	11W
Nebraska	12-0	1000	806	194	11-0	1-0	12W
USC	12-1	1162	979	183	8-1	4-0	4W
Purdue	11-1	1019	798	221	9-1	2-0	3W
Michigan State	11-1	936	760	176	8-1	3-0	3W
Iowa	10-2	966	719	247	9-0	1-2	2W
UCLA	9-3	965	831	134	8-1	1-2	2W
Indiana	9-3	1020	799	221	9-1	0-2	1W
Ohio State	8-3	946	800	146	6-2	2-1	1L
Illinois	8-3	966	787	179	6-3	2-0	1L
Penn State	8-4	938	899	39	7-3	1-1	3L
Washington	7-4	913	804	109	4-1	3-3	1L
Wisconsin	7-4	917	830	87	6-0	1-4	2L
Northwestern	7-5	967	842	125	6-3	1-2	1L
Minnesota	6-5	807	749	58	6-3	0-2	1W
Oregon	6-6	936	901	35	6-3	0-3	1L
Maryland	6-6	926	966	-40	5-2	1-4	3L
Rutgers	6-6	828	873	-45	6-2	0-4	1W

Southeastern	Overall	PF	PA	N. Pts	Home	Away	Strk
Vanderbilt	12-0	1129	866	263	7-0	5-0	12W
Georgia	10-1	1095	788	307	8-1	2-0	4W
LSU	10-1	963	771	192	7-1	3-0	2W
Missouri	10-2	1041	838	203	9-0	1-2	2W
Texas A&M	9-3	1140	921	219	7-1	2-2	2W
Tennessee	9-3	986	774	212	8-2	1-1	2W
Arkansas	9-3	1074	899	175	8-2	1-1	1L
Alabama	9-3	1127	983	144	7-3	2-0	2W
Oklahoma	8-3	936	818	118	6-0	2-3	2W
Kentucky	8-4	1005	796	209	8-3	0-1	3W
Texas	8-4	1049	856	193	7-2	1-2	1W
Florida	8-4	1012	843	169	8-1	0-3	3W
Auburn	8-4	1011	933	78	7-2	1-2	1L
South Carolina	7-4	862	750	112	7-1	0-3	1L
Ole Miss	7-5	891	821	70	7-1	0-4	1L
Mississippi State	7-5	945	930	15	6-3	1-2	3W

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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